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2'-O-methylation

Index 2'-O-methylation

2'-O-methylation is a common nucleoside modification of RNA, where a methyl group is added to the 2' hydroxyl of the ribose moiety of a nucleoside, producing a methoxy group. [1]

13 relations: Methoxy group, Methyl group, Nucleic acid analogue, Nucleic acid nomenclature, Nucleoside, Ribose, Ribosomal RNA, Ribosome, RMBase (RNA Modification Base), RNA, Small nuclear RNA, Small nucleolar RNA, Spliceosome.

Methoxy group

A methoxy group is the functional group consisting of a methyl group bound to oxygen.

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Methyl group

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.

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Nucleic acid analogue

Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.

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Nucleic acid nomenclature

Molecular biologists use several shorthand terms when referring to nucleic acid molecules, such as DNA and RNA, collectively referred to as nucleic acid nomenclature.

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Nucleoside

Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group.

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Ribose

Ribose is a carbohydrate with the formula C5H10O5; specifically, it is a pentose monosaccharide (simple sugar) with linear form H−(C.

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Ribosomal RNA

Ribosomal ribonucleic acid (rRNA) is the RNA component of the ribosome, and is essential for protein synthesis in all living organisms.

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Ribosome

The ribosome is a complex molecular machine, found within all living cells, that serves as the site of biological protein synthesis (translation).

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RMBase (RNA Modification Base)

is designed for decoding the landscape of RNA modifications identified from high-throughput sequencing data (MeRIP-seq, m6A-seq, miCLIP, m6A-CLIP, Pseudo-seq, Ψ-seq, CeU-seq, Aza-IP, RiboMeth-seq).

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RNA

Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.

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Small nuclear RNA

Small nuclear ribonucleic acid (snRNA), also commonly referred to as U-RNA, is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic cells.

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Small nucleolar RNA

Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs.

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Spliceosome

A spliceosome is a large and complex molecular machine found primarily within the splicing speckles of the cell nucleus of eukaryotic cells.

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Redirects here:

2'-O-ribose-methylation, 2'O-methylation, 2'O-ribose-methylation.

References

[1] https://en.wikipedia.org/wiki/2'-O-methylation

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