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Fertility factor (bacteria)

Index Fertility factor (bacteria)

The fertility factor (first named F by one of its discoverers Esther Lederberg) (also called the sex factor in E. Coli or the F sex factor) allows genes to be transferred from one bacterium carrying the factor to another bacterium lacking the factor by conjugation. The F factor is carried on the F episome, the first episome to be discovered. Unlike other plasmids, F factor is constitutive for transfer proteins due to the gene traJ. The F plasmid belongs to a class of conjugative plasmids that control sexual functions of bacteria with a fertility inhibition (Fin) system. [1]

21 relations: Bacterial artificial chromosome, Bacterial conjugation, Biological engineering, Escherichia coli, Esther Lederberg, FinP, FlmA-FlmB toxin-antitoxin system, Fosmid, Genetic recombination, Genome, Helicase, Hfr cell, Insertion sequence, Joshua Lederberg, Luigi Luca Cavalli-Sforza, Operon, Plasmid, TraJ 5' UTR, Transcription factor, Transfer gene, William Hayes (geneticist).

Bacterial artificial chromosome

A bacterial artificial chromosome (BAC) is a DNA construct, based on a functional fertility plasmid (or F-plasmid), used for transforming and cloning in bacteria, usually E. coli.

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Bacterial conjugation

Bacterial conjugation is the transfer of genetic material between bacterial cells by direct cell-to-cell contact or by a bridge-like connection between two cells.

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Biological engineering

Biological engineering or bio-engineering is the application of principles of biology and the tools of engineering to create usable, tangible, economically viable products.

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Escherichia coli

Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).

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Esther Lederberg

Esther Miriam Zimmer Lederberg (December 18, 1922 – November 11, 2006) was an American microbiologist and a pioneer of bacterial genetics.

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FinP

FinP encodes an antisense non-coding RNA gene that is complementary to part of the TraJ 5' UTR.

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FlmA-FlmB toxin-antitoxin system

The FlmA-FlmB toxin-antitoxin system consists of FlmB RNA (F leading-region maintenance B), a family of non-coding RNAs and the protein toxin FlmA.

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Fosmid

Fosmids are similar to cosmids but are based on the bacterial F-plasmid.

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Genetic recombination

Genetic recombination (aka genetic reshuffling) is the production of offspring with combinations of traits that differ from those found in either parent.

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Genome

In the fields of molecular biology and genetics, a genome is the genetic material of an organism.

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Helicase

Helicases are a class of enzymes vital to all living organisms.

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Hfr cell

A high-frequency recombination cell (Hfr cell) (also called an Hfr strain) is a bacterium with a conjugative plasmid (for example, the F-factor) integrated into its chromosomal DNA.

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Insertion sequence

Insertion element (also known as an IS, an insertion sequence element, or an IS element) is a short DNA sequence that acts as a simple transposable element.

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Joshua Lederberg

Joshua Lederberg, ForMemRS (May 23, 1925 – February 2, 2008) was an American molecular biologist known for his work in microbial genetics, artificial intelligence, and the United States space program.

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Luigi Luca Cavalli-Sforza

Luigi Luca Cavalli-Sforza (born 25 January 1922) is an Italian-born population geneticist, who has been a professor (now emeritus) at Stanford University since 1970.

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Operon

In genetics, an operon is a functioning unit of DNA containing a cluster of genes under the control of a single promoter.

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Plasmid

A plasmid is a small DNA molecule within a cell that is physically separated from a chromosomal DNA and can replicate independently.

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TraJ 5' UTR

The traJ 5' UTR is a cis acting RNA element which is involved in regulating plasmid transfer in bacteria.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Transfer gene

Transfer operon, commonly called tra operon, or tra genes, are some genes necessary for non-sexual transfer of genetic material in both gram-positive and gram-negative bacteria.

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William Hayes (geneticist)

Prof William Hayes FRS FRSE LLD (18 January 1913 – 7 January 1994) was an Irish geneticist.

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Redirects here:

F plasmid, F' episome, F' factor, F'-episome, F'-plasmid, F- cell, F-plasmid, Sex factor.

References

[1] https://en.wikipedia.org/wiki/Fertility_factor_(bacteria)

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