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Befiradol

Befiradol (F-13,640; NLX-112) is a very potent and highly selective 5-HT1A receptor full agonist. [1]

17 relations: Adverse effect, Agonist, Allodynia, Analgesic, Benzothiophene, Binding selectivity, Drug tolerance, Eptapirone, F-15,599, Flesinoxan, Laboratoires Pierre Fabre, Levodopa-induced dyskinesia, Neurolixis, Opioid, Parkinson's disease, Potency (pharmacology), 5-HT1A receptor.

Adverse effect

In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery.

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Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Allodynia

Allodynia (Ancient Greek άλλος állos "other" and οδύνη odúnē "pain") refers to central pain sensitization (increased response of neurons) following painful, often repetitive, stimulation.

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Analgesic

An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.

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Benzothiophene

Benzothiophene is an aromatic organic compound with a molecular formula C8H6S and an odor similar to naphthalene (mothballs).

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Binding selectivity

Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

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Drug tolerance

Drug tolerance is a pharmacology concept where a subject's reaction to a specific drug and concentration of the drug is reduced followed repeated use, requiring an increase in concentration to achieve the desired effect.

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Eptapirone

Eptapirone (F-11,440) is a very potent and highly selective 5-HT1A receptor full agonist of the azapirone family.

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F-15,599

F-15,599, also known as NLX-101, is a very potent and highly selective 5-HT1A receptor full agonist.

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Flesinoxan

Flesinoxan (DU-29,373) is a potent and selective 5-HT1A receptor partial/near-full agonist of the phenylpiperazine class.

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Laboratoires Pierre Fabre

Laboratoires Pierre Fabre is a French multinational pharmaceutical and cosmetics company.

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Levodopa-induced dyskinesia

Levodopa-induced dyskinesia is a form of dyskinesia associated with levodopa used to treat Parkinson's disease.

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Neurolixis

Neurolixis is a biopharmaceutical company focused on novel drugs for the treatment of human central nervous system diseases.

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Opioid

An "opioid" is any synthetic narcotic not derived from opium.

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Parkinson's disease

Parkinson's disease (PD, also known as idiopathic or primary parkinsonism, hypokinetic rigid syndrome (HRS), or paralysis agitans) is a degenerative disorder of the central nervous system mainly affecting the motor system.

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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5-HT1A receptor

The 5-HT1A receptor is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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Redirects here:

C20H22ClF2N3O, F 13640, F-13,640, F-13640, F13640.

References

[1] https://en.wikipedia.org/wiki/Befiradol

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