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NicVAX

Index NicVAX

NicVAX is an experimental conjugate vaccine intended to reduce or eliminate physical dependence to nicotine. [1]

24 relations: Antibody, Blood–brain barrier, Central nervous system, Circulatory system, Clinical Pharmacology & Therapeutics, Common cold, Conjugate vaccine, Dopamine, Hapten, Headache, Immune response, Immune system, Injection (medicine), Inoculation, Molecule, National Institute on Drug Abuse, Nicotine, Norepinephrine, Physical dependence, Placebo, Pseudomonas aeruginosa, Receptor (biochemistry), Respiratory tract, Smoking cessation.

Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

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Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Circulatory system

The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.

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Clinical Pharmacology & Therapeutics

Clinical Pharmacology & Therapeutics is a monthly peer-reviewed medical journal which covers research on the nature, action, efficacy, and evaluation of therapeutics.

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Common cold

The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory tract that primarily affects the nose.

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Conjugate vaccine

A conjugate vaccine is created by covalently attaching a poor antigen to a strong antigen thereby eliciting a stronger immunological response to the poor antigen.

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Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.

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Hapten

Haptens are minute molecules that elicit an immune response only when attached to a large carrier such as a protein; the carrier may be one that also does not elicit an immune response by itself.

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Headache

Headache is the symptom of pain anywhere in the region of the head or neck.

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Immune response

The Immune response is the body's response caused by its immune system being activated by antigens.

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Immune system

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.

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Injection (medicine)

Injection (often referred to as a "shot" in US English, or a "jab" in UK English) is the act of putting a liquid, especially a drug, into a person's body using a needle (usually a hypodermic needle) and a syringe.

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Inoculation

The terms inoculation, vaccination and immunization are often used synonymously to refer to artificial induction of immunity against various infectious diseases.

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Molecule

A molecule is an electrically neutral group of two or more atoms held together by chemical bonds.

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National Institute on Drug Abuse

The National Institute on Drug Abuse (NIDA) is a United States federal-government research institute whose mission is to "lead the Nation in bringing the power of science to bear on drug abuse and addiction." The institute has conducted an in-depth study of addiction according to its biological, behavioral and social components.

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Nicotine

Nicotine is a potent parasympathomimetic stimulant and an alkaloid found in the nightshade family of plants.

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Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.

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Physical dependence

Physical dependence is a physical condition caused by chronic use of a tolerance forming drug, in which abrupt or gradual drug withdrawal causes unpleasant physical symptoms.

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Placebo

A placebo is a substance or treatment of no intended therapeutic value.

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Pseudomonas aeruginosa

Pseudomonas aeruginosa is a common Gram-negative, rod-shaped bacterium that can cause disease in plants and animals, including humans.

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.

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Respiratory tract

In humans, the respiratory tract is the part of the anatomy of the respiratory system involved with the process of respiration.

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Smoking cessation

Smoking cessation (also known as quitting smoking or simply quitting) is the process of discontinuing tobacco smoking.

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Redirects here:

3′AmNic-rEPA, NicVax.

References

[1] https://en.wikipedia.org/wiki/NicVAX

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