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Beta-1 adrenergic receptor

Index Beta-1 adrenergic receptor

The beta-1 adrenergic receptor (β1 adrenoceptor), also known as ADRB1, is a beta-adrenergic receptor, and also denotes the human gene encoding it. [1]

57 relations: Acebutolol, Adenylyl cyclase, Adipose tissue, Adrenaline, Adrenergic receptor, Agonist, Alpha-1 adrenergic receptor, Alpha-2 adrenergic receptor, Amylase, Angina, Antidepressant, Atenolol, Atrioventricular node, Atrium (heart), Beta blocker, Beta-2 adrenergic receptor, Beta-3 adrenergic receptor, Betaxolol, Bisoprolol, Cardiac action potential, Cardiac muscle, Cardiac output, Cardiac stimulant, Cardiogenic shock, Cerebral cortex, Chronotropic, Coronary artery disease, Cyclic adenosine monophosphate, Denopamine, DLG4, Dobutamine, Esmolol, G protein–coupled receptor, Gene, GIPC1, Glaucoma, Gs alpha subunit, Heart arrhythmia, Heart failure, Heart rate, Heterotrimeric G protein, Hypertension, Inotrope, Isoprenaline, Juxtaglomerular cell, Lipolysis, Metoprolol, Myocardial infarction, Nebivolol, Norepinephrine, ..., Protein–protein interaction, Renin, Salivary gland, Sinoatrial node, Ventricle (heart), Vortioxetine, Xamoterol. Expand index (7 more) »

Acebutolol

Acebutolol (trade names Sectral, Prent) is a beta blocker for the treatment of hypertension and arrhythmias.

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Adenylyl cyclase

Adenylyl cyclase (also commonly known as adenyl cyclase and adenylate cyclase, abbreviated AC) is an enzyme with key regulatory roles in essentially all cells.

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Adipose tissue

In biology, adipose tissue, body fat, or simply fat is a loose connective tissue composed mostly of adipocytes.

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Adrenaline

Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.

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Adrenergic receptor

The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline).

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Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Alpha-1 adrenergic receptor

The alpha-1 (α1) adrenergic receptor is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G-protein.

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Alpha-2 adrenergic receptor

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.

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Amylase

An amylase is an enzyme that catalyses the hydrolysis of starch into sugars.

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Angina

Angina, also known as angina pectoris, is chest pain or pressure, usually due to not enough blood flow to the heart muscle.

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Antidepressant

Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.

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Atenolol

Atenolol is a selective β1 receptor antagonist, a drug belonging to the group of beta blockers (sometimes written β-blockers), a class of drugs used primarily in cardiovascular diseases.

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Atrioventricular node

The atrioventricular node, or AV node is a part of the electrical conduction system of the heart that coordinates the top of the heart.

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Atrium (heart)

The atrium is the upper chamber in which blood enters the heart.

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Beta blocker

Beta blockers, also written β-blockers, are a class of medications that are particularly used to manage abnormal heart rhythms, and to protect the heart from a second heart attack (myocardial infarction) after a first heart attack (secondary prevention).

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Beta-2 adrenergic receptor

The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that interacts with (binds) epinephrine, a hormone and neurotransmitter (ligand synonym, adrenaline) whose signaling, via a downstream L-type calcium channel interaction, mediates physiologic responses such as smooth muscle relaxation and bronchodilation.

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Beta-3 adrenergic receptor

The beta-3 adrenergic receptor (β3 adrenoreceptor), also known as ADRB3, is a beta-adrenergic receptor, and also denotes the human gene encoding it.

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Betaxolol

Betaxolol (trade names Betoptic, Betoptic S, Lokren, Kerlone) is a selective beta1 receptor blocker used in the treatment of hypertension and glaucoma.

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Bisoprolol

Bisoprolol, marketed under the tradename Zebeta among others, is a medication most commonly used for heart diseases.

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Cardiac action potential

The cardiac action potential is a brief change in voltage (membrane potential) across the cell membrane of heart cells.

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Cardiac muscle

Cardiac muscle (heart muscle) is one of the three major types of muscle, the others being skeletal and smooth muscle.

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Cardiac output

Cardiac output (CO, also denoted by the symbols Q and \dot Q_), is a term used in cardiac physiology that describes the volume of blood being pumped by the heart, in particular by the left or right ventricle, per unit time.

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Cardiac stimulant

A cardiac stimulant is a substance which acts as a stimulant of the heart – e.g., via positive chronotropic or inotropic action.

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Cardiogenic shock

Cardiogenic shock is a medical emergency resulting from inadequate blood flow due to the dysfunction of the ventricles of the heart.

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Cerebral cortex

The cerebral cortex is the largest region of the cerebrum in the mammalian brain and plays a key role in memory, attention, perception, cognition, awareness, thought, language, and consciousness.

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Chronotropic

Chronotropic effects (from chrono-, meaning time, and tropos, "a turn") are those that change the heart rate.

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Coronary artery disease

Coronary artery disease (CAD), also known as ischemic heart disease (IHD), refers to a group of diseases which includes stable angina, unstable angina, myocardial infarction, and sudden cardiac death.

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Cyclic adenosine monophosphate

Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger important in many biological processes.

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Denopamine

Denopamine (INN) is a cardiotonic drug which acts as a β1 adrenergic receptor agonist.

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DLG4

PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (discs large homolog 4) gene.

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Dobutamine

Dobutamine is a sympathomimetic drug used in the treatment of heart failure and cardiogenic shock.

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Esmolol

Esmolol (trade name Brevibloc) is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.

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G protein–coupled receptor

G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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GIPC1

GIPC PDZ domain containing family, member 1 (GIPC1) is a protein that in humans is encoded by the GIPC1 gene.

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Glaucoma

Glaucoma is a group of eye diseases which result in damage to the optic nerve and vision loss.

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Gs alpha subunit

The Gs alpha subunit (Gαs, Gsα, or Gs protein) is a heterotrimeric G protein subunit that activates the cAMP-dependent pathway by activating adenylyl cyclase.

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Heart arrhythmia

Heart arrhythmia (also known as arrhythmia, dysrhythmia, or irregular heartbeat) is a group of conditions in which the heartbeat is irregular, too fast, or too slow.

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Heart failure

Heart failure (HF), often referred to as congestive heart failure (CHF), is when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.

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Heart rate

Heart rate is the speed of the heartbeat measured by the number of contractions of the heart per minute (bpm).

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Heterotrimeric G protein

"G protein" usually refers to the membrane-associated heterotrimeric G proteins, sometimes referred to as the "large" G proteins (as opposed to the subclass of smaller, monomeric small GTPases).

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Hypertension

Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

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Inotrope

An inotrope is an agent that alters the force or energy of muscular contractions.

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Isoprenaline

Isoprenaline, or isoproterenol, is a medication used for the treatment of bradycardia (slow heart rate), heart block, and rarely for asthma.

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Juxtaglomerular cell

The juxtaglomerular cells (JG cells, or granular cells) are cells in the kidney that synthesize, store, and secrete the enzyme renin.

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Lipolysis

Lipolysis is the breakdown of lipids and involves hydrolysis of triglycerides into glycerol and free fatty acids.

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Metoprolol

Metoprolol, marketed under the tradename Lopressor among others, is a medication of the selective β1 receptor blocker type.

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Myocardial infarction

Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.

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Nebivolol

Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and, in Europe, also for left ventricular failure.

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Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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Renin

Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that mediates the volume of extracellular fluid (blood plasma, lymph and interstitial fluid), and arterial vasoconstriction.

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Salivary gland

The salivary glands in mammals are exocrine glands that produce saliva through a system of ducts.

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Sinoatrial node

The sinoatrial node (SA node), also known as sinus node, is a group of cells located in the wall of the right atrium of the heart.

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Ventricle (heart)

A ventricle is one of two large chambers in the heart that collect and expel blood received from an atrium towards the peripheral beds within the body and lungs.

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Vortioxetine

Vortioxetine is an antidepressant medication that is prescribed to treat depression.

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Xamoterol

Xamoterol is a cardiac stimulant.

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Redirects here:

ADRB1, ADRB1 (gene), Adrb1, Alpha-B1 adrenergic receptor, B1 adrenergic receptor, B1 receptor, Beta 1 receptor, Beta-1 adrenoceptor, Beta-1 agonist, Beta-1 receptor, Β1 adrenergic receptor, Β1 adrenoreceptor, Β1 receptor, Β1-Adrenergic receptor, Β1-adrenergic, Β1-adrenergic receptor, Β1-adrenoreceptor.

References

[1] https://en.wikipedia.org/wiki/Beta-1_adrenergic_receptor

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