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CHEK1

Index CHEK1

Checkpoint kinase 1, commonly referred to as Chk1 is an Serine/threonine-specific protein kinase that in humans, is encoded by the CHEK1 gene. [1]

12 relations: Ataxia telangiectasia and Rad3 related, ATM serine/threonine kinase, CHEK2, DNA repair, G2-M DNA damage checkpoint, Gene, Genetic recombination, Meiosis, Oocyte, Serine/threonine-specific protein kinase, Synaptonemal complex, Testicle.

Ataxia telangiectasia and Rad3 related

Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein (ATR) or FRAP-related protein 1 (FRP1) is an enzyme that, in humans, is encoded by the ATR gene.

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ATM serine/threonine kinase

ATM serine/threonine kinase, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks.

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CHEK2

CHEK2 (Checkpoint kinase 2) is a tumor suppressor gene that encodes the protein CHK2, a serine-threonine kinase.

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DNA repair

DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.

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G2-M DNA damage checkpoint

The G2-M DNA damage checkpoint is an important cell cycle checkpoint in eukaryotic organisms ranging from yeast to mammals.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Genetic recombination

Genetic recombination (aka genetic reshuffling) is the production of offspring with combinations of traits that differ from those found in either parent.

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Meiosis

Meiosis (from Greek μείωσις, meiosis, which means lessening) is a specialized type of cell division that reduces the chromosome number by half, creating four haploid cells, each genetically distinct from the parent cell that gave rise to them.

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Oocyte

An oocyte, oöcyte, ovocyte, or rarely ocyte, is a female gametocyte or germ cell involved in reproduction.

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Serine/threonine-specific protein kinase

A serine/threonine protein kinase is a kinase enzyme that phosphorylates the OH group of serine or threonine (which have similar sidechains).

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Synaptonemal complex

The synaptonemal complex (SC) is a protein structure that forms between homologous chromosomes (two pairs of sister chromatids) during meiosis and is thought to mediate chromosome pairing, synapsis, and recombination.

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Testicle

The testicle or testis is the male reproductive gland in all animals, including humans.

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Redirects here:

CHEK1 (gene), CHK-1, Chk1.

References

[1] https://en.wikipedia.org/wiki/CHEK1

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