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DNA gyrase

Index DNA gyrase

DNA gyrase, or simply gyrase, is an enzyme within the class of topoisomerase (Type II topoisomerase) that relieves strain while double-stranded DNA is being unwound by helicase. [1]

24 relations: Adenosine triphosphate, Aminocoumarin, Antibiotic, Apicoplast, Bacteria, Carlos Bustamante, Ciprofloxacin, Competitive inhibition, DNA, DNA polymerase, DNA replication, DNA supercoil, Enzyme, Helicase, Linking number, Nalidixic acid, Novobiocin, Nucleic acid double helix, Plasmodium falciparum, Prokaryote, Quinolone antibiotic, Topoisomerase, Topoisomerase IV, Transcription (biology).

Adenosine triphosphate

Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.

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Aminocoumarin

Aminocoumarin is a class of antibiotics that act by an inhibition of the DNA gyrase enzyme involved in the cell division in bacteria.

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Antibiotic

An antibiotic (from ancient Greek αντιβιοτικά, antibiotiká), also called an antibacterial, is a type of antimicrobial drug used in the treatment and prevention of bacterial infections.

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Apicoplast

An apicoplast is a derived non-photosynthetic plastid found in most Apicomplexa, including Toxoplasma gondii, malaria parasites such as Plasmodium falciparum, but not in others such as Cryptosporidium.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Carlos Bustamante

Carlos José Bustamante (born 1951 in Lima, Peru) is an American scientist.

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Ciprofloxacin

Ciprofloxacin is an antibiotic used to treat a number of bacterial infections.

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Competitive inhibition

Competitive inhibition is a form of enzyme inhibition where binding of an inhibitor prevents binding of the target molecule of the enzyme, also known as the substrate.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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DNA polymerase

DNA polymerases are enzymes that synthesize DNA molecules from deoxyribonucleotides, the building blocks of DNA.

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DNA replication

In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.

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DNA supercoil

DNA supercoiling refers to the over- or under-winding of a DNA strand, and is an expression of the strain on that strand.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Helicase

Helicases are a class of enzymes vital to all living organisms.

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Linking number

In mathematics, the linking number is a numerical invariant that describes the linking of two closed curves in three-dimensional space.

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Nalidixic acid

Nalidixic acid (tradenames Nevigramon, Neggram, Wintomylon and WIN 18,320) is the first of the synthetic quinolone antibiotics.

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Novobiocin

Novobiocin, also known as albamycin or cathomycin, is an aminocoumarin antibiotic that is produced by the actinomycete Streptomyces niveus, which has recently been identified as a subjective synonym for S. spheroides a member of the order Actinobacteria.

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Nucleic acid double helix

In molecular biology, the term double helix refers to the structure formed by double-stranded molecules of nucleic acids such as DNA.

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Plasmodium falciparum

Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that cause malaria in humans.

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Prokaryote

A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.

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Quinolone antibiotic

A quinolone antibiotic is any member of a large group of broad-spectrum bactericides that share a bicyclic core structure related to the compound 4-quinolone.

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Topoisomerase

Topoisomerases are enzymes that participate in the overwinding or underwinding of DNA.

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Topoisomerase IV

Topoisomerase IV is one of two type-II topoisomerases in bacteria, the other being DNA gyrase.

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Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

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Redirects here:

DNA Gyrase, DNA girase, DNA topoisomerase (ATP-hydrolysing), DNA topoisomerase II, DNA-gyrase, Deoxyribonucleic topoisomerase, Dna gyrase, EC 5.99.1.3, GyrB, Gyrase, Type II DNA topoisomerase.

References

[1] https://en.wikipedia.org/wiki/DNA_gyrase

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