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20 relations: Agonist, Choleretic, Diarylpropionitrile, Enzyme, Estrogen, Estrogen receptor, Estrogen receptor alpha, Estrogen receptor beta, Flavanone, Glycyrrhiza uralensis, Isoflavonoid synthase, Liquorice, Menerba, Methylpiperidinopyrazole, Partial agonist, PHTPP, Prinaberel, Propylpyrazoletriol, WAY-200070, (R,R)-Tetrahydrochrysene.
Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
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Choleretic
Choleretics are substances that increase the volume of secretion of bile from the liver as well as the amount of solids secreted.
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Diarylpropionitrile
Diarylpropionitrile (DPN), also known as 2,3-bis(p-hydroxyphenyl)propionitrile (2,3-BHPPN), is a synthetic, nonsteroidal, and highly selective agonist of ERβ (IC50.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Estrogen
Estrogen, or oestrogen, is the primary female sex hormone.
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Estrogen receptor
Estrogen receptors (ERs) are a group of proteins found inside cells.
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Estrogen receptor alpha
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor that is activated by the sex hormone estrogen.
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Estrogen receptor beta
Estrogen receptor beta (ER-β), also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2), is one of two main types of estrogen receptor, a nuclear receptor which is activated by the sex hormone estrogen.
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Flavanone
The flavanones, a type of flavonoids, are various aromatic, colorless ketones derived from flavone that often occur in plants as glycosides.
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Glycyrrhiza uralensis
Glycyrrhiza uralensis, also known as Chinese liquorice, is a flowering plant native to Asia.
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Isoflavonoid synthase
2-hydroxyisoflavanone synthase (CYT93C, IFS, isoflavonoid synthase) is an enzyme with systematic name liquiritigenin,NADPH:oxygen oxidoreductase (hydroxylating, aryl migration).
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Liquorice
Liquorice (British English) or licorice (American English) is the root of Glycyrrhiza glabra from which a sweet flavour can be extracted.
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Menerba
Menerba, also known as Menopause Formula 101 (MF-101), is a botanical drug candidate that acts as a selective estrogen receptor modulator (SERM) which is being studied for its potential to relieve hot flashes associated with menopause.
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Methylpiperidinopyrazole
Methylpiperidinopyrazole (MPP) is a synthetic, nonsteroidal, and highly selective antagonist of ERα that is used in scientific research to study the function of this receptor.
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Partial agonist
In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.
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PHTPP
PHTPP is a synthetic, nonsteroidal, and highly selective antagonist of ERβ that is used in scientific research to study the function of this receptor.
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Prinaberel
Prinaberel (INN, USAN) (developmental code names ERB-041, WAY-202041) is a synthetic, nonsteroidal, and highly selective agonist of the ERβ subtype of the estrogen receptor.
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Propylpyrazoletriol
Propylpyrazoletriol (PPT) is a synthetic, nonsteroidal agonist of ERα with 400-fold selectivity over ERβ that is used widely in scientific research to study the function of ERα.
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WAY-200070
WAY-200070 is a synthetic, nonsteroidal, highly selective agonist of ERβ.
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(R,R)-Tetrahydrochrysene
(R,R)-Tetrahydrochrysene ((R,R)-THC) is a drug used to study the estrogen receptors (ERs) in scientific research.
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