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20 relations: Action potential, Allele, Alpha helix, Alternative splicing, Drosophila melanogaster, Epilepsy, Epileptic seizure, Exon, Generalized epilepsy with febrile seizures plus, Homology (biology), Mature messenger RNA, Membrane potential, Nav1.1, Nav1.2, RNA editing, SCN8A, Sodium, Sodium channel, Three prime untranslated region, Voltage-gated ion channel.
Action potential
In physiology, an action potential occurs when the membrane potential of a specific axon location rapidly rises and falls: this depolarisation then causes adjacent locations to similarly depolarise.
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Allele
An allele is a variant form of a given gene.
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Alpha helix
The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.
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Alternative splicing
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
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Drosophila melanogaster
Drosophila melanogaster is a species of fly (the taxonomic order Diptera) in the family Drosophilidae.
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Epilepsy
Epilepsy is a group of neurological disorders characterized by epileptic seizures.
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Epileptic seizure
An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.
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Exon
An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.
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Generalized epilepsy with febrile seizures plus
Generalized epilepsy with febrile seizures plus (GEFS+) is a syndromic autosomal dominant disorder where afflicted individuals can exhibit numerous epilepsy phenotypes.
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Homology (biology)
In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.
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Mature messenger RNA
Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation in the course of protein synthesis.
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Membrane potential
The term "membrane potential" may refer to one of three kinds of membrane potential.
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Nav1.1
Nav1.1, also known as the sodium channel, voltage-gated, type I, alpha subunit (SCN1A), is a protein which in humans is encoded by the SCN1A gene.
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Nav1.2
Navα1.2, also known as the sodium channel, voltage-gated, type II, alpha subunit is a protein that in humans is encoded by the SCN2A gene.
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RNA editing
RNA editing is a molecular process through which some cells can make discrete changes to specific nucleotide sequences within an RNA molecule after it has been generated by RNA polymerase.
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SCN8A
Sodium channel, voltage gated, type VIII, alpha subunit also known as SCN8A or Nav1.6 is a membrane protein encoded by the SCN8A gene.
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Sodium
Sodium is a chemical element with symbol Na (from Latin natrium) and atomic number 11.
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Sodium channel
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
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Three prime untranslated region
In molecular genetics, the three prime untranslated region (3'-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon.
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Voltage-gated ion channel
Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in the electrical membrane potential near the channel.
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