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Cyclin

Index Cyclin

Cyclin is a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes. [1]

59 relations: Active site, African clawed frog, C-terminus, CCNC (gene), CCNF, CCNG1, CCNG2, CCNI (gene), CCNL1, CCNL2, Cell cycle, Centrosome, Chromatin structure remodeling (RSC) complex, Cyclin A, Cyclin A1, Cyclin A2, Cyclin B, Cyclin B1, Cyclin B2, Cyclin D, Cyclin D1, Cyclin D2, Cyclin D3, Cyclin E, Cyclin E1, Cyclin E2, Cyclin H, Cyclin K, Cyclin O, Cyclin T1, Cyclin T2, Cyclin-dependent kinase, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, Cyclin-dependent kinase 4, Cyclin-dependent kinase 6, DNA replication, Drosophila melanogaster, Enzyme, Flow cytometry, Homo sapiens, Jim Al-Khalili, Kinase, Leland H. Hartwell, Maturation promoting factor, Metaphase, Microtubule, Mitosis, N-terminus, Nobel Prize in Physiology or Medicine, ..., Paul Nurse, Phosphorylation, Protein domain, Protein family, Protein fold class, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Spindle pole body, Tim Hunt. Expand index (9 more) »

Active site

In biology, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction.

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African clawed frog

The African clawed frog (Xenopus laevis, also known as the xenopus, African clawed toad, African claw-toed frog or the platanna) is a species of African aquatic frog of the family Pipidae.

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C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

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CCNC (gene)

Cyclin-C is a protein that in humans is encoded by the CCNC gene.

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CCNF

G2/mitotic-specific cyclin-F is a protein that in humans is encoded by the CCNF gene.

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CCNG1

Cyclin-G1 is a protein that in humans is encoded by the CCNG1 gene.

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CCNG2

Cyclin-G2 is a protein that in humans is encoded by the CCNG2 gene.

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CCNI (gene)

Cyclin-I is a protein that in humans is encoded by the CCNI gene.

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CCNL1

Cyclin-L1 is a protein that in humans is encoded by the CCNL1 gene.

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CCNL2

Cyclin-L2 is a protein that in humans is encoded by the CCNL2 gene.

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Cell cycle

The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.

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Centrosome

In cell biology, the centrosome (Latin centrum 'center' + Greek sōma 'body') is an organelle that serves as the main microtubule organizing center (MTOC) of the animal cell as well as a regulator of cell-cycle progression.

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Chromatin structure remodeling (RSC) complex

RSC (Remodelling the Structure of Chromatin) is a member of the ATP-dependent chromatin remodeller family (other members being the SWI/SNF, INO80, ISW1 and CHD complexes).

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Cyclin A

Cyclin A is a member of the cyclin family, a group of proteins that function in regulating progression through the cell cycle.

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Cyclin A1

Cyclin-A1 is a protein that in humans is encoded by the CCNA1 gene.

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Cyclin A2

Cyclin-A2 is a protein that in humans is encoded by the CCNA2 gene.

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Cyclin B

Cyclin B is a member of the cyclin family.

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Cyclin B1

G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene.

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Cyclin B2

G2/mitotic-specific cyclin-B2 is a protein that in humans is encoded by the CCNB2 gene.

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Cyclin D

Cyclin D is a member of the cyclin protein family that is involved in regulating cell cycle progression.

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Cyclin D1

Cyclin D1 is a protein that in humans is encoded by the CCND1 gene.

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Cyclin D2

G1/S-specific cyclin-D2 is a protein that in humans is encoded by the CCND2 gene.

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Cyclin D3

G1/S-specific cyclin-D3 is a protein that in humans is encoded by the CCND3 gene.

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Cyclin E

Cyclin E is a member of the cyclin family.

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Cyclin E1

G1/S-specific cyclin-E1 is a protein that in humans is encoded by the CCNE1 gene.

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Cyclin E2

Cyclin E2 is a protein that in humans is encoded by the CCNE2 gene.

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Cyclin H

Cyclin-H is a protein that in humans is encoded by the CCNH gene.

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Cyclin K

Cyclin-K is a protein that in humans is encoded by the CCNK gene.

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Cyclin O

Cyclin-O is a protein that in humans is encoded by the CCNO gene.

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Cyclin T1

Cyclin-T1 is a protein that in humans is encoded by the CCNT1 gene.

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Cyclin T2

Cyclin-T2 is a protein that in humans is encoded by the CCNT2 gene.

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Cyclin-dependent kinase

Gap phase 2. The duration of mitosis in relation to the other phases has been exaggerated in this diagram Cyclin-dependent kinases (CDKs) are a family of sugar kinases first discovered for their role in regulating the cell cycle.

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Cyclin-dependent kinase 1

Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine kinase, and is a key player in cell cycle regulation.

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Cyclin-dependent kinase 2

Cyclin-dependent kinase 2, also known as cell division protein kinase 2, is an enzyme that in humans is encoded by the CDK2 gene.

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Cyclin-dependent kinase 4

Cyclin-dependent kinase 4 also known as cell division protein kinase 4 is an enzyme that in humans is encoded by the CDK4 gene.

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Cyclin-dependent kinase 6

Cell division protein kinase 6 (CDK6) is an enzyme encoded by the CDK6 gene.

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DNA replication

In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.

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Drosophila melanogaster

Drosophila melanogaster is a species of fly (the taxonomic order Diptera) in the family Drosophilidae.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Flow cytometry

In biotechnology, flow cytometry is a laser- or impedance-based, biophysical technology employed in cell counting, cell sorting, biomarker detection and protein engineering, by suspending cells in a stream of fluid and passing them through an electronic detection apparatus.

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Homo sapiens

Homo sapiens is the systematic name used in taxonomy (also known as binomial nomenclature) for the only extant human species.

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Jim Al-Khalili

Jameel Sadik Al-Khalili (born 20 September 1962) is a British theoretical physicist, author and broadcaster.

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Kinase

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates.

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Leland H. Hartwell

Leland Harrison (Lee) Hartwell (born October 30, 1939, in Los Angeles, California) is former president and director of the Fred Hutchinson Cancer Research Center in Seattle, Washington.

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Maturation promoting factor

Maturation-promoting factor (abbreviated MPF, also called mitosis-promoting factor or M-Phase-promoting factor) is the cyclin-Cdk complex that was discovered first in frog eggs.

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Metaphase

Metaphase (from the Greek μετά, "adjacent" and φάσις, "stage") is a stage of mitosis in the eukaryotic cell cycle in which chromosomes are at their second-most condensed and coiled stage (they are at their most condensed in anaphase).

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Microtubule

Microtubules are tubular polymers of tubulin that form part of the cytoskeleton that provides the cytoplasm of eukaryotic cells and some bacteria with structure and shape.

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Mitosis

In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.

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N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.

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Nobel Prize in Physiology or Medicine

The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin), administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the fields of life sciences and medicine.

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Paul Nurse

Sir Paul Maxime Nurse (born 25 January 1949), is an English geneticist, former President of the Royal Society and Chief Executive and Director of the Francis Crick Institute.

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Phosphorylation

In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.

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Protein domain

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.

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Protein family

A protein family is a group of evolutionarily-related proteins.

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Protein fold class

Protein classes are broad categories of protein topologies.

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Saccharomyces cerevisiae

Saccharomyces cerevisiae is a species of yeast.

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Schizosaccharomyces pombe

Schizosaccharomyces pombe, also called "fission yeast", is a species of yeast used in traditional brewing and as a model organism in molecular and cell biology.

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Spindle pole body

The spindle pole body (SPB) is the microtubule organizing center in yeast cells, functionally equivalent to the centrosome.

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Tim Hunt

Sir Richard Timothy Hunt, (born 19 February 1943) is a British biochemist and molecular physiologist.

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Redirects here:

Cyclin F, Cyclin d1, Cyclins, Cyklin, Mitotic cyclin.

References

[1] https://en.wikipedia.org/wiki/Cyclin

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