Beta-Naphthoflavone

beta-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and as such is an inducer of such detoxification enzymes as cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). ^[1]

7 relations: Alpha-Naphthoflavone, Aryl hydrocarbon receptor, Chemoprophylaxis, Cytochrome P450, Detoxification, Enzyme, Glucuronosyltransferase.

Alpha-Naphthoflavone

alpha-Naphthoflavone, also known as 7,8-benzoflavone and 2-phenyl-benzo(h)chromen-4-one, is a synthetic flavone derivative.

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Aryl hydrocarbon receptor

The aryl hydrocarbon receptor (AhR or AHR or ahr or ahR) is a protein that in humans is encoded by the AHR gene.

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Chemoprophylaxis

Chemoprevention (also Chemoprophylaxis) refers to the administration of a medication for the purpose of preventing disease or infection.

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Cytochrome P450

Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.

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Detoxification

Detoxification or detoxication (detox for short) is the physiological or medicinal removal of toxic substances from a living organism, including the human body, which is mainly carried out by the liver.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Glucuronosyltransferase

Uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase, UGT) is a cytosolic glycosyltransferase that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule.

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Redirects here:

5,6-Benzoflavone, 5,6-benzoflavone, B-Naphthoflavone, Beta-naphthoflavone.

References

[1] https://en.wikipedia.org/wiki/Beta-Naphthoflavone

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