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Deflazacort

Index Deflazacort

Deflazacort (trade name Emflaza or Calcort among others) is a glucocorticoid used as an anti-inflammatory and immunosuppressant. [1]

50 relations: Anaphylaxis, Anti-inflammatory, Asthma, Autoimmune hemolytic anemia, Betamethasone, Bone density, Bullous pemphigoid, Connective tissue disease, Corticosteroid, Cortisone, Crohn's disease, Cushing's syndrome, Dermatomyositis, Dexamethasone, Drug metabolism, Duchenne muscular dystrophy, Endocrine system, Esterase, Fast track (FDA), Food and Drug Administration, Glucocorticoid, Hydrocortisone, Hypersensitivity, Immune thrombocytopenic purpura, Immunosuppression, Immunosuppressive drug, Interstitial nephritis, Juvenile idiopathic arthritis, Kidney, Lymphoid leukemia, Lymphoma, Marathon Pharmaceuticals, Methylprednisolone, Multiple myeloma, Muscular dystrophy, Nephrotic syndrome, Oral administration, Pemphigus, Polyarteritis nodosa, Polymyalgia rheumatica, Prednisolone, Prednisone, Prodrug, Pyoderma gangrenosum, Rheumatoid arthritis, Sarcoidosis, Systemic lupus erythematosus, Therapeutic index, Triamcinolone, Ulcerative colitis.

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

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Anti-inflammatory

Anti-inflammatory, or antiinflammatory, refers to the property of a substance or treatment that reduces inflammation or swelling.

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Asthma

Asthma is a common long-term inflammatory disease of the airways of the lungs.

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Autoimmune hemolytic anemia

Autoimmune hemolytic anemia (or autoimmune haemolytic anaemia; AIHA) occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst (lyse), leading to an insufficient number of oxygen-carrying red blood cells in the circulation.

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Betamethasone

Betamethasone is a steroid medication.

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Bone density

Bone density, or bone mineral density (BMD), is the amount of bone mineral in bone tissue.

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Bullous pemphigoid

Bullous pemphigoid is an acute or chronic autoimmune skin disease, involving the formation of blisters, more appropriately known as bullae, at the space between the epidermis and dermis skin layers.

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Connective tissue disease

A connective tissue disease is any disease that has the connective tissues of the body as a target of pathology.

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Corticosteroid

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.

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Cortisone

Cortisone, also known as 17α,21-dihydroxypregn-4-ene-3,11,20-trione, is a pregnane (21-carbon) steroid hormone.

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Crohn's disease

Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.

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Cushing's syndrome

Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to cortisol.

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Dermatomyositis

Dermatomyositis (DM) is a long term inflammatory disorder which affects muscles.

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Dexamethasone

Dexamethasone is a type of corticosteroid medication.

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Drug metabolism

Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems.

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Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a severe type of muscular dystrophy.

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Endocrine system

The endocrine system is a chemical messenger system consisting of hormones, the group of glands of an organism that carry those hormones directly into the circulatory system to be carried towards distant target organs, and the feedback loops of homeostasis that the hormones drive.

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Esterase

An esterase is a hydrolase enzyme that splits esters into an acid and an alcohol in a chemical reaction with water called hydrolysis.

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Fast track (FDA)

Fast Track is a designation by the United States Food and Drug Administration (FDA) of an investigational drug for expedited review to facilitate development of drugs which treat a serious or life-threatening condition and fill an unmet medical need.

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Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

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Glucocorticoid

Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.

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Hydrocortisone

Hydrocortisone, sold under a number of brand names, is the name for the hormone cortisol when supplied as a medication.

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Hypersensitivity

Hypersensitivity (also called hypersensitivity reaction or intolerance) refers to undesirable reactions produced by the normal immune system, including allergies and autoimmunity.

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Immune thrombocytopenic purpura

Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia.

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Immunosuppression

Immunosuppression is a reduction of the activation or efficacy of the immune system.

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Immunosuppressive drug

Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system.

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Interstitial nephritis

Interstitial nephritis (or tubulo-interstitial nephritis) is a form of nephritis affecting the interstitium of the kidneys surrounding the tubules, i.e., is inflammation of the spaces between renal tubules.

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Juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA), also known as juvenile rheumatoid arthritis, is the most common form of arthritis in children and adolescents.

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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Lymphoid leukemia

Lymphoid leukemias — also called lymphocytic, lymphogenous, or lymphoblastic leukemias — are a group of leukemias affecting circulating lymphocytes, a type of white blood cells.

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Lymphoma

Lymphoma is a group of blood cancers that develop from lymphocytes (a type of white blood cell).

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Marathon Pharmaceuticals

Marathon Pharmaceuticals LLC was a privately held biopharmaceuticals company focused on drugs for people with rare diseases.

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Methylprednisolone

Methylprednisolone, sold under the brand names Depo-Medrol and Solu-Medrol among others, is a corticosteroid medication used to suppress the immune system and decrease inflammation.

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Multiple myeloma

Multiple myeloma, also known as plasma cell myeloma, is a cancer of plasma cells, a type of white blood cell normally responsible for producing antibodies.

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Muscular dystrophy

Muscular dystrophy (MD) is a group of muscle diseases that results in increasing weakening and breakdown of skeletal muscles over time.

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Nephrotic syndrome

Nephrotic syndrome is a collection of symptoms due to kidney damage.

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Oral administration

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Pemphigus

Pemphigus is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes.

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Polyarteritis nodosa

Polyarteritis nodosa (PAN), also known as panarteritis nodosa, periarteritis nodosa, Kussmaul disease, or Kussmaul-Maier disease, is a systemic necrotizing inflammation of blood vessels (vasculitis) affecting small- or medium-sized muscular arteries, typically involving the arteries of the kidneys and other internal organs but generally sparing the lungs' circulation.

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Polymyalgia rheumatica

Polymyalgia rheumatica (PMR) is a syndrome with pain or stiffness, usually in the neck, shoulders, upper arms, and hips, but which may occur all over the body.

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Prednisolone

Prednisolone is a steroid medication used to treat certain types of allergies, inflammatory conditions, autoimmune disorders, and cancers.

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Prednisone

Prednisone is a synthetic glucocorticoid drug that is mostly used to suppress the immune system.

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Prodrug

A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.

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Pyoderma gangrenosum

Pyoderma gangrenosum is a condition that causes tissue to become necrotic, causing deep ulcers that usually occur on the legs.

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Rheumatoid arthritis

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.

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Sarcoidosis

Sarcoidosis is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomas.

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Systemic lupus erythematosus

Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.

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Therapeutic index

The therapeutic index (TI; also referred to as therapeutic ratio) is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxicity.

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Triamcinolone

Triamcinolone is an intermediate-acting synthetic glucocorticoid given orally, by injection, by inhalation, or as a topical ointment or cream.

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Ulcerative colitis

Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum.

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Redirects here:

ATC code H02AB13, ATCvet code QH02AB13, Azacort, C25H31NO6, Calcort, Emflaza, Zasix.

References

[1] https://en.wikipedia.org/wiki/Deflazacort

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