CcdA/CcdB Type II Toxin-antitoxin system

The CcdA/CcdB Type II Toxin-antitoxin system is one example of the bacterial toxin-antitoxin (TA) systems that encode two proteins, one a potent inhibitor of cell proliferation (toxin) and the other its specific antidote (antitoxin). ^[1]

12 relations: Amino acid, Bacteria, DNA gyrase, Operon, Plasmid, Protein, Protein complex, Repressor, Topoisomerase, Toxicity, Toxin-antitoxin system, Transcription (biology).

Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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DNA gyrase

DNA gyrase, or simply gyrase, is an enzyme within the class of topoisomerase (Type II topoisomerase) that relieves strain while double-stranded DNA is being unwound by helicase.

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Operon

In genetics, an operon is a functioning unit of DNA containing a cluster of genes under the control of a single promoter.

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Plasmid

A plasmid is a small DNA molecule within a cell that is physically separated from a chromosomal DNA and can replicate independently.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein complex

A protein complex or multiprotein complex is a group of two or more associated polypeptide chains.

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Repressor

In molecular genetics, a repressor is a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers.

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Topoisomerase

Topoisomerases are enzymes that participate in the overwinding or underwinding of DNA.

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Toxicity

Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.

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Toxin-antitoxin system

A toxin-antitoxin system is a set of two or more closely linked genes that together encode both a protein 'poison' and a corresponding 'antidote'.

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Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

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References

[1] https://en.wikipedia.org/wiki/CcdA/CcdB_Type_II_Toxin-antitoxin_system

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