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Directionality (molecular biology)

Index Directionality (molecular biology)

Directionality, in molecular biology and biochemistry, is the end-to-end chemical orientation of a single strand of nucleic acid. [1]

46 relations: Adenosine, Base pair, Binding site, Biochemistry, Complementarity (molecular biology), Deoxyribose, DNA, DNA ligase, DNA sequencing, Eukaryote, Exonuclease, Five prime untranslated region, Five-prime cap, Furanose, Gene, Hydroxy group, In vivo, Kozak consensus sequence, Messenger RNA, Methionine, Methylation, Molecular biology, Molecular cloning, Nucleic acid, Nucleic acid double helix, Nucleoside triphosphate, Nucleotide, Phosphatase, Phosphate, Phosphodiester bond, Plasmid, Polyadenylation, Polymerase, Promoter (genetics), Protein, Ribose, Ribosome, Ribosome-binding site, RNA, Sense (molecular biology), Start codon, Three prime untranslated region, Translation (biology), Upstream and downstream (DNA), 5' flanking region, 7-Methylguanosine.

Adenosine

Adenosine is both a chemical found in many living systems and a medication.

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Base pair

A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.

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Binding site

In biochemistry, a binding site is a region on a protein or piece of DNA or RNA to which ligands (specific molecules and/or ions) may form a chemical bond.

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Biochemistry

Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms.

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Complementarity (molecular biology)

In molecular biology, complementarity describes a relationship between two structures each following the lock-and-key principle.

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Deoxyribose

Deoxyribose, or more precisely 2-deoxyribose, is a monosaccharide with idealized formula H−(C.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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DNA ligase

DNA ligase is a specific type of enzyme, a ligase, that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.

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DNA sequencing

DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule.

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Eukaryote

Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).

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Exonuclease

Exonucleases are enzymes that work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain.

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Five prime untranslated region

The 5′ untranslated region (5′ UTR) (also known as a leader sequence or leader RNA) is the region of an mRNA that is directly upstream from the initiation codon.

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Five-prime cap

In molecular biology, the five-prime cap (5′ cap) is a specially altered nucleotide on the 5′ end of some primary transcripts such as precursor messenger RNA.

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Furanose

A furanose is a collective term for carbohydrates that have a chemical structure that includes a five-membered ring system consisting of four carbon atoms and one oxygen atom.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Hydroxy group

A hydroxy or hydroxyl group is the entity with the formula OH.

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In vivo

Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

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Kozak consensus sequence

The Kozak consensus sequence, Kozak consensus or Kozak sequence is a sequence which occurs on eukaryotic mRNA and has the consensus (gcc)gccRccAUGG.

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Messenger RNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

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Methionine

Methionine (symbol Met or M) is an essential amino acid in humans.

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Methylation

In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.

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Molecular biology

Molecular biology is a branch of biology which concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions.

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Molecular cloning

Molecular cloning is a set of experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms.

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Nucleic acid

Nucleic acids are biopolymers, or small biomolecules, essential to all known forms of life.

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Nucleic acid double helix

In molecular biology, the term double helix refers to the structure formed by double-stranded molecules of nucleic acids such as DNA.

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Nucleoside triphosphate

A nucleoside triphosphate is a molecule containing a nitrogenous base bound to a 5-carbon sugar (either ribose or deoxyribose), with three phosphate groups bound to the sugar.

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Nucleotide

Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.

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Phosphatase

A phosphatase is an enzyme that uses water to cleave a phosphoric acid monoester into a phosphate ion and an alcohol.

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Phosphate

A phosphate is chemical derivative of phosphoric acid.

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Phosphodiester bond

A phosphodiester bond occurs when exactly two of the hydroxyl groups in phosphoric acid react with hydroxyl groups on other molecules to form two ester bonds.

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Plasmid

A plasmid is a small DNA molecule within a cell that is physically separated from a chromosomal DNA and can replicate independently.

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Polyadenylation

Polyadenylation is the addition of a poly(A) tail to a messenger RNA.

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Polymerase

A polymerase is an enzyme (EC 2.7.7.6/7/19/48/49) that synthesizes long chains of polymers or nucleic acids.

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Promoter (genetics)

In genetics, a promoter is a region of DNA that initiates transcription of a particular gene.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Ribose

Ribose is a carbohydrate with the formula C5H10O5; specifically, it is a pentose monosaccharide (simple sugar) with linear form H−(C.

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Ribosome

The ribosome is a complex molecular machine, found within all living cells, that serves as the site of biological protein synthesis (translation).

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Ribosome-binding site

A ribosome binding site, or ribosomal binding site (RBS), is a sequence of nucleotides upstream of the start codon of an mRNA transcript that is responsible for the recruitment of a ribosome during the initiation of protein translation.

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RNA

Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.

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Sense (molecular biology)

In molecular biology and genetics, the sense of nucleic acid molecules (often DNA or RNA) is the nature of their roles and their complementary molecules' nucleic acid units' roles in specifying amino acids.

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Start codon

The start codon is the first codon of a messenger RNA (mRNA) transcript translated by a ribosome.

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Three prime untranslated region

In molecular genetics, the three prime untranslated region (3'-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon.

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Translation (biology)

In molecular biology and genetics, translation is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription of DNA to RNA in the cell's nucleus.

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Upstream and downstream (DNA)

In molecular biology and genetics, upstream and downstream both refer to relative positions of genetic code in DNA or RNA.

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5' flanking region

The 5' flanking region is a region of DNA that is adjacent to the 5' end of the gene.

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7-Methylguanosine

7-Methylguanosine (m7G) is a modified purine nucleoside.

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Redirects here:

3', 3' end, 3' flanking region, 3' to 5', 3'-end, 3’, 3′ end, 3′-end, 5', 5' end, 5' to 3', 5'-3', 5'-end, 5'-terminal, 5’ end, 5′ end, 5′-end, Five prime end, Three prime end.

References

[1] https://en.wikipedia.org/wiki/Directionality_(molecular_biology)

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