6 relations: Cellular differentiation, Embryonic stem cell, KLF4, Myc, Oct-4, SOX2.
Cellular differentiation
In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.
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Embryonic stem cell
Embryonic stem cells (ES cells or ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre-implantation embryo.
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KLF4
Kruppel-like factor 4 (KLF4; gut-enriched Krüppel-like factor or GKLF) is a zinc-finger transcription factor, and it was first identified in 1996.
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Myc
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors.
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Oct-4
Oct-4 (octamer-binding transcription factor 4), also known as POU5F1 (POU domain, class 5, transcription factor 1), is a protein that in humans is encoded by the POU5F1 gene.
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SOX2
SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential for maintaining self-renewal, or pluripotency, of undifferentiated embryonic stem cells.
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