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Bromazepam

Index Bromazepam

Bromazepam (marketed under several brand names, including Lectopam, Lexotan, Lexilium, Lexaurin, Brazepam, Rekotnil, Bromaze, Somalium and Lexotanil) is a benzodiazepine derivative drug, patented by Roche in 1963 and developed clinically in the 1970s. [1]

65 relations: Anterograde amnesia, Anxiety, Anxiolytic, Ataxia, Benzene, Benzodiazepine, Benzodiazepine dependence, Benzodiazepine overdose, Benzodiazepine withdrawal syndrome, Biological half-life, Breastfeeding, Cannabis, Cimetidine, Clonazepam, Clorazepate, Comorbidity, Convention on Psychotropic Substances, CYP2D6, CYP3A4, Cytochrome P450, Delirium tremens, Derealization, Diazepam, Diazepine, Dysphoria, Dystonia, Ethanol, Flurazepam, Fluvoxamine, France, GABAA receptor, Gamma-Aminobutyric acid, Hoffmann-La Roche, Homicide, Itraconazole, Kidney, Leukopenia, Libido, Lipophilicity, Liver, Lorazepam, Mental disorder, Myalgia, Nitrazepam, Nitrogen, Nordazepam, Norepinephrine, Oxazepam, Physical dependence, Pregnancy category, ..., Propranolol, Pyridine, Rebound effect, Robbery, Sexual assault, Somnolence, Status epilepticus, Substance dependence, Sudden infant death syndrome, Tablet (pharmacy), Tachycardia, United States, Volume of distribution, Weesp, Working memory. Expand index (15 more) »

Anterograde amnesia

Anterograde amnesia is a loss of the ability to create new memories after the event that caused the amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact.

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Anxiety

Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behaviour such as pacing back and forth, somatic complaints, and rumination.

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Anxiolytic

An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.

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Ataxia

Ataxia is a neurological sign consisting of lack of voluntary coordination of muscle movements that includes gait abnormality.

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Benzene

Benzene is an important organic chemical compound with the chemical formula C6H6.

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Benzodiazepine

Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

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Benzodiazepine dependence

Benzodiazepine dependence or benzodiazepine addiction is when one has developed one or more of either tolerance, withdrawal symptoms, drug seeking behaviors, such as continued use despite harmful effects, and maladaptive pattern of substance use, according to the DSM-IV.

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Benzodiazepine overdose

Benzodiazepine overdose describes the ingestion of one of the drugs in the benzodiazepine class in quantities greater than are recommended or generally practiced.

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Benzodiazepine withdrawal syndrome

Benzodiazepine withdrawal syndrome—often abbreviated to benzo withdrawal—is the cluster of symptoms that emerge when a person who has taken benzodiazepines, either medically or recreationally, and has developed a physical dependence undergoes dosage reduction or discontinuation.

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Biological half-life

The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.

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Breastfeeding

Breastfeeding, also known as nursing, is the feeding of babies and young children with milk from a woman's breast.

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Cannabis

Cannabis is a genus of flowering plants in the family Cannabaceae.

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Cimetidine

Cimetidine, sold under the brand name Tagamet among others, is a histamine H2 receptor antagonist that inhibits stomach acid production.

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Clonazepam

Clonazepam, sold under the brand name Klonopin among others, is a medication used to prevent and treat seizures, panic disorder, and for the movement disorder known as akathisia.

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Clorazepate

Clorazepate, sold under the brand names Tranxene among others, is a benzodiazepine medication.

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Comorbidity

In medicine, comorbidity is the presence of one or more additional diseases or disorders co-occurring with (that is, concomitant or concurrent with) a primary disease or disorder; in the countable sense of the term, a comorbidity (plural comorbidities) is each additional disorder or disease.

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Convention on Psychotropic Substances

The Convention on Psychotropic Substances of 1971 is a United Nations treaty designed to control psychoactive drugs such as amphetamine-type stimulants, barbiturates, benzodiazepines, and psychedelics signed in Vienna, Austria on 21 February 1971.

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CYP2D6

Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.

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CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.

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Cytochrome P450

Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.

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Delirium tremens

Delirium tremens (DTs) is a rapid onset of confusion usually caused by withdrawal from alcohol.

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Derealization

Derealization (sometimes abbreviated as DR) is an alteration in the perception or experience of the external world so that it seems unreal.

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Diazepam

Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that typically produces a calming effect.

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Diazepine

Diazepine is a seven-membered heterocyclic compound with two nitrogen atoms (e.g., in ring positions 1 and 2).

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Dysphoria

Dysphoria (from δύσφορος (dysphoros), δυσ-, difficult, and φέρειν, to bear) is a profound state of unease or dissatisfaction.

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Dystonia

Dystonia is a neurological movement disorder syndrome in which sustained or repetitive muscle contractions result in twisting and repetitive movements or abnormal fixed postures.

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Ethanol

Ethanol, also called alcohol, ethyl alcohol, grain alcohol, and drinking alcohol, is a chemical compound, a simple alcohol with the chemical formula.

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Flurazepam

Flurazepam (marketed under the brand names Dalmane and Dalmadorm) is a drug which is a benzodiazepine derivative.

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Fluvoxamine

Fluvoxamine, sold under the brand name Luvox among others, is a medication which is used primarily for the treatment of obsessive–compulsive disorder (OCD), and is also used to treat major depressive disorder and anxiety disorders such as panic disorder and post-traumatic stress disorder.

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France

France, officially the French Republic (République française), is a sovereign state whose territory consists of metropolitan France in Western Europe, as well as several overseas regions and territories.

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GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

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Gamma-Aminobutyric acid

gamma-Aminobutyric acid, or γ-aminobutyric acid, or GABA, is the chief inhibitory neurotransmitter in the mammalian central nervous system.

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Hoffmann-La Roche

F.

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Homicide

Homicide is the act of one human killing another.

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Itraconazole

Itraconazole is an antifungal medication used to treat a number of fungal infections.

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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Leukopenia

Leukopenia is a decrease in the number of white blood cells (leukocytes) found in the blood, which places individuals at increased risk of infection.

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Libido

Libido, colloquially known as sex drive, is a person's overall sexual drive or desire for sexual activity.

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Lipophilicity

Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Lorazepam

Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication.

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Mental disorder

A mental disorder, also called a mental illness or psychiatric disorder, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning.

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Myalgia

Myalgia, or muscle pain, is a symptom of many diseases and disorders.

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Nitrazepam

Nitrazepam (brand names Alodorm and Mogadon, among others) is a hypnotic drug of the benzodiazepine class used for short-term relief from severe, disabling anxiety and insomnia.

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Nitrogen

Nitrogen is a chemical element with symbol N and atomic number 7.

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Nordazepam

Nordazepam (INN; marketed under brand names Nordaz, Stilny, Madar, Vegesan, and Calmday; also known as nordiazepam, desoxydemoxepam, and desmethyldiazepam) is a 1,4-benzodiazepine derivative.

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Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.

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Oxazepam

Oxazepam is a short-to-intermediate-acting benzodiazepine.

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Physical dependence

Physical dependence is a physical condition caused by chronic use of a tolerance forming drug, in which abrupt or gradual drug withdrawal causes unpleasant physical symptoms.

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Pregnancy category

The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy.

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Propranolol

Propranolol, sold under the brand name Inderal among others, is a medication of the beta blocker type. It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors. It is used to prevent migraine headaches, and to prevent further heart problems in those with angina or previous heart attacks. It can be taken by mouth or by injection into a vein. The formulation that is taken by mouth comes in short-acting and long-acting versions. Propranolol appears in the blood after 30 minutes and has a maximum effect between 60 and 90 minutes when taken by mouth. Common side effects include nausea, abdominal pain, and constipation. It should not be used in those with an already slow heart rate and most of those with heart failure. Quickly stopping the medication in those with coronary artery disease may worsen symptoms. It may worsen the symptoms of asthma. Caution is recommended in those with liver or kidney problems. Propranolol may cause harmful effects in the baby if taken during pregnancy. Its use during breastfeeding is probably safe, but the baby should be monitored for side effects. It is a non-selective beta blocker which works by blocking β-adrenergic receptors. Propranolol was discovered in 1964. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Propranolol is available as a generic medication. The wholesale cost in the developing world is between 0.24 and 2.16 per month as of 2014. In the United States it costs about $15 per month at a typical dose.

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Pyridine

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N.

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Rebound effect

The rebound effect, or rebound phenomenon, is the emergence or re-emergence of symptoms that were either absent or controlled while taking a medication, but appear when that same medication is discontinued, or reduced in dosage.

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Robbery

Robbery is the crime of taking or attempting to take anything of value by force, threat of force, or by putting the victim in fear.

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Sexual assault

Sexual assault is an act in which a person coerces or physically forces a person to engage in a sexual act against their will.

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Somnolence

Somnolence (alternatively "sleepiness" or "drowsiness") is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).

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Status epilepticus

Status epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them.

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Substance dependence

Substance dependence also known as drug dependence is an adaptive state that develops from repeated drug administration, and which results in withdrawal upon cessation of drug use.

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Sudden infant death syndrome

Sudden infant death syndrome (SIDS), also known as cot death or crib death, is the sudden unexplained death of a child less than one year of age.

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Tablet (pharmacy)

A tablet is a pharmaceutical dosage form.

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Tachycardia

Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.

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United States

The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.

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Volume of distribution

In pharmacology, the volume of distribution (VD, also known as apparent volume of distribution) is the theoretical volume that would be necessary to contain the total amount of an administered drug at the same concentration that it is observed in the blood plasma.

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Weesp

Weesp is a city and municipality in the province of North Holland, Netherlands.

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Working memory

Working memory is a cognitive system with a limited capacity that is responsible for temporarily holding information available for processing.

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Redirects here:

ATC code N05BA08, ATCvet code QN05BA08, Anxyrex, Apo-Bromazepam, Bromazepan, Calmepam, Compedium, Creosedin, Durazanil, Gen-Bromazepam, Lectopam, Lekotam, Lexatin, Lexaurin, Lexilium, Lexomil, Lexotan, Lexotanil, Normoc, Novo-bromazepam, Nu-Bromazepam, Somalium, Ultramidol.

References

[1] https://en.wikipedia.org/wiki/Bromazepam

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