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Gcn2

Index Gcn2

GCN2 (general control nonderepressible 2) is a serine/threonine-protein kinase that senses amino acid deficiency through binding to uncharged transfer RNA (tRNA). [1]

36 relations: ATF4, Caenorhabditis elegans, Cell cycle, Drosophila melanogaster, EIF-2 kinase, EIF2, EIF2AK1, EIF2AK3, EIF2AK4, EIF2B, EIF2S1, EIF2S2, EIF2S3, Eukaryotic initiation factor, Eukaryotic small ribosomal subunit (40S), Fatty acid synthase, Guanine nucleotide exchange factor, Guanosine diphosphate, Guanosine triphosphate, HARS, Messenger RNA, Methyl methanesulfonate, Neurospora crassa, Nitric oxide, Nitric oxide synthase, Open reading frame, Piriform cortex, Pre-replication complex, Protein kinase R, Restriction point, Ribosome, Saccharomyces cerevisiae, Serine/threonine-specific protein kinase, Sterol regulatory element-binding protein, Transfer RNA, Upstream open reading frame.

ATF4

Activating transcription factor 4 (tax-responsive enhancer element B67), also known as ATF4, is a protein that in humans is encoded by the ATF4 gene.

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Caenorhabditis elegans

Caenorhabditis elegans is a free-living (not parasitic), transparent nematode (roundworm), about 1 mm in length, that lives in temperate soil environments.

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Cell cycle

The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.

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Drosophila melanogaster

Drosophila melanogaster is a species of fly (the taxonomic order Diptera) in the family Drosophilidae.

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EIF-2 kinase

eIF-2 is a kinase enzyme that phosphorylates eIF-2.

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EIF2

Eukaryotic Initiation Factor 2 (eIF2) is a eukaryotic initiation factor.

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EIF2AK1

Eukaryotic translation initiation factor 2-alpha kinase 1 is an enzyme that in humans is encoded by the EIF2AK1 gene.

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EIF2AK3

Eukaryotic translation initiation factor 2-alpha kinase 3, also known as protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK), is an enzyme that in humans is encoded by the EIF2AK3 gene.

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EIF2AK4

Eukaryotic translation initiation factor 2-alpha kinase 4 is an enzyme that in humans is encoded by the EIF2AK4 gene.

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EIF2B

eIF2B is a protein found in eukaryotes.

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EIF2S1

Eukaryotic translation initiation factor 2 subunit 1 (eIF2α) is a protein that in humans is encoded by the EIF2S1 gene.

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EIF2S2

Eukaryotic translation initiation factor 2 subunit 2 (eIF2β) is a protein that in humans is encoded by the EIF2S2 gene.

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EIF2S3

Eukaryotic translation initiation factor 2 subunit 3 (eIF2γ) is a protein that in humans is encoded by the EIF2S3 gene.

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Eukaryotic initiation factor

Eukaryotic initiation factors (eIFs) are proteins or protein complexes involved in the initiation phase of eukaryotic translation.

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Eukaryotic small ribosomal subunit (40S)

The eukaryotic small ribosomal subunit (40S) is the smaller subunit of the eukaryotic 80S ribosomes, with the other major component being the large ribosomal subunit (60S).

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Fatty acid synthase

Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene.

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Guanine nucleotide exchange factor

Guanine nucleotide exchange factors (GEFs) are proteins or protein domains that activate monomeric GTPases by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP).

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Guanosine diphosphate

Guanosine diphosphate, abbreviated GDP, is a nucleoside diphosphate.

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Guanosine triphosphate

Guanosine-5'-triphosphate (GTP) is a purine nucleoside triphosphate.

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HARS

Histidyl-tRNA synthetase (HARS) also known as histidine-tRNA ligase, is an enzyme which in humans is encoded by the HARS gene.

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Messenger RNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

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Methyl methanesulfonate

Methyl methanesulfonate (MMS), also known as methyl mesylate, is an alkylating agent and a carcinogen.

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Neurospora crassa

Neurospora crassa is a type of red bread mold of the phylum Ascomycota.

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Nitric oxide

Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula NO.

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Nitric oxide synthase

Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine.

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Open reading frame

In molecular genetics, an open reading frame (ORF) is the part of a reading frame that has the ability to be translated.

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Piriform cortex

The piriform cortex, or pyriform cortex, is a region in the brain, part of the rhinencephalon situated in the cerebrum.

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Pre-replication complex

A pre-replication complex (pre-RC) is a protein complex that forms at the origin of replication during the initiation step of DNA replication.

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Protein kinase R

Protein kinase RNA-activated also known as protein kinase R (PKR), interferon-induced, double-stranded RNA-activated protein kinase, or eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) is an enzyme that in humans is encoded by the EIF2AK2 gene.

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Restriction point

The restriction point (R) is a point in G1 of the animal cell cycle at which the cell becomes "committed" to the cell cycle and after which extracellular proliferation stimulants are no longer required.

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Ribosome

The ribosome is a complex molecular machine, found within all living cells, that serves as the site of biological protein synthesis (translation).

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Saccharomyces cerevisiae

Saccharomyces cerevisiae is a species of yeast.

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Serine/threonine-specific protein kinase

A serine/threonine protein kinase is a kinase enzyme that phosphorylates the OH group of serine or threonine (which have similar sidechains).

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Sterol regulatory element-binding protein

Sterol regulatory element-binding proteins (SREBPs) are transcription factors that bind to the sterol regulatory element DNA sequence TCACNCCAC.

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Transfer RNA

A transfer RNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length, that serves as the physical link between the mRNA and the amino acid sequence of proteins.

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Upstream open reading frame

An Upstream Open Reading Frame (uORF) is an open reading frame (ORF) within the 5' untranslated region (5'UTR) of an mRNA.

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References

[1] https://en.wikipedia.org/wiki/Gcn2

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