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79 relations: Actinic keratosis, Allopurinol, American Journal of Clinical Oncology, Anal cancer, Anaphylaxis, Angina, Antimetabolite, Ataxia, Autopharmacology, Basal-cell carcinoma, Bone marrow suppression, Bowen's disease, Breast cancer, British Approved Name, Cancer, Capecitabine, Cardiac arrest, Cardiotoxicity, Central nervous system, Cervical cancer, Charles Heidelberger, Chemotherapy-induced acral erythema, Clinical Journal of Oncology Nursing, Colorectal cancer, Coronary vasospasm, Cytochrome P450, Cytopenia, Developing country, Dihydropyrimidine dehydrogenase, Dihydropyrimidine dehydrogenase deficiency, DNA, DNA replication, Dysmetria, Encephalopathy, Esophageal cancer, Esophagitis, Fluoroacetic acid, Folinic acid, Genetic variation, Head and neck cancer, Health system, Heart arrhythmia, Hiccup, Hoffmann-La Roche, International nonproprietary name, Intravenous therapy, Kidney, Liver, Mucositis, Myelin, ..., National Health Service, Neurotoxicity, Neutropenia, Nucleoside, Nystagmus, Oligodendrocyte, Pancreatic cancer, Photophobia, Pregnancy, Proctitis, Pyrimidine analogue, Skin cancer, Sorivudine, Stomach cancer, Tegafur, Thrombocytopenia, Thymidine, Thymidine monophosphate, Thymidylate synthase, Thymidylate synthase inhibitor, Thymineless death, United States, United States Adopted Name, United States Pharmacopeia, Uracil, Ventricular tachycardia, Warfarin, WHO Model List of Essential Medicines, Zygosity. Expand index (29 more) »
Actinic keratosis
Actinic keratosis (AK) is a pre-cancerous patch of thick, scaly, or crusty skin.
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Allopurinol
Allopurinol, sold under the brand name Zyloprim among others, is a medication used to decrease high blood uric acid levels.
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American Journal of Clinical Oncology
The American Journal of Clinical Oncology is a bimonthly, peer-reviewed, scientific, oncology journal, published by Lippincott Williams & Wilkins.
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Anal cancer
Anal cancer is a cancer (malignant tumor) which arises from the anus, the distal opening of the gastrointestinal tract.
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Anaphylaxis
Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.
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Angina
Angina, also known as angina pectoris, is chest pain or pressure, usually due to not enough blood flow to the heart muscle.
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Antimetabolite
An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism.
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Ataxia
Ataxia is a neurological sign consisting of lack of voluntary coordination of muscle movements that includes gait abnormality.
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Autopharmacology
Autopharmacology relates to the scientific study of the regulation of body functions by the activity of its naturally existent (or endogenous) chemical factors of the tissues.
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Basal-cell carcinoma
Basal-cell carcinoma (BCC), also known as basal-cell cancer, is the most common type of skin cancer.
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Bone marrow suppression
Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).
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Bowen's disease
Bowen's disease, also known as squamous cell carcinoma in situJames, William; Berger, Timothy; Elston, Dirk (2005).
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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British Approved Name
A British Approved Name (BAN) is the official non-proprietary or generic name given to a pharmaceutical substance, as defined in the British Pharmacopoeia (BP).
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Capecitabine
Capecitabine, sold under the brand name Xeloda among others, is a chemotherapy medication used to treat breast cancer, gastric cancer and colorectal cancer.
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Cardiac arrest
Cardiac arrest is a sudden loss of blood flow resulting from the failure of the heart to effectively pump.
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Cardiotoxicity
Cardiotoxicity is the occurrence of heart electrophysiology dysfunction or muscle damage.
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Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
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Cervical cancer
Cervical cancer is a cancer arising from the cervix.
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Charles Heidelberger
Charles Heidelberger (December 23, 1920 – January 18, 1983) was a cancer researcher who developed and patented an anticancer drug called 5-Fluorouracil that remains widely used against cancers of the stomach, colon and breast.
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Chemotherapy-induced acral erythema
Chemotherapy-induced acral erythema (also known as palmar-plantar erythrodysesthesia, palmoplantar erythrodysesthesia, or hand-foot syndrome) is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
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Clinical Journal of Oncology Nursing
The Clinical Journal of Oncology Nursing is a bimonthly peer-reviewed nursing journal covering oncology nursing.
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Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
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Coronary vasospasm
Coronary vasospasm is a sudden, intense vasoconstriction of an epicardial coronary artery that causes occlusion (stoppage) or near-occlusion of the vessel.
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Cytochrome P450
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
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Cytopenia
Cytopenia is a reduction in the number of mature blood cells.
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Developing country
A developing country (or a low and middle income country (LMIC), less developed country, less economically developed country (LEDC), underdeveloped country) is a country with a less developed industrial base and a low Human Development Index (HDI) relative to other countries.
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Dihydropyrimidine dehydrogenase
Dihydropyrimidine dehydrogenase (DPD) is an enzyme that is involved in pyrimidine degradation.
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Dihydropyrimidine dehydrogenase deficiency
Dihydropyrimidine dehydrogenase deficiency (DPD deficiency) is an autosomal recessive metabolic disorder in which there is absent or significantly decreased activity of dihydropyrimidine dehydrogenase, an enzyme involved in the metabolism of uracil and thymine.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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DNA replication
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.
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Dysmetria
Dysmetria (wrong length) refers to a lack of coordination of movement typified by the undershoot or overshoot of intended position with the hand, arm, leg, or eye.
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Encephalopathy
Encephalopathy (from ἐγκέφαλος "brain" + πάθος "suffering") means any disorder or disease of the brain, especially chronic degenerative conditions.
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Esophageal cancer
Esophageal cancer is cancer arising from the esophagus—the food pipe that runs between the throat and the stomach.
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Esophagitis
Esophagitis (or oesophagitis) is an inflammation of the esophagus.
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Fluoroacetic acid
Fluoroacetic acid is a chemical compound with formula CH2FCOOH.
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Folinic acid
Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine.
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Genetic variation
Genetic variation means that biological systems – individuals and populations – are different over space.
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Head and neck cancer
Head and neck cancer is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands.
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Health system
A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.
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Heart arrhythmia
Heart arrhythmia (also known as arrhythmia, dysrhythmia, or irregular heartbeat) is a group of conditions in which the heartbeat is irregular, too fast, or too slow.
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Hiccup
A hiccup (also spelled hiccough) is an involuntary contraction (myoclonic jerk) of the diaphragm that may repeat several times per minute.
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Hoffmann-La Roche
F.
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International nonproprietary name
The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.
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Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
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Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Mucositis
Mucositis is the painful inflammation and ulceration of the mucous membranes lining the digestive tract, usually as an adverse effect of chemotherapy and radiotherapy treatment for cancer.
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Myelin
Myelin is a lipid-rich substance that surrounds the axon of some nerve cells, forming an electrically insulating layer.
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National Health Service
The National Health Service (NHS) is the name used for each of the public health services in the United Kingdom – the National Health Service in England, NHS Scotland, NHS Wales, and Health and Social Care in Northern Ireland – as well as a term to describe them collectively.
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Neurotoxicity
Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system.
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Neutropenia
Neutropenia or neutropaenia is an abnormally low concentration of neutrophils (a type of white blood cell) in the blood.
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Nucleoside
Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group.
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Nystagmus
Nystagmus is a condition of involuntary (or voluntary, in rare cases) eye movement, acquired in infancy or later in life, that may result in reduced or limited vision.
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Oligodendrocyte
Oligodendrocytes, or oligodendroglia,.
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Pancreatic cancer
Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass.
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Photophobia
Photophobia is a symptom of abnormal intolerance to visual perception of light.
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Pregnancy
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
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Proctitis
Proctitis is an inflammation of the anus and the lining of the rectum, affecting only the last 6 inches of the rectum.
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Pyrimidine analogue
Pyrimidine analogues are nucleoside analog antimetabolites which mimic the structure of metabolic pyrimidines.
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Skin cancer
Skin cancers are cancers that arise from the skin.
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Sorivudine
Sorivudine (INN), is a nucleoside analogue antiviral drug, marketed under trade names such as Usevir (Nippon Shoji, Eisai) and Brovavir (BMS).
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Stomach cancer
Stomach cancer, also known as gastric cancer, is cancer developing from the lining of the stomach.
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Tegafur
Tegafur (INN, BAN, USAN) is a chemotherapeutic prodrug of 5-fluorouracil (5-FU) used in the treatment of cancers.
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Thrombocytopenia
Thrombocytopenia is a condition characterized by abnormally low levels of thrombocytes, also known as platelets, in the blood.
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Thymidine
Thymidine (deoxythymidine; other names deoxyribosylthymine, thymine deoxyriboside) is a pyrimidine deoxynucleoside.
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Thymidine monophosphate
Thymidine monophosphate (TMP), also known as thymidylic acid (conjugate base thymidylate), deoxythymidine monophosphate (dTMP), or deoxythymidylic acid (conjugate base deoxythymidylate), is a nucleotide that is used as a monomer in DNA.
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Thymidylate synthase
Thymidylate synthetase is an enzyme that catalyzes the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP).
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Thymidylate synthase inhibitor
Thymidylate synthase inhibitors are chemical agents which inhibit the enzyme thymidylate synthase and have potential as an anticancer chemotherapy.
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Thymineless death
Thymineless death is the phenomenon by which bacteria, yeasts and mammalian cells undergo cell death when they are starved of thymidine triphosphate (dTTP), an essential precursor for DNA replication.
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United States
The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.
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United States Adopted Name
United States Adopted Names are unique nonproprietary names assigned to pharmaceuticals marketed in the United States.
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United States Pharmacopeia
The United States Pharmacopeia (USP) is a pharmacopeia (compendium of drug information) for the United States published annually by the United States Pharmacopeial Convention (usually also called the USP), a nonprofit organization that owns the trademark and copyright.
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Uracil
Uracil (U) is one of the four nucleobases in the nucleic acid of RNA that are represented by the letters A, G, C and U. The others are adenine (A), cytosine (C), and guanine (G).
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Ventricular tachycardia
Ventricular tachycardia (V-tach or VT) is a type of regular and fast heart rate that arises from improper electrical activity in the ventricles of the heart.
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Warfarin
Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant (blood thinner).
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WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
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Zygosity
Zygosity is the degree of similarity of the alleles for a trait in an organism.
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Redirects here:
5 Fluorouracil, 5 fluorouracil, 5 fu, 5-FU, 5-Fluorouracil, 5-Flurouracil, 5-flourouracil, 5-fluoro-uracil, 5-fluorouracil, 5-fluorouracil cream, 5-flurouricil, 5FU, 5fu, ATC code L01BC02, ATCvet code QL01BC02, Adrucil, Arumel, C4H3FN2O2, Carac, Carzonal, Effluderm, Efudex, Efudix, Efurix, F5U, Fluoroblastin, Fluoroplex, Fluororacil, Fluracil, Fluracilum, Fluri, Fluril, Fluro Uracil, Ftoruracil, Kecimeton, Phthoruracil, Phtoruracil, Queroplex, S-FU, Timazin, Ulup.
References
[1] https://en.wikipedia.org/wiki/Fluorouracil
