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26 relations: Antibody, Antiparallel (biochemistry), B cell, Beta sheet, Cluster of differentiation, Extracellular, Fibronectin, Fibronectin type III domain, Gene, Helminths, Immune response, Immunoglobulin E, Interferon gamma, Interleukin 13, Interleukin 4, Macrophage, Macrophage polarization, Macrophage-activating factor, N-terminus, Protein folding, Protein–protein interaction, SHC1, T cell, T helper cell, Tumor necrosis factor alpha, Type I cytokine receptor.
Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
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Antiparallel (biochemistry)
In biochemistry, two biopolymers are antiparallel if they run parallel to each other but with opposite alignments.
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B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
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Beta sheet
The β-sheet (also β-pleated sheet) is a common motif of regular secondary structure in proteins.
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Cluster of differentiation
The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells.
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Extracellular
In cell biology, molecular biology and related fields, the word extracellular (or sometimes extracellular space) means "outside the cell".
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Fibronectin
Fibronectin is a high-molecular weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins.
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Fibronectin type III domain
The Fibronectin type III domain is an evolutionary conserved protein domain that is widely found in animal proteins.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Helminths
Helminths, also commonly known as parasitic worms, are large multicellular parasites, which can generally be seen with the naked eye when they are mature.
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Immune response
The Immune response is the body's response caused by its immune system being activated by antigens.
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Immunoglobulin E
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals.
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Interferon gamma
Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons.
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Interleukin 13
Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene.
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Interleukin 4
The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells.
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Macrophage
Macrophages (big eaters, from Greek μακρός (makrós).
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Macrophage polarization
Macrophage polarization is a process by which macrophage expresses different functional programs in response to microenvironmental signals.
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Macrophage-activating factor
A macrophage-activating factor (MAF) is a lymphokine or other receptor based signal that primes macrophages towards cytotoxicity to tumors, cytokine secretion, or clearance of pathogens.
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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Protein folding
Protein folding is the physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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SHC1
SHC-transforming protein 1 is a protein that in humans is encoded by the SHC1 gene.
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T cell
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
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T helper cell
The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system.
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Tumor necrosis factor alpha
Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.
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Type I cytokine receptor
Type I cytokine receptors are transmembrane receptors expressed on the surface of cells that recognize and respond to cytokines with four α-helical strands.
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Redirects here:
CD124, Cd124, IL-4 receptor, IL4R, IL4R (gene), IL4RA, Interleukin 4 receptor.
References
[1] https://en.wikipedia.org/wiki/Interleukin-4_receptor
