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62 relations: Acute respiratory distress syndrome, Adverse effect, Alemtuzumab, Antihistamine, Antihypotensive agent, Avian influenza, Azotemia, B cell, Biopharmaceutical, CD19, CD20, CD3 (immunology), CD52, Chimeric antigen receptor, Clinical Journal of Oncology Nursing, Clinical trial, Common Terminology Criteria for Adverse Events, Complement factor I, Corticosteroid, Cytokine, D-dimer, Dendritic cell, Drug development, Drug discovery, Ebola virus disease, Elevated transaminases, Graft-versus-host disease, Hong Kong, Immune system, In vitro, Influenza A virus subtype H5N1, Interleukin 6, Investigational New Drug, Macrophage, Medical literature, Monoclonal antibody, Monocyte, Multiple sclerosis, Muromonab-CD3, Natural killer cell, Nonsteroidal anti-inflammatory drug, Northwick Park Hospital, Organ transplantation, Orthohantavirus, Oxygen therapy, Pancreatitis, PAREXEL, Pathogen, Rituximab, Sepsis, ..., Severe acute respiratory syndrome, Smallpox, Spanish flu, Systemic inflammatory response syndrome, T cell, The Lancet, Theralizumab, Therapy, Tisagenlecleucel, Tocilizumab, Tumor lysis syndrome, White blood cell. Expand index (12 more) »
Acute respiratory distress syndrome
Acute respiratory distress syndrome (ARDS) is a medical condition occurring in critically ill or critically wounded patients characterized by widespread inflammation in the lungs.
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Adverse effect
In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery.
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Alemtuzumab
Alemtuzumab is a drug used in the treatment of chronic lymphocytic leukemia (CLL), cutaneous T-cell lymphoma (CTCL) and T-cell lymphoma under the trade names Campath, MabCampath and Campath-1H, and in the treatment of multiple sclerosis as Lemtrada.
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Antihistamine
Antihistamines are drugs which treat allergic rhinitis and other allergies.
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Antihypotensive agent
An antihypotensive agent, also known as a vasopressor agent or pressor, is any medication that tends to raise reduced blood pressure.
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Avian influenza
Avian influenza—known informally as avian flu or bird flu is a variety of influenza caused by viruses adapted to birds.
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Azotemia
Azotemia (azot, "nitrogen" + -emia, "blood condition") is a medical condition characterized by abnormally high levels of nitrogen-containing compounds (such as urea, creatinine, various body waste compounds, and other nitrogen-rich compounds) in the blood.
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B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
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Biopharmaceutical
A biopharmaceutical, also known as a biologic(al) medical product, biological, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources.
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CD19
B-lymphocyte antigen CD19, also known as CD19 molecule ('''C'''luster of '''D'''ifferentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12 and CVID3 is a transmembrane protein that in humans is encoded by the gene CD19.
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CD20
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity.
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CD3 (immunology)
In immunology, the CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8+ naive T cells) and also T helper cells (CD4+ naive T cells).
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CD52
CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.
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Chimeric antigen receptor
Chimeric antigen receptors (CARs, also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors) are engineered receptors that combine a new specificity with an immune cell to target cancer cells.
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Clinical Journal of Oncology Nursing
The Clinical Journal of Oncology Nursing is a bimonthly peer-reviewed nursing journal covering oncology nursing.
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Clinical trial
Clinical trials are experiments or observations done in clinical research.
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Common Terminology Criteria for Adverse Events
The Common Terminology Criteria for Adverse Events (CTCAE), formerly called the Common Toxicity Criteria (CTC or NCI-CTC), are a set of criteria for the standardized classification of adverse effects of drugs used in cancer therapy.
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Complement factor I
Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene.
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Corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.
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Cytokine
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
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D-dimer
D-dimer (or D dimer) is a fibrin degradation product (or FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis.
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Dendritic cell
Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.
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Drug development
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.
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Drug discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
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Ebola virus disease
Ebola virus disease (EVD), also known as Ebola hemorrhagic fever (EHF) or simply Ebola, is a viral hemorrhagic fever of humans and other primates caused by ebolaviruses.
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Elevated transaminases
In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver damage.
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Graft-versus-host disease
Graft-versus-host disease (GvHD) is a medical complication following the receipt of transplanted tissue from a genetically different person.
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Hong Kong
Hong Kong (Chinese: 香港), officially the Hong Kong Special Administrative Region of the People's Republic of China, is an autonomous territory of China on the eastern side of the Pearl River estuary in East Asia.
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Immune system
The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.
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In vitro
In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
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Influenza A virus subtype H5N1
Influenza A virus subtype H5N1, also known as A(H5N1) or simply H5N1, is a subtype of the influenza A virus which can cause illness in humans and many other animal species.
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Interleukin 6
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine.
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Investigational New Drug
The United States Food and Drug Administration's Investigational New Drug (IND) program is the means by which a pharmaceutical company obtains permission to ship an experimental drug across state lines (usually to clinical investigators) before a marketing application for the drug has been approved.
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Macrophage
Macrophages (big eaters, from Greek μακρός (makrós).
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Medical literature
Medical literature is the scientific literature of medicine: articles in journals and texts in books devoted to the field of medicine.
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Monoclonal antibody
Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.
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Monocyte
Monocytes are a type of leukocyte, or white blood cell.
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Multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
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Muromonab-CD3
Muromonab-CD3 (trade name Orthoclone OKT3, marketed by Janssen-Cilag) is an immunosuppressant drug given to reduce acute rejection in patients with organ transplants.
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Natural killer cell
Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.
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Nonsteroidal anti-inflammatory drug
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a drug class that reduce pain, decrease fever, prevent blood clots and, in higher doses, decrease inflammation.
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Northwick Park Hospital
Northwick Park Hospital (NPH) is a hospital located in the Northwick Park district of the London Borough of Brent in northwest London, England, adjacent to the borough border with the London Borough of Harrow and serving both boroughs.
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Organ transplantation
Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ.
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Orthohantavirus
Orthohantaviruses (or hantaviruses) are single-stranded, enveloped, negative-sense RNA viruses in the Hantaviridae family of the order Bunyavirales, which normally infect rodents where they do not cause disease.
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Oxygen therapy
Oxygen therapy, also known as supplemental oxygen, is the use of oxygen as a medical treatment.
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Pancreatitis
Pancreatitis is inflammation of the pancreas.
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PAREXEL
PAREXEL International is a global provider of biopharmaceutical services.
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Pathogen
In biology, a pathogen (πάθος pathos "suffering, passion" and -γενής -genēs "producer of") or a '''germ''' in the oldest and broadest sense is anything that can produce disease; the term came into use in the 1880s.
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Rituximab
Rituximab, sold under the brand name Rituxan among others, is a medication used to treat certain autoimmune diseases and types of cancer.
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Sepsis
Sepsis is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs.
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Severe acute respiratory syndrome
Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the SARS coronavirus (SARS-CoV).
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Smallpox
Smallpox was an infectious disease caused by one of two virus variants, Variola major and Variola minor.
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Spanish flu
The Spanish flu (January 1918 – December 1920), also known as the 1918 flu pandemic, was an unusually deadly influenza pandemic, the first of the two pandemics involving H1N1 influenza virus.
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Systemic inflammatory response syndrome
Systemic inflammatory response syndrome (SIRS) is an inflammatory state affecting the whole body.
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T cell
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
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The Lancet
The Lancet is a weekly peer-reviewed general medical journal.
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Theralizumab
Theralizumab (also known as TGN1412, CD28-SuperMAB, and TAB08) is an immunomodulatory drug developed by Professor Thomas Hünig of the University of Würzburg.
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Therapy
Therapy (often abbreviated tx, Tx, or Tx) is the attempted remediation of a health problem, usually following a diagnosis.
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Tisagenlecleucel
Tisagenlecleucel, marketed as Kymriah, is a treatment for B-cell acute lymphoblastic leukemia which uses the body's own T cells to fight cancer (adoptive cell transfer).
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Tocilizumab
Tocilizumab, also known as atlizumab, is an immunosuppressive drug, mainly for the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children.
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Tumor lysis syndrome
Tumor lysis syndrome (TLS) is a group of metabolic abnormalities that can occur as a complication during the treatment of cancer, where large amounts of tumor cells are killed off (lysed) at the same time by the treatment, releasing their contents into the bloodstream.
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White blood cell
White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
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Redirects here:
Cytokine Storm, Cytokine cascade, Cytokine shock, Cytokine storm, Hypercytokinemia, Infusion reaction.
References
[1] https://en.wikipedia.org/wiki/Cytokine_release_syndrome
