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7-OH-DPAT

7-OH-DPAT is a synthetic compound that acts as a dopamine receptor agonist with reasonable selectivity for the D3 receptor subtype, and low affinity for serotonin receptors, unlike its structural isomer 8-OH-DPAT. [1]

11 relations: Agonist, Biochemical Pharmacology, Cocaine, Dopamine receptor, Dopamine receptor D3, PD-128,907, Rotigotine, UH-232, 5-HT receptor, 5-OH-DPAT, 8-OH-DPAT.

Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Biochemical Pharmacology

Biochemical Pharmacology is a peer-reviewed medical journal published by Elsevier.

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Cocaine

Cocaine, also known as benzoylmethylecgonine or coke, is a strong stimulant mostly used as a recreational drug.

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Dopamine receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS).

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Dopamine receptor D3

D3 dopamine receptor is a protein that in humans is encoded by the DRD3 gene.

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PD-128,907

PD-128,907 is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D2 and D3 receptors.

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Rotigotine

Rotigotine (Neupro) is a dopamine agonist of the non-ergoline class of medications indicated for the treatment of Parkinson's disease (PD) and Willis-Ekbom Disease (WED) formerly known as restless legs syndrome (RLS) in Europe and the United States.

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UH-232

UH-232 ((+)-UH232) is a drug which acts as a subtype selective mixed agonist-antagonist for dopamine receptors, acting as a weak partial agonist at the D3 subtype, and an antagonist at D2Sh autoreceptors on dopaminergic nerve terminals.

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5-HT receptor

The serotonin receptors, also known as 5-hydroxytryptamine receptors or 5-HT receptors, are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems.

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5-OH-DPAT

5-OH-DPAT is a synthetic compound that acts as a dopamine receptor agonist with selectivity for the D2 receptor and D3 receptor subtypes.

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8-OH-DPAT

8-OH-DPAT is a research chemical of the aminotetralin chemical class which was developed in the 1980s and has been widely used to study the function of the 5-HT1A receptor.

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References

[1] https://en.wikipedia.org/wiki/7-OH-DPAT

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