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118 relations: Abdominal pain, American Diabetes Association, Artificial pancreas, Autoantibody, Autoimmune disease, Autoimmunity, B cell, Beta cell, Blood sugar level, Blurred vision, Bolus (medicine), Breastfeeding, C-peptide, Cardiovascular disease, CD20, CD3 (immunology), Cerebral edema, Chemotherapy, Chronic kidney disease, Ciclosporin, Coeliac disease, Coxsackie B4 virus, Cytomegalovirus, Diabetes Australia, Diabetes Canada, Diabetes mellitus, Diabetes mellitus type 1, Diabetes mellitus type 2, Diabetes UK, Diabetic diet, Diabetic foot ulcer, Diabetic ketoacidosis, Diabetic neuropathy, Diabetic retinopathy, DNA vaccination, East Asia, Endocrinology, Enterovirus, Epstein–Barr virus, Fatigue, Gliadin, Glucagon rescue, Glucose, Glucose tolerance test, Glutamate decarboxylase, Gluten, Gluten-free diet, Glycated hemoglobin, Heritability, Histocompatibility, ..., HLA-DQB1, Hyperglycemia, Hyperosmolar hyperglycemic state, Hypoglycemia, Immune tolerance, Immunofluorescence, Immunosuppression, Immunosuppressive drug, Innate immune system, Insulin, Insulin (medication), Insulin pump, JDRF, Ketoacidosis, Kidney, Kidney disease, Kuwait, Large for gestational age, Latent autoimmune diabetes of adults, Latin America, Low-carbohydrate diet, Medical Research Council (United Kingdom), Metastasis, MHC class II, Model organism, Mumps, Mycosis, National Institute for Health Research, National Institutes of Health, Nephrotoxicity, Nicotinamide, Oral contraceptive pill, Otelixizumab, Pancreas, Pancreatic islets, Pancreatitis, Peptide, Peripheral neuropathy, Phosphatase, Polycystic ovary syndrome, Polydipsia, Polygene, Polyphagia, Polyuria, Proinsulin, Pyrinuron, Radiobinding assay, Regulatory T cell, Retinopathy, Rituximab, Rotavirus, Rubella, Scandinavia, Sexual dysfunction, Streptozotocin, Stroke, Subcutaneous injection, T helper cell, Teplizumab, The Environmental Determinants of Diabetes in the Young, Twin, Unified atomic mass unit, United States Environmental Protection Agency, Urinary tract infection, Vitamin D, World Health Organization, Xeroderma, Xerostomia. Expand index (68 more) »
Abdominal pain
Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues.
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American Diabetes Association
The American Diabetes Association (ADA) is a United States-based nonprofit that seeks to educate the public about diabetes and to help those affected by it by funding research to manage, cure and prevent diabetes (including type 1 diabetes, type 2 diabetes, gestational diabetes, and pre-diabetes).
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Artificial pancreas
The artificial pancreas is a technology in development to help people with diabetes automatically control their blood glucose level by providing the substitute endocrine functionality of a healthy pancreas.
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Autoantibody
An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins.
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Autoimmune disease
An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.
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Autoimmunity
Autoimmunity is the system of immune responses of an organism against its own healthy cells and tissues.
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B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
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Beta cell
Beta cells (β cells) are a type of cell found in the pancreatic islets of the pancreas.
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Blood sugar level
The blood sugar level, blood sugar concentration, or blood glucose level is the amount of glucose present in the blood of humans and other animals.
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Blurred vision
Blurred vision is an ocular symptom.
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Bolus (medicine)
In medicine, a bolus (from Latin bolus, ball) is the administration of a discrete amount of medication, drug, or other compound within a specific time, generally within 1 - 30 minutes, in order to raise its concentration in blood to an effective level.
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Breastfeeding
Breastfeeding, also known as nursing, is the feeding of babies and young children with milk from a woman's breast.
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C-peptide
The connecting peptide, or C-peptide, is a short 31-amino-acid polypeptide that connects insulin's A-chain to its B-chain in the proinsulin molecule.
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Cardiovascular disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels.
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CD20
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity.
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CD3 (immunology)
In immunology, the CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8+ naive T cells) and also T helper cells (CD4+ naive T cells).
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Cerebral edema
Cerebral edema is excess accumulation of fluid in the intracellular or extracellular spaces of the brain.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Chronic kidney disease
Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney function over a period of months or years.
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Ciclosporin
Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product.
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Coeliac disease
Coeliac disease, also spelled celiac disease, is a long-term autoimmune disorder that primarily affects the small intestine.
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Coxsackie B4 virus
Coxsackie B4 Virus are enteroviruses that belong to the Picornaviridae family.
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Cytomegalovirus
Cytomegalovirus (CMV) (from the Greek cyto-, "cell", and megalo-, "large") is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Betaherpesvirinae.
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Diabetes Australia
Diabetes Australia is the third oldest diabetes association in the world, after the United Kingdom and Portugal.
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Diabetes Canada
Diabetes Canada (known from 1953 to 2017 as the Canadian Diabetes Association or CDA) is a registered national charity whose mission includes serving the 11 million Canadians living with diabetes or prediabetes.
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Diabetes mellitus
Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.
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Diabetes mellitus type 1
Diabetes mellitus type 1, also known as type 1 diabetes, is a form of diabetes mellitus in which not enough insulin is produced.
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Diabetes mellitus type 2
Diabetes mellitus type 2 (also known as type 2 diabetes) is a long-term metabolic disorder that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
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Diabetes UK
Diabetes UK is a British-based patient, healthcare professional and research charity that describes itself as the "leading UK charity that cares for, connects with and campaigns on behalf of all people affected by and at risk of diabetes." The charity campaigns for improvements in the care and treatment of people with diabetes.
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Diabetic diet
A diabetic diet is a diet that is used by people with diabetes mellitus or high blood glucose to minimize symptoms and dangerous consequences of the disease.
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Diabetic foot ulcer
Diabetic foot ulcer is a major complication of diabetes mellitus, and probably the major component of the diabetic foot.
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Diabetic ketoacidosis
Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus.
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Diabetic neuropathy
Diabetic neuropathies are nerve damaging disorders associated with diabetes mellitus.
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Diabetic retinopathy
Diabetic retinopathy, also known as diabetic eye disease, is a medical condition in which damage occurs to the retina due to diabetes mellitus.
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DNA vaccination
DNA vaccination is a technique for protecting against disease by injection with genetically engineered DNA so cells directly produce an antigen, producing a protective immunological response.
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East Asia
East Asia is the eastern subregion of the Asian continent, which can be defined in either geographical or ethno-cultural "The East Asian cultural sphere evolves when Japan, Korea, and what is today Vietnam all share adapted elements of Chinese civilization of this period (that of the Tang dynasty), in particular Buddhism, Confucian social and political values, and literary Chinese and its writing system." terms.
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Endocrinology
Endocrinology (from endocrine + -ology) is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones.
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Enterovirus
Enteroviruses are a genus of positive-sense single-stranded RNA viruses associated with several human and mammalian diseases.
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Epstein–Barr virus
The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known human herpesvirus types in the herpes family, and is one of the most common viruses in humans.
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Fatigue
Fatigue is a subjective feeling of tiredness that has a gradual onset.
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Gliadin
Gliadin (a type of prolamin) is a class of proteins present in wheat and several other cereals within the grass genus Triticum.
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Glucagon rescue
Glucagon rescue is the emergency injection of glucagon in case of severe diabetic hypoglycemia.
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Glucose
Glucose is a simple sugar with the molecular formula C6H12O6.
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Glucose tolerance test
The glucose tolerance test is a medical test in which glucose is given and blood samples taken afterward to determine how quickly it is cleared from the blood.
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Glutamate decarboxylase
Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2.
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Gluten
Gluten (from Latin gluten, "glue") is a composite of storage proteins termed prolamins and glutelins and stored together with starch in the endosperm (which nourishes the embryonic plant during germination) of various cereal (grass) grains.
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Gluten-free diet
A gluten-free diet (GFD) is a diet that strictly excludes gluten, a mixture of proteins found in wheat and related grains, including barley, rye, oat, and all their species and hybrids (such as spelt, kamut, and triticale).
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Glycated hemoglobin
Glycated hemoglobin (hemoglobin A1c, HbA1c, A1C, or Hb1c; sometimes also referred to as being Hb1c or HGBA1C) is a form of hemoglobin that is measured primarily to identify the three-month average plasma glucose concentration.
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Heritability
Heritability is a statistic used in the fields of breeding and genetics that estimates the degree of variation in a phenotypic trait in a population that is due to genetic variation between individuals in that population.
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Histocompatibility
Histocompatibility, or tissue compatibility, is the property of having the same, or sufficiently similar, alleles of a set of genes called human leukocyte antigens (HLA), the human version of the major histocompatibility complex (MHC).
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HLA-DQB1
Major histocompatibility complex, class II, DQ beta 1, also known as HLA-DQB1, is a human gene and also denotes the genetic locus that contains this gene.
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Hyperglycemia
Hyperglycemia, or high blood sugar (also spelled hyperglycaemia or hyperglycæmia) is a condition in which an excessive amount of glucose circulates in the blood plasma.
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Hyperosmolar hyperglycemic state
Hyperosmolar hyperglycemic state (HHS) is a complication of diabetes mellitus in which high blood sugar results in high osmolarity without significant ketoacidosis.
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Hypoglycemia
Hypoglycemia, also known as low blood sugar, is when blood sugar decreases to below normal levels.
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Immune tolerance
Immune tolerance, or immunological tolerance, or immunotolerance, is a state of unresponsiveness of the immune system to substances or tissue that have the capacity to elicit an immune response in given organism.It is induced by prior exposure to that specific antigen.
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Immunofluorescence
Immunofluorescence is a technique used for light microscopy with a fluorescence microscope and is used primarily on microbiological samples.
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Immunosuppression
Immunosuppression is a reduction of the activation or efficacy of the immune system.
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Immunosuppressive drug
Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system.
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Innate immune system
The innate immune system, also known as the non-specific immune system or in-born immunity system, is an important subsystem of the overall immune system that comprises the cells and mechanisms involved in the defense of the host from infection by other organisms.
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Insulin
Insulin (from Latin insula, island) is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body.
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Insulin (medication)
Insulin is a protein hormone that is used as a medication to treat high blood glucose.
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Insulin pump
An insulin pump is a medical device used for the administration of insulin in the treatment of diabetes mellitus, also known as continuous subcutaneous insulin therapy.
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JDRF
JDRF is a nonprofit 501(c)(3) organization that funds type 1 diabetes (T1D) research and advocates for regulation favorable to medical research and that makes it easier to market new medical devices.
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Ketoacidosis
Ketoacidosis is a metabolic state associated with high concentrations of ketone bodies, formed by the breakdown of fatty acids and the deamination of amino acids.
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Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
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Kidney disease
Kidney disease, or renal disease, also known as nephropathy, is damage to or disease of a kidney.
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Kuwait
Kuwait (الكويت, or), officially the State of Kuwait (دولة الكويت), is a country in Western Asia.
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Large for gestational age
Large for gestational age (LGA) is an indication of high prenatal growth rate.
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Latent autoimmune diabetes of adults
Latent autoimmune diabetes of adults (LADA) is a form of diabetes mellitus type 1 that occurs in adulthood, often with a slower course of onset than type 1 diabetes diagnosed in juveniles.
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Latin America
Latin America is a group of countries and dependencies in the Western Hemisphere where Spanish, French and Portuguese are spoken; it is broader than the terms Ibero-America or Hispanic America.
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Low-carbohydrate diet
Low-carbohydrate diets or low-carb diets are dietary programs that restrict carbohydrate consumption.
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Medical Research Council (United Kingdom)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom.
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
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MHC class II
MHC class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells.
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Model organism
A model organism is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the organism model will provide insight into the workings of other organisms.
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Mumps
Mumps is a viral disease caused by the mumps virus.
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Mycosis
Mycosis is a fungal infection of animals, including humans.
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National Institute for Health Research
The National Institute for Health Research (NIHR) is the largest national clinical research funder in Europe with a budget of over £1 billion (approximately USD 1.3 billion) in 2015-16.
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National Institutes of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.
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Nephrotoxicity
Nephrotoxicity is toxicity in the kidneys.
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Nicotinamide
Nicotinamide (NAA), also known as niacinamide, is a form of vitamin B3 found in food and used as a dietary supplement and medication.
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Oral contraceptive pill
Oral contraceptives, abbreviated OCPs, also known as birth control pills, are medications taken by mouth for the purpose of birth control.
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Otelixizumab
Otelixizumab, also known as TRX4, is a monoclonal antibody, which is being developed for the treatment of type 1 diabetes and other autoimmune diseases.
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Pancreas
The pancreas is a glandular organ in the digestive system and endocrine system of vertebrates.
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Pancreatic islets
The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans.
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Pancreatitis
Pancreatitis is inflammation of the pancreas.
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Peptide
Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.
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Peripheral neuropathy
Peripheral neuropathy (PN) is damage to or disease affecting nerves, which may impair sensation, movement, gland or organ function, or other aspects of health, depending on the type of nerve affected.
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Phosphatase
A phosphatase is an enzyme that uses water to cleave a phosphoric acid monoester into a phosphate ion and an alcohol.
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Polycystic ovary syndrome
Polycystic ovary syndrome (PCOS) is a set of symptoms due to elevated androgens (male hormones) in females.
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Polydipsia
Polydipsia is excessive thirst or excess drinking.
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Polygene
A "polygene” or "multiple gene inheritance" is a member of a group of non-epistatic genes that interact additively to influence a phenotypic trait.
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Polyphagia
Polyphagia or hyperphagia is excessive hunger or increased appetite.
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Polyuria
Polyuria is excessive or an abnormally large production or passage of urine (greater than 2.5 or 3 L over 24 hours in adults).
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Proinsulin
Proinsulin is the prohormone precursor to insulin made in the beta cells of the islets of Langerhans, specialized regions of the pancreas.
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Pyrinuron
Pyrinuron (Pyriminil, Vacor) is a chemical compound formerly used as a rodenticide.
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Radiobinding assay
A radiobinding assay is a method of detecting and quantifying antibodies targeted towards a specific antigen.
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Regulatory T cell
The regulatory T cells (Tregs), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease.
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Retinopathy
Retinopathy is any damage to the retina of the eyes, which may cause vision impairment.
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Rituximab
Rituximab, sold under the brand name Rituxan among others, is a medication used to treat certain autoimmune diseases and types of cancer.
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Rotavirus
Rotavirus is the most common cause of diarrhoeal disease among infants and young children.
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Rubella
Rubella, also known as German measles or three-day measles, is an infection caused by the rubella virus.
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Scandinavia
Scandinavia is a region in Northern Europe, with strong historical, cultural and linguistic ties.
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Sexual dysfunction
Sexual dysfunction (or sexual malfunction or sexual disorder) is difficulty experienced by an individual or a couple during any stage of a normal sexual activity, including physical pleasure, desire, preference, arousal or orgasm.
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Streptozotocin
Streptozotocin or streptozocin (INN, USP) (STZ) is a naturally occurring alkylating antineoplastic agent that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals.
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Stroke
A stroke is a medical condition in which poor blood flow to the brain results in cell death.
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Subcutaneous injection
A subcutaneous injection is administered as a bolus into the subcutis, the layer of skin directly below the dermis and epidermis, collectively referred to as the cutis.
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T helper cell
The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system.
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Teplizumab
Teplizumab (also known as MGA031 and hOKT3γ1(Ala-Ala)) is a humanized monoclonal antibody that failed tests meant to show it is an immunosuppressive drug.
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The Environmental Determinants of Diabetes in the Young
The Environmental Determinants of Diabetes in the Young is a longitudinal study examining the environmental causes of Type 1 diabetes(T1D), formerly known as juvenile diabetes.
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Twin
Twins are two offspring produced by the same pregnancy.
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Unified atomic mass unit
The unified atomic mass unit or dalton (symbol: u, or Da) is a standard unit of mass that quantifies mass on an atomic or molecular scale (atomic mass).
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United States Environmental Protection Agency
The Environmental Protection Agency is an independent agency of the United States federal government for environmental protection.
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Urinary tract infection
A urinary tract infection (UTI) is an infection that affects part of the urinary tract.
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Vitamin D
Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and multiple other biological effects.
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World Health Organization
The World Health Organization (WHO; French: Organisation mondiale de la santé) is a specialized agency of the United Nations that is concerned with international public health.
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Xeroderma
Xeroderma or xerodermia (also known as xerosis cutis), derived from the Greek words for "dry skin", is a condition involving the integumentary system, which in most cases can safely be treated with emollients or moisturizers.
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Xerostomia
Xerostomia, also known as dry mouth and dry mouth syndrome, is dryness in the mouth, which may be associated with a change in the composition of saliva, or reduced salivary flow, or have no identifiable cause.
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References
[1] https://en.wikipedia.org/wiki/Diabetes_mellitus_type_1
