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Bilirubin

Index Bilirubin

Bilirubin is a yellow compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates. [1]

75 relations: Alanine transaminase, Albumin, Alkaline phosphatase, Antipsychotic, Aspartate transaminase, Azobilirubin, Babesiosis, Basal ganglia, Beta-glucuronidase, Bile, Bile acid, Biliary atresia, Bilirubin diglucuronide, Biliverdin, Biliverdin reductase, Blood film, Blood–brain barrier, Bruise, Catabolism, Chemotherapy, Cirrhosis, Cis–trans isomerism, Common bile duct stone, Crigler–Najjar syndrome, Dubin–Johnson syndrome, Enterohepatic circulation, Enzyme, Epileptic seizure, Feces, Gamma-glutamyltransferase, Gilbert's syndrome, Glucuronic acid, Glucuronidation, Glucuronosyltransferase, Heme, Hemoglobin, Hemolysis, Hemolytic anemia, Hepatitis, Hy's law, Ileum, International System of Units, Jaundice, Kernicterus, Large intestine, Light therapy, Liver function tests, Medical laboratory, Medication, Neonatal jaundice, ..., Phycobilin, Phytochrome, Pigment, Porphyrin, Primary biliary cholangitis, Primary sclerosing cholangitis, Pyrimethamine, Pyrrole, Red blood cell, Reference ranges for blood tests, Reflex, Rotor syndrome, Rudolf Virchow, Sclera, Sex steroid, Stercobilin, Sulfonamide (medicine), Tetrapyrrole, Toxoplasmosis, Urine, Urobilin, Urobilinogen, Van den Bergh reaction, Vertebrate, WebMD. Expand index (25 more) »

Alanine transaminase

Alanine transaminase (ALT) is a transaminase enzyme.

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Albumin

The albumins (formed from Latin: albumen "(egg) white; dried egg white") are a family of globular proteins, the most common of which are the serum albumins.

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Alkaline phosphatase

Alkaline phosphatase (ALP, ALKP, ALPase, Alk Phos) or basic phosphatase is a homodimeric protein enzyme of 86 kilodaltons.

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Antipsychotic

Antipsychotics, also known as neuroleptics or major tranquilizers, are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder.

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Aspartate transaminase

Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or serum glutamic oxaloacetic transaminase (SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme that was first described by Arthur Karmen and colleagues in 1954.

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Azobilirubin

Azobilirubin is a red-violet compound formed by the condensation of diazotized sulfanilic acid with bilirubin in the van den Bergh reaction.

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Babesiosis

Babesiosis is a malaria-like parasitic disease caused by infection with Babesia, a genus of Apicomplexa.

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Basal ganglia

The basal ganglia (or basal nuclei) is a group of subcortical nuclei, of varied origin, in the brains of vertebrates including humans, which are situated at the base of the forebrain.

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Beta-glucuronidase

Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze breakdown of complex carbohydrates.

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Bile

Bile or gall is a dark green to yellowish brown fluid, produced by the liver of most vertebrates, that aids the digestion of lipids in the small intestine.

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Bile acid

Bile acids are steroid acids found predominantly in the bile of mammals and other vertebrates.

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Biliary atresia

Biliary atresia, also known as extrahepatic ductopenia and progressive obliterative cholangiopathy, is a childhood disease of the liver in which one or more bile ducts are abnormally narrow, blocked, or absent.

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Bilirubin diglucuronide

Bilirubin diglucuronide is a conjugated form of bilirubin formed in bilirubin metabolism.

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Biliverdin

Biliverdin is a green tetrapyrrolic bile pigment, and is a product of heme catabolism.

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Biliverdin reductase

Biliverdin reductase (BVR) is an enzyme found in all tissues under normal conditions, but especially in reticulo-macrophages of the liver and spleen.

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Blood film

A blood film—or peripheral blood smear—is a thin layer of blood smeared on a glass microscope slide and then stained in such a way as to allow the various blood cells to be examined microscopically.

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Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).

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Bruise

A contusion, commonly known as a bruise, is a type of hematoma of tissue in which capillaries and sometimes venules are damaged by trauma, allowing blood to seep, hemorrhage, or extravasate into the surrounding interstitial tissues.

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Catabolism

Catabolism (from Greek κάτω kato, "downward" and βάλλειν ballein, "to throw") is the set of metabolic pathways that breaks down molecules into smaller units that are either oxidized to release energy or used in other anabolic reactions.

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Chemotherapy

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Cirrhosis

Cirrhosis is a condition in which the liver does not function properly due to long-term damage.

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Cis–trans isomerism

Cis–trans isomerism, also known as geometric isomerism or configurational isomerism, is a term used in organic chemistry.

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Common bile duct stone

Common bile duct stone, also known as choledocholithiasis, is the presence of gallstones in the common bile duct (thus choledocho- + lithiasis).

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Crigler–Najjar syndrome

Crigler–Najjar syndrome or CNS is a rare inherited disorder affecting the metabolism of bilirubin, a chemical formed from the breakdown of the heme in red blood cells.

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Dubin–Johnson syndrome

Dubin–Johnson syndrome (DJS) is a rare, autosomal recessive, benign disorder that causes an isolated increase of conjugated bilirubin in the serum.

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Enterohepatic circulation

Enterohepatic circulation refers to the circulation of biliary acids, bilirubin, drugs or other substances from the liver to the bile, followed by entry into the small intestine, absorption by the enterocyte and transport back to the liver.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Epileptic seizure

An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.

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Feces

Feces (or faeces) are the solid or semisolid remains of the food that could not be digested in the small intestine.

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Gamma-glutamyltransferase

Gamma-glutamyltransferase (also γ-glutamyltransferase, GGT, gamma-GT) is a transferase (a type of enzyme) that catalyzes the transfer of gamma-glutamyl functional groups from molecules such as glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate).

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Gilbert's syndrome

Gilbert's syndrome (GS) is a mild liver disorder in which the liver does not properly process bilirubin.

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Glucuronic acid

Glucuronic acid (from Greek γλυκύς "sweet" and οὖρον "urine") is a uronic acid that was first isolated from urine (hence the name).

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Glucuronidation

Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids.

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Glucuronosyltransferase

Uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase, UGT) is a cytosolic glycosyltransferase that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule.

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Heme

Heme or haem is a coordination complex "consisting of an iron ion coordinated to a porphyrin acting as a tetradentate ligand, and to one or two axial ligands." The definition is loose, and many depictions omit the axial ligands.

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Hemoglobin

Hemoglobin (American) or haemoglobin (British); abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates (with the exception of the fish family Channichthyidae) as well as the tissues of some invertebrates.

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Hemolysis

Hemolysis or haemolysis, also known by several other names, is the rupturing (lysis) of red blood cells (erythrocytes) and the release of their contents (cytoplasm) into surrounding fluid (e.g. blood plasma).

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Hemolytic anemia

Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular, but usually in the spleen).

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Hepatitis

Hepatitis is inflammation of the liver tissue.

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Hy's law

Hy's law is a rule of thumb that a patient is at high risk of a fatal drug-induced liver injury (DILI) if given a medication that causes hepatocellular injury (not cholestatic injury) with jaundice.

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Ileum

The ileum is the final section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds.

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International System of Units

The International System of Units (SI, abbreviated from the French Système international (d'unités)) is the modern form of the metric system, and is the most widely used system of measurement.

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Jaundice

Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and whites of the eyes due to high bilirubin levels.

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Kernicterus

Kernicterus is a bilirubin-induced brain dysfunction.

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Large intestine

The large intestine, also known as the large bowel or colon, is the last part of the gastrointestinal tract and of the digestive system in vertebrates.

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Light therapy

Light therapy—or phototherapy, classically referred to as heliotherapy—consists of exposure to daylight or to specific wavelengths of light using polychromatic polarised light, lasers, light-emitting diodes, fluorescent lamps, dichroic lamps or very bright, full-spectrum light.

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Liver function tests

Liver function tests (LFTs or LFs) are groups of blood tests that give information about the state of a patient's liver.

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Medical laboratory

A medical laboratory or clinical laboratory is a laboratory where tests are carried out on clinical specimens in order to obtain information about the health of a patient in order to provide diagnosis, treatment, and prevention of disease.

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Medication

A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Neonatal jaundice

Neonatal jaundice is a yellowish discoloration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels.

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Phycobilin

Phycobilins (from Greek: φύκος (phykos) meaning "alga", and from Latin: bilis meaning "bile") are light-capturing bilins found in cyanobacteria and in the chloroplasts of red algae, glaucophytes and some cryptomonads (though not in green algae and plants).

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Phytochrome

Phytochromes are a class of photoreceptor in plants, bacteria and fungi use to detect light.

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Pigment

A pigment is a material that changes the color of reflected or transmitted light as the result of wavelength-selective absorption.

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Porphyrin

Porphyrins (/phɔɹfɚɪn/ ''POUR-fer-in'') are a group of heterocyclic macrocycle organic compounds, composed of four modified pyrrole subunits interconnected at their α carbon atoms via methine bridges (.

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Primary biliary cholangitis

Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver.

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Primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is a long-term progressive disease of the liver and gallbladder characterized by inflammation and scarring of the bile ducts which normally allow bile to drain from the gallbladder.

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Pyrimethamine

Pyrimethamine, sold under the trade name Daraprim, is a medication used with leucovorin to treat toxoplasmosis and cystoisosporiasis.

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Pyrrole

Pyrrole is a heterocyclic aromatic organic compound, a five-membered ring with the formula C4H4NH.

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Red blood cell

Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.

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Reference ranges for blood tests

Reference ranges for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples.

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Reflex

A reflex, or reflex action, is an involuntary and nearly instantaneous movement in response to a stimulus.

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Rotor syndrome

Rotor syndrome, also called Rotor type hyperbilirubinemia, is a rare, relatively benign autosomal recessive bilirubin disorder.

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Rudolf Virchow

Rudolf Ludwig Carl Virchow (13 October 1821 – 5 September 1902) was a German physician, anthropologist, pathologist, prehistorian, biologist, writer, editor, and politician, known for his advancement of public health.

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Sclera

The sclera, also known as the white of the eye, is the opaque, fibrous, protective, outer layer of the human eye containing mainly collagen and some elastic fiber.

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Sex steroid

Sex steroids, also known as gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors.

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Stercobilin

Stercobilin is a tetrapyrrolic bile pigment and is one end-product of heme catabolism.

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Sulfonamide (medicine)

Sulfonamide (also called sulphonamide, sulfa drugs or sulpha drugs) is the basis of several groups of drugs.

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Tetrapyrrole

Tetrapyrroles are a class of chemical compounds that contain four pyrrole or pyrrole-like rings.

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Toxoplasmosis

Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii.

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Urine

Urine is a liquid by-product of metabolism in humans and in many animals.

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Urobilin

Urobilin or urochrome is the chemical primarily responsible for the yellow color of urine.

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Urobilinogen

Urobilinogen is a colorless by-product of bilirubin reduction.

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Van den Bergh reaction

Van den Bergh reaction is a chemical reaction used to measure bilirubin levels in blood.

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Vertebrate

Vertebrates comprise all species of animals within the subphylum Vertebrata (chordates with backbones).

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WebMD

WebMD is an American corporation known primarily as an online publisher of news and information pertaining to human health and well-being.

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Redirects here:

Bilifulvin, Biliphaein, Bilirubin (data page), Bilirubin metabolism, Billirubin, Billy Rubin, C33H36N4O6, Cholepyrrhin, Conjugated bilirubin, Direct bilirubin, Haematoidin, Hematoidin, High bilirubin, Hyperbilirubinemia, Indirect bilirubin, Total bilirubin, Unconjugated bilirubin.

References

[1] https://en.wikipedia.org/wiki/Bilirubin

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