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ConsensusPathDB

Index ConsensusPathDB

The ConsensusPathDB is a molecular functional interaction database, integrating information on protein interactions, genetic interactions signaling, metabolism, gene regulation, and drug-target interactions in humans. [1]

24 relations: BioGRID, BioPAX, Cell signaling, Database, Database of Interacting Proteins, Epistasis, Human Protein Reference Database, Hypergeometric distribution, Interactome, KEGG, Max Planck Society, Metabolic pathway, Metabolism, Metabolite, Netpath, P-value, Physical body, Protein, Reactome, Regulation of gene expression, SBML, UniProt, User interface, WikiPathways.

BioGRID

The Biological General Repository for Interaction Datasets (BioGRID) is a curated biological database of protein-protein interactions, genetic interactions, chemical interactions, and post-translational modifications created in 2003 (originally referred to as simply the General Repository for Interaction Datasets (GRID) by Mike Tyers, Bobby-Joe Breitkreutz, and Chris Stark at the Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital. It strives to provide a comprehensive curated resource for all major model organism species while attempting to remove redundancy to create a single mapping of data. Users of The BioGRID can search for their protein or publication of interest and retrieve annotation, as well as curated data as reported, by the primary literature and compiled by in house large-scale curation efforts. The BioGRID is hosted in Toronto, Ontario, Canada and Dallas, Texas, United States and is partnered with the Saccharomyces Genome Database. The BioGRID is funded by the BBSRC, NIH, and CIHR. BioGRID is a member of the (IMEx).

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BioPAX

BioPAX (Biological Pathway Exchange) is a RDF/OWL-based standard language to represent biological pathways at the molecular and cellular level.

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Cell signaling

Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions.

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Database

A database is an organized collection of data, stored and accessed electronically.

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Database of Interacting Proteins

The Database of Interacting Proteins (DIP) is a biological database which catalogs experimentally determined interactions between proteins.

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Epistasis

Epistasis is the phenomenon where the effect of one gene (locus) is dependent on the presence of one or more 'modifier genes', i.e. the genetic background.

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Human Protein Reference Database

The Human Protein Reference Database (HPRD) is a protein database accessible through the Internet.

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Hypergeometric distribution

In probability theory and statistics, the hypergeometric distribution is a discrete probability distribution that describes the probability of k successes (random draws for which the object drawn has a specified feature) in n draws, without replacement, from a finite population of size N that contains exactly K objects with that feature, wherein each draw is either a success or a failure.

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Interactome

In molecular biology, an interactome is the whole set of molecular interactions in a particular cell.

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KEGG

KEGG (Kyoto Encyclopedia of Genes and Genomes) is a collection of databases dealing with genomes, biological pathways, diseases, drugs, and chemical substances.

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Max Planck Society

The Max Planck Society for the Advancement of Science (Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V.; abbreviated MPG) is a formally independent non-governmental and non-profit association of German research institutes founded in 1911 as the Kaiser Wilhelm Society and renamed the Max Planck Society in 1948 in honor of its former president, theoretical physicist Max Planck.

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Metabolic pathway

In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell.

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Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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Netpath

NetPath is a manually curated resource of human signal transduction pathways.

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P-value

In statistical hypothesis testing, the p-value or probability value or asymptotic significance is the probability for a given statistical model that, when the null hypothesis is true, the statistical summary (such as the sample mean difference between two compared groups) would be the same as or of greater magnitude than the actual observed results.

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Physical body

In physics, a physical body or physical object (or simply a body or object) is an identifiable collection of matter, which may be constrained by an identifiable boundary, and may move as a unit by translation or rotation, in 3-dimensional space.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Reactome

Reactome is a free online database of biological pathways.

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Regulation of gene expression

Regulation of gene expression includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA), and is informally termed gene regulation.

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SBML

The Systems Biology Markup Language (SBML) is a representation format, based on XML, for communicating and storing computational models of biological processes.

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UniProt

UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects.

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User interface

The user interface (UI), in the industrial design field of human–computer interaction, is the space where interactions between humans and machines occur.

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WikiPathways

WikiPathways is a community resource for contributing and maintaining content dedicated to biological pathways.

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Redirects here:

Cpdb.

References

[1] https://en.wikipedia.org/wiki/ConsensusPathDB

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