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Dihydropyrimidine dehydrogenase

Index Dihydropyrimidine dehydrogenase

Dihydropyrimidine dehydrogenase (DPD) is an enzyme that is involved in pyrimidine degradation. [1]

7 relations: Dihydropyrimidine dehydrogenase deficiency, Enzyme, Fluorouracil, Pyrimidine, Tegafur, Thymine, Uracil.

Dihydropyrimidine dehydrogenase deficiency

Dihydropyrimidine dehydrogenase deficiency (DPD deficiency) is an autosomal recessive metabolic disorder in which there is absent or significantly decreased activity of dihydropyrimidine dehydrogenase, an enzyme involved in the metabolism of uracil and thymine.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Fluorouracil

Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a medication used to treat cancer.

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Pyrimidine

Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine.

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Tegafur

Tegafur (INN, BAN, USAN) is a chemotherapeutic prodrug of 5-fluorouracil (5-FU) used in the treatment of cancers.

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Thymine

---> Thymine (T, Thy) is one of the four nucleobases in the nucleic acid of DNA that are represented by the letters G–C–A–T.

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Uracil

Uracil (U) is one of the four nucleobases in the nucleic acid of RNA that are represented by the letters A, G, C and U. The others are adenine (A), cytosine (C), and guanine (G).

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Redirects here:

DihydroPyrimidine Dehydrogenase.

References

[1] https://en.wikipedia.org/wiki/Dihydropyrimidine_dehydrogenase

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