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Selectin

Index Selectin

The selectins (cluster of differentiation 62 or CD62) are a family of cell adhesion molecules (or CAMs). [1]

32 relations: Blood vessel, Bone marrow, C-type lectin, Cell (biology), Cell adhesion molecule, Circulatory system, Cluster of differentiation, Cytokine, E-selectin, Endothelium, Epidermal growth factor, Glycoprotein, Histamine, Inflammation, Integrin, L-selectin, Lectin, Leukocyte extravasation, Lymphocyte, Moiety (chemistry), Molecule, N-terminus, Osteoblast, Osteoporosis, P-selectin, P-selectin glycoprotein ligand-1, Platelet, Polymer, Stem cell, Sushi domain, Thrombin, Tumor necrosis factor alpha.

Blood vessel

The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.

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Bone marrow

Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones.

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C-type lectin

A C-type lectin (CLEC) is a type of carbohydrate-binding protein domain known as a lectin.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Cell adhesion molecule

Cell adhesion molecules (CAMs) are proteins located on the cell surface involved in binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion.

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Circulatory system

The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.

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Cluster of differentiation

The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells.

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Cytokine

Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.

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E-selectin

E-selectin, also known as CD62 antigen-like family member E (CD62E), endothelial-leukocyte adhesion molecule 1 (ELAM-1), or leukocyte-endothelial cell adhesion molecule 2 (LECAM2), is a cell adhesion molecule expressed only on endothelial cells activated by cytokines.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Epidermal growth factor

Epidermal growth factor (EGF) stimulates cell growth and differentiation by binding to its receptor, EGFR.

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Glycoprotein

Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to amino acid side-chains.

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Histamine

Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Integrin

Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.

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L-selectin

L-selectin, also known as CD62L, is a cell adhesion molecule found on lymphocytes and the preimplantation embryo.

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Lectin

Lectins are carbohydrate-binding proteins, macromolecules that are highly specific for sugar moieties of other molecules.

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Leukocyte extravasation

Leukocyte extravasation, less commonly called diapedesis, is the movement of leukocytes out of the circulatory system and towards the site of tissue damage or infection.

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Lymphocyte

A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.

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Moiety (chemistry)

In organic chemistry, a moiety is a part of a molecule.

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Molecule

A molecule is an electrically neutral group of two or more atoms held together by chemical bonds.

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N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.

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Osteoblast

Osteoblasts (from the Greek combining forms for "bone", ὀστέο-, osteo- and βλαστάνω, blastanō "germinate") are cells with a single nucleus that synthesize bone.

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Osteoporosis

Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone.

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P-selectin

P-selectin is a protein that in humans is encoded by the SELP gene.

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P-selectin glycoprotein ligand-1

Selectin P ligand, also known as SELPLG or CD162 (cluster of differentiation 162), is a human gene.

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Platelet

Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.

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Polymer

A polymer (Greek poly-, "many" + -mer, "part") is a large molecule, or macromolecule, composed of many repeated subunits.

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Stem cell

Stem cells are biological cells that can differentiate into other types of cells and can divide to produce more of the same type of stem cells.

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Sushi domain

Sushi domain is an evolutionarily conserved protein domain.

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Thrombin

Thrombin (fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, an enzyme that, in humans, is encoded by the F2 gene.

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Tumor necrosis factor alpha

Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.

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CD62, Cd62, Selectins.

References

[1] https://en.wikipedia.org/wiki/Selectin

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