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C2 domain

Index C2 domain

A C2 domain is a protein structural domain involved in targeting proteins to cell membranes. [1]

99 relations: BAIAP3, BCR (gene), Beta sheet, Beta-sandwich, CADPS, CADPS2, Calcium, CAPN5, CAPN6, CC2D1A, Cell membrane, CPNE1, CPNE4, CPNE6, CPNE8, DAB2IP, DOC2A, DOC2B, Dysferlin, Enzyme, FAM62A, FAM62B, FER1L3, HECW1, HECW2, Inositol, Intersectin 1, Intersectin 2, ITCH, NEDD4, NEDD4L, OTOF, PCLO, Perforin, Phosphatase, Phosphatidylinositol, Phosphatidylinositol (3,4,5)-trisphosphate, Phosphoinositide 3-kinase, Phosphorylation, PIK3C2A, PIK3C2B, PIK3C2G, PLA2G4A, PLA2G4B, PLCB1, PLCB2, PLCB3, PLCB4, PLCD1, PLCD3, ..., PLCD4, PLCE1, PLCG1, PLCG2, PRKCB1, PRKCE, PRKCG, PRKCH, Protein, Protein domain, Protein tyrosine phosphatase, PTEN (gene), RAB11FIP1, RAB11FIP2, RAB11FIP5, RAS p21 protein activator 1, RASA3, RASA4, RASAL2, RGS3, RIMS1, RIMS2, RPGRIP1, RPGRIP1L, RPH3A, SMURF1, SMURF2, SYNGAP1, SYT1, SYT11, SYT13, SYT14, SYT2, SYT3, SYT4, SYT5, SYT6, SYT7, SYT9, SYTL1, SYTL2, SYTL4, TOLLIP, UNC13A, UNC13B, UNC13D, WWC2, WWP1, WWP2. Expand index (49 more) »

BAIAP3

BAI1-associated protein 3 is a protein that in humans is encoded by the BAIAP3 gene.

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BCR (gene)

The breakpoint cluster region protein (BCR) also known as renal carcinoma antigen NY-REN-26 is a protein that in humans is encoded by the BCR gene.

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Beta sheet

The β-sheet (also β-pleated sheet) is a common motif of regular secondary structure in proteins.

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Beta-sandwich

β-sandwich domains consisting of 80 to 350 amino acids occur commonly in proteins.

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CADPS

Calcium-dependent secretion activator 1 is a protein that in humans is encoded by the CADPS gene.

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CADPS2

Calcium-dependent secretion activator 2 is a protein that in humans is encoded by the CADPS2 gene.

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Calcium

Calcium is a chemical element with symbol Ca and atomic number 20.

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CAPN5

Calpain-5 is a protein that in humans is encoded by the CAPN5 gene.

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CAPN6

Calpain 6 is a protein in humans that is encoded by the CAPN6 gene.

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CC2D1A

Coiled-coil and C2 domain-containing protein 1A is a protein that in humans is encoded by the CC2D1A gene.

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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CPNE1

Copine-1 is a protein that in humans is encoded by the CPNE1 gene.

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CPNE4

Copine-4 is a protein that in humans is encoded by the CPNE4 gene.

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CPNE6

Copine-6 is a protein that in humans is encoded by the CPNE6 gene.

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CPNE8

Copine-8 is a protein that in humans is encoded by the CPNE8 gene.

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DAB2IP

Disabled homolog 2-interacting protein is a protein that in humans is encoded by the DAB2IP gene.

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DOC2A

Double C2-like domain-containing protein alpha is a protein that in humans is encoded by the DOC2A gene.

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DOC2B

Double C2-like domain-containing protein beta is a protein that in humans is encoded by the DOC2B gene.

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Dysferlin

Dysferlin also known as dystrophy-associated fer-1-like protein is a protein that in humans is encoded by the DYSF gene.

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Enzyme

Enzymes are macromolecular biological catalysts.

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FAM62A

Extended synaptotagmin-1 is a protein in humans that is encoded by the ESYT1 gene.

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FAM62B

Extended synaptotagmin-2 is a protein that in humans is encoded by the ESYT2 gene.

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FER1L3

Myoferlin is a protein that in humans is encoded by the MYOF gene.

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HECW1

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 is a protein that in humans is encoded by the HECW1 gene.

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HECW2

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 is a protein that in humans is encoded by the HECW2 gene.

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Inositol

Myo-inositol, or simply inositol, is a carbocyclic sugar that is abundant in brain and other mammalian tissues, mediates cell signal transduction in response to a variety of hormones, neurotransmitters and growth factors and participates in osmoregulation It is a sugar alcohol with half the sweetness of sucrose (table sugar).

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Intersectin 1

Intersectin-1 is a protein that, in humans, is encoded by the ITSN1 gene.

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Intersectin 2

Intersectin-2 is a protein that in humans is encoded by the ITSN2 gene.

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ITCH

ITCH is an ubiquitin-conjugating enzyme.

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NEDD4

E3 ubiquitin-protein ligase NEDD4 also known as neural precursor cell expressed developmentally down-regulated protein 4 (NEDD4) is an enzyme that in humans is encoded by the NEDD4 gene.

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NEDD4L

Neural precursor cell expressed developmentally downregulated gene 4-like (NEDD4L) or NEDD4-2 (NEDD4-2) is an enzyme (ubiquitin ligase) of the NEDD4 family.

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OTOF

Otoferlin is a protein that in humans is encoded by the OTOF gene.

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PCLO

Protein piccolo is a protein that in humans is encoded by the PCLO gene.

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Perforin

Perforin-1 is a protein that in humans is encoded by the PRF1 gene and the Prf1 gene in mice.

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Phosphatase

A phosphatase is an enzyme that uses water to cleave a phosphoric acid monoester into a phosphate ion and an alcohol.

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Phosphatidylinositol

Phosphatidylinositol consists of a family of lipids as illustrated on the right, a class of the phosphatidylglycerides.

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Phosphatidylinositol (3,4,5)-trisphosphate

Phosphatidylinositol (3,4,5)-trisphosphate (PtdIns(3,4,5)P3), abbreviated PIP3, is the product of the class I phosphoinositide 3-kinases (PI 3-kinases) phosphorylation of phosphatidylinositol (4,5)-bisphosphate (PIP2).

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Phosphoinositide 3-kinase

Phosphatidylinositol-4,5-bisphosphate 3-kinase (also called phosphatidylinositide 3-kinases, phosphatidylinositol-3-kinases, PI 3-kinases, PI(3)Ks, PI-3Ks or by the HUGO official stem symbol for the gene family, PI3K(s)) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

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Phosphorylation

In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.

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PIK3C2A

Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide is an enzyme that in humans is encoded by the PIK3C2A gene.

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PIK3C2B

Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide is an enzyme that in humans is encoded by the PIK3C2B gene.

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PIK3C2G

Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide is an enzyme that in humans is encoded by the PIK3C2G gene.

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PLA2G4A

Cytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene.

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PLA2G4B

Phospholipase A2, group IVB (cytosolic), also known as PLA2G4B, is a human gene.

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PLCB1

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 is an enzyme that in humans is encoded by the PLCB1 gene.

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PLCB2

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene.

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PLCB3

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 is an enzyme that in humans is encoded by the PLCB3 gene.

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PLCB4

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 is an enzyme that in humans is encoded by the PLCB4 gene.

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PLCD1

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 is an enzyme that in humans is encoded by the PLCD1 gene.

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PLCD3

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 is an enzyme that in humans is encoded by the PLCD3 gene.

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PLCD4

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4 is an enzyme that in humans is encoded by the PLCD4 gene.

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PLCE1

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 is an enzyme that in humans is encoded by the PLCE1 gene.

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PLCG1

Phospholipase C, gamma 1, also known as PLCG1, is a protein that in humans is encoded by the PLCG1 gene.

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PLCG2

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 is an enzyme that in humans is encoded by the PLCG2 gene.

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PRKCB1

Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene.

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PRKCE

Protein kinase C epsilon type (PKCε) is an enzyme that in humans is encoded by the PRKCE gene.

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PRKCG

Protein kinase C gamma type is an enzyme that in humans is encoded by the PRKCG gene.

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PRKCH

Protein kinase C eta type is an enzyme that in humans is encoded by the PRKCH gene.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein domain

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.

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Protein tyrosine phosphatase

Protein tyrosine phosphatases are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins.

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PTEN (gene)

Phosphatase and tensin homolog (PTEN) is a protein that, in humans, is encoded by the PTEN gene.

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RAB11FIP1

Rab11 family-interacting protein 1 (Rab11-FIP1) also known as Rab-coupling protein is a protein that in humans is encoded by the RAB11FIP1 gene.

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RAB11FIP2

Rab11 family-interacting protein 2 is a protein that in humans is encoded by the RAB11FIP2 gene.

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RAB11FIP5

Rab11 family-interacting protein 5 is a protein that in humans is encoded by the RAB11FIP5 gene.

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RAS p21 protein activator 1

RAS p21 protein activator 1 or RasGAP (Ras GTPase activating protein), also known as RASA1, is a 120-kDa cytosolic human protein that provides two principal activities.

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RASA3

Ras GTPase-activating protein 3 is an enzyme that in humans is encoded by the RASA3 gene.

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RASA4

Ras GTPase-activating protein 4 is an enzyme that in humans is encoded by the RASA4 gene.

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RASAL2

Ras GTPase-activating protein nGAP is an enzyme that in humans is encoded by the RASAL2 gene.

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RGS3

Regulator of G-protein signaling 3 is a protein that in humans is encoded by the RGS3 gene.

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RIMS1

Regulating synaptic membrane exocytosis protein 1 is a protein that in humans is encoded by the RIMS1 gene.

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RIMS2

Regulating synaptic membrane exocytosis protein 2 is a protein that in humans is encoded by the RIMS2 gene.

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RPGRIP1

X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 is an protein in the ciliary transition zone that in humans is encoded by the RPGRIP1 gene.

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RPGRIP1L

RPGRIP1L is a human gene.

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RPH3A

Rabphilin-3A is a protein that in humans is encoded by the RPH3A gene.

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SMURF1

E3 ubiquitin-protein ligase SMURF1 is an enzyme that in humans is encoded by the SMURF1 gene.

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SMURF2

E3 ubiquitin-protein ligase SMURF2 is an enzyme that in humans is encoded by the SMURF2 gene.

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SYNGAP1

Synaptic Ras GTPase-activating protein 1, also known as synaptic Ras-GAP 1 or SYNGAP1, is a protein that in humans is encoded by the SYNGAP1 gene.

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SYT1

Synaptotagmin-1 is a protein that in humans is encoded by the SYT1 gene.

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SYT11

Synaptotagmin-11 is a protein that in humans is encoded by the SYT11 gene.

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SYT13

Synaptotagmin-13 is a protein that in humans is encoded by the SYT13 gene.

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SYT14

Synaptotagmin XIV is a protein that in humans is encoded by the SYT14 gene.

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SYT2

Synaptotagmin-2 is a protein that in humans is encoded by the SYT2 gene.

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SYT3

Synaptotagmin-3 is a protein that in humans is encoded by the SYT3 gene.

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SYT4

Synaptotagmin-4 is a protein that in humans is encoded by the SYT4 gene.

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SYT5

Synaptotagmin-5 is a protein that in humans is encoded by the SYT5 gene.

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SYT6

Synaptotagmin-6 is a protein that in humans is encoded by the SYT6 gene.

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SYT7

Synaptotagmin-7 is a protein that in humans is encoded by the SYT7 gene.

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SYT9

Synaptotagmin-9 is a protein that in humans is encoded by the SYT9 gene.

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SYTL1

Synaptotagmin-like protein 1 is a protein that in humans is encoded by the SYTL1 gene.

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SYTL2

Synaptotagmin-like 2, also known as SYTL2, is a human gene.

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SYTL4

Synaptotagmin-like protein 4 is a protein that in humans is encoded by the SYTL4 gene.

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TOLLIP

Toll interacting protein, also known as TOLLIP, is an inhibitory adaptor protein that in humans is encoded by the TOLLIP gene.

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UNC13A

Unc-13 homolog A (C. elegans) is a protein that in humans is encoded by the UNC13A gene.

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UNC13B

Protein unc-13 homolog B is a protein that in humans is encoded by the UNC13B gene.

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UNC13D

Protein unc-13 homolog D, also known as munc13-4, is a protein that in humans is encoded by the UNC13D gene.

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WWC2

WW and C2 domain containing 2 (WWC2) is a protein that in humans is encoded by the WWC2 gene (4q35.1).

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WWP1

NEDD4-like E3 ubiquitin-protein ligase WWP1 is an enzyme that in humans is encoded by the WWP1 gene.

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WWP2

NEDD4-liثثبقثke E3 ubiquitin-protein ligase WWP2 also known as atrophin-1-interacting protein 2 (AIP2) or WW domain-containing protein 2 (WWP2) is an enzyme that in humans is encoded by the WWP2 gene.

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C2 domains.

References

[1] https://en.wikipedia.org/wiki/C2_domain

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