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Gene regulatory network

Index Gene regulatory network

A gene (or genetic) regulatory network (GRN) is a collection of molecular regulators that interact with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins. [1]

83 relations: Adaptation, Ansatz, Arabinose, Artificial neural network, Attractor, Bacteria, Bayesian network, Bifurcation theory, Body plan, Boolean function, Boolean network, Caenorhabditis, Caister Academic Press, Cancer, Cell membrane, Cellular differentiation, Chaos theory, Chromatin, Cis-regulatory module, Convergent evolution, Critical point (mathematics), Differential equation, Diffusion, Directed graph, DNA, Drosophila, Dynamical system, Embryogenesis, Enzyme, Epigenesis (biology), Epigenetics, Escherichia coli, Evolutionary developmental biology, Feedback, Fixed point (mathematics), Galactose, Gene duplication, Gene expression, GeneNetwork, Gillespie algorithm, Hill equation (biochemistry), Hippo signaling pathway, Information processing, James Collins (bioengineer), Journal of Theoretical Biology, Mathematical model, Messenger RNA, Michaelis–Menten kinetics, Modularity (biology), Morphogen, ..., Morphogenesis, Network motif, Network topology, Nonlinear system, Operon, Ordinary differential equation, Oscillation, Petri net, Pleiotropy, Polynomial, Preferential attachment, Process calculus, Promoter (genetics), Protein, Rate equation, Reaction rate, Recurrent neural network, RNA, Scale-free network, Signal transduction, Stability theory, Steady state, Steady state (biochemistry), Stochastic, Stochastic differential equation, Stuart Kauffman, Synexpression, Systems biology, Time series, Transcription factor, Vertex (graph theory), Weighted correlation network analysis, Xenopus. Expand index (33 more) »

Adaptation

In biology, adaptation has three related meanings.

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Ansatz

In physics and mathematics, an ansatz (meaning: "initial placement of a tool at a work piece", plural ansätze; or ansatzes) is an educated guessIn his book on "The Nature of Mathematical Modelling", Neil Gershenfeld introduces ansatz, with interpretation "a trial answer", to be an important technique for solving differential equations.

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Arabinose

Arabinose is an aldopentose – a monosaccharide containing five carbon atoms, and including an aldehyde (CHO) functional group.

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Artificial neural network

Artificial neural networks (ANNs) or connectionist systems are computing systems vaguely inspired by the biological neural networks that constitute animal brains.

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Attractor

In the mathematical field of dynamical systems, an attractor is a set of numerical values toward which a system tends to evolve, for a wide variety of starting conditions of the system.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Bayesian network

A Bayesian network, Bayes network, belief network, Bayes(ian) model or probabilistic directed acyclic graphical model is a probabilistic graphical model (a type of statistical model) that represents a set of variables and their conditional dependencies via a directed acyclic graph (DAG).

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Bifurcation theory

Bifurcation theory is the mathematical study of changes in the qualitative or topological structure of a given family, such as the integral curves of a family of vector fields, and the solutions of a family of differential equations.

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Body plan

A body plan, Bauplan (German plural Baupläne), or ground plan is a set of morphological features common to many members of a phylum of animals.

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Boolean function

In mathematics and logic, a (finitary) Boolean function (or switching function) is a function of the form ƒ: Bk → B, where B.

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Boolean network

A Boolean network consists of a discrete set of Boolean variables each of which has a Boolean function (possibly different for each variable) assigned to it which takes inputs from a subset of those variables and output that determines the state of the variable it is assigned to.

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Caenorhabditis

Caenorhabditis is a genus of nematodes which live in bacteria-rich environments like compost piles, decaying dead animals and rotting fruit.

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Caister Academic Press

Caister Academic Press is an independent academic publishing company that produces books and ebooks on microbiology, and molecular biology.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Cellular differentiation

In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.

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Chaos theory

Chaos theory is a branch of mathematics focusing on the behavior of dynamical systems that are highly sensitive to initial conditions.

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Chromatin

Chromatin is a complex of macromolecules found in cells, consisting of DNA, protein, and RNA.

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Cis-regulatory module

Cis-regulatory module (CRM) is a stretch of DNA, usually 100–1000 DNA base pairs in length, where a number of transcription factors can bind and regulate expression of nearby genes and regulate their transcription rates.

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Convergent evolution

Convergent evolution is the independent evolution of similar features in species of different lineages.

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Critical point (mathematics)

In mathematics, a critical point or stationary point of a differentiable function of a real or complex variable is any value in its domain where its derivative is 0.

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Differential equation

A differential equation is a mathematical equation that relates some function with its derivatives.

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Diffusion

Diffusion is the net movement of molecules or atoms from a region of high concentration (or high chemical potential) to a region of low concentration (or low chemical potential) as a result of random motion of the molecules or atoms.

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Directed graph

In mathematics, and more specifically in graph theory, a directed graph (or digraph) is a graph that is a set of vertices connected by edges, where the edges have a direction associated with them.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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Drosophila

Drosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit.

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Dynamical system

In mathematics, a dynamical system is a system in which a function describes the time dependence of a point in a geometrical space.

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Embryogenesis

Embryogenesis is the process by which the embryo forms and develops.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Epigenesis (biology)

In biology, epigenesis (or, in contrast to preformationism, neoformationism) is the process by which plants, animals and fungi develop from a seed, spore or egg through a sequence of steps in which cells differentiate and organs form.

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Epigenetics

Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence.

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Escherichia coli

Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).

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Evolutionary developmental biology

Evolutionary developmental biology (informally, evo-devo) is a field of biological research that compares the developmental processes of different organisms to infer the ancestral relationships between them and how developmental processes evolved.

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Feedback

Feedback occurs when outputs of a system are routed back as inputs as part of a chain of cause-and-effect that forms a circuit or loop.

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Fixed point (mathematics)

In mathematics, a fixed point (sometimes shortened to fixpoint, also known as an invariant point) of a function is an element of the function's domain that is mapped to itself by the function.

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Galactose

Galactose (galacto- + -ose, "milk sugar"), sometimes abbreviated Gal, is a monosaccharide sugar that is about as sweet as glucose, and about 30% as sweet as sucrose.

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Gene duplication

Gene duplication (or chromosomal duplication or gene amplification) is a major mechanism through which new genetic material is generated during molecular evolution.

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.

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GeneNetwork

GeneNetwork is a combined database and open source bioinformatics data analysis software resource for systems genetics.

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Gillespie algorithm

In probability theory, the Gillespie algorithm (or occasionally the Doob-Gillespie algorithm) generates a statistically correct trajectory (possible solution) of a stochastic equation.

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Hill equation (biochemistry)

No description.

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Hippo signaling pathway

The Hippo signaling pathway, also known as the Salvador/Warts/Hippo (SWH) pathway, controls organ size in animals through the regulation of cell proliferation and apoptosis.

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Information processing

Information processing is the change (processing) of information in any manner detectable by an observer.

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James Collins (bioengineer)

James J. Collins (born June 26, 1965) is an American bioengineer, and the Termeer Professor of Medical Engineering & Science and Professor of Biological Engineering at MIT.

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Journal of Theoretical Biology

The Journal of Theoretical Biology is a biweekly peer-reviewed scientific journal covering theoretical biology, as well as mathematical and computational aspects of biology.

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Mathematical model

A mathematical model is a description of a system using mathematical concepts and language.

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Messenger RNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

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Michaelis–Menten kinetics

Michaelis–Menten saturation curve for an enzyme reaction showing the relation between the substrate concentration and reaction rate. In biochemistry, Michaelis–Menten kinetics is one of the best-known models of enzyme kinetics.

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Modularity (biology)

Modularity refers to the ability of a system to organize discrete, individual units that can overall increase the efficiency of network activity and, in a biological sense, facilitates selective forces upon the network.

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Morphogen

A morphogen is a substance whose non-uniform distribution governs the pattern of tissue development in the process of morphogenesis or pattern formation, one of the core processes of developmental biology, establishing positions of the various specialized cell types within a tissue.

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Morphogenesis

Morphogenesis (from the Greek morphê shape and genesis creation, literally, "beginning of the shape") is the biological process that causes an organism to develop its shape.

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Network motif

All networks, including biological networks, social networks, technological networks (e.g., computer networks and electrical circuits) and more, can be represented as graphs, which include a wide variety of subgraphs.

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Network topology

Network topology is the arrangement of the elements (links, nodes, etc.) of a communication network.

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Nonlinear system

In mathematics and science, a nonlinear system is a system in which the change of the output is not proportional to the change of the input.

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Operon

In genetics, an operon is a functioning unit of DNA containing a cluster of genes under the control of a single promoter.

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Ordinary differential equation

In mathematics, an ordinary differential equation (ODE) is a differential equation containing one or more functions of one independent variable and its derivatives.

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Oscillation

Oscillation is the repetitive variation, typically in time, of some measure about a central value (often a point of equilibrium) or between two or more different states.

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Petri net

A Petri net, also known as a place/transition (PT) net, is one of several mathematical modeling languages for the description of distributed systems.

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Pleiotropy

Pleiotropy (from Greek πλείων pleion, "more", and τρόπος tropos, "way") occurs when one gene influences two or more seemingly unrelated phenotypic traits.

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Polynomial

In mathematics, a polynomial is an expression consisting of variables (also called indeterminates) and coefficients, that involves only the operations of addition, subtraction, multiplication, and non-negative integer exponents of variables.

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Preferential attachment

A preferential attachment process is any of a class of processes in which some quantity, typically some form of wealth or credit, is distributed among a number of individuals or objects according to how much they already have, so that those who are already wealthy receive more than those who are not.

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Process calculus

In computer science, the process calculi (or process algebras) are a diverse family of related approaches for formally modelling concurrent systems.

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Promoter (genetics)

In genetics, a promoter is a region of DNA that initiates transcription of a particular gene.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Rate equation

The rate law or rate equation for a chemical reaction is an equation that links the reaction rate with the concentrations or pressures of the reactants and constant parameters (normally rate coefficients and partial reaction orders).

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Reaction rate

The reaction rate or rate of reaction is the speed at which reactants are converted into products.

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Recurrent neural network

A recurrent neural network (RNN) is a class of artificial neural network where connections between nodes form a directed graph along a sequence.

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RNA

Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.

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Scale-free network

A scale-free network is a network whose degree distribution follows a power law, at least asymptotically.

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Signal transduction

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.

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Stability theory

In mathematics, stability theory addresses the stability of solutions of differential equations and of trajectories of dynamical systems under small perturbations of initial conditions.

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Steady state

In systems theory, a system or a process is in a steady state if the variables (called state variables) which define the behavior of the system or the process are unchanging in time.

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Steady state (biochemistry)

In ionic steady state, cells maintain different internal and external concentrations of various ionic species.

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Stochastic

The word stochastic is an adjective in English that describes something that was randomly determined.

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Stochastic differential equation

A stochastic differential equation (SDE) is a differential equation in which one or more of the terms is a stochastic process, resulting in a solution which is also a stochastic process.

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Stuart Kauffman

Stuart Alan Kauffman (born September 28, 1939) is an American medical doctor, theoretical biologist, and complex systems researcher who studies the origin of life on Earth.

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Synexpression

Synexpression is a type of non-random eukaryotic gene organization.

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Systems biology

Systems biology is the computational and mathematical modeling of complex biological systems.

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Time series

A time series is a series of data points indexed (or listed or graphed) in time order.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Vertex (graph theory)

In mathematics, and more specifically in graph theory, a vertex (plural vertices) or node is the fundamental unit of which graphs are formed: an undirected graph consists of a set of vertices and a set of edges (unordered pairs of vertices), while a directed graph consists of a set of vertices and a set of arcs (ordered pairs of vertices).

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Weighted correlation network analysis

Weighted correlation network analysis, also known as weighted gene co-expression network analysis (WGCNA), is a widely used data mining method especially for studying biological networks based on pairwise correlations between variables.

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Xenopus

Xenopus (Gk., ξενος, xenos.

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Boolean regulatory networks, Gene network, Gene networks, Gene regulatory networks, Genetic network, Genetic networks, Genetic pathway, Genetic regulatory network, Genetic regulatory networks, Transcription network.

References

[1] https://en.wikipedia.org/wiki/Gene_regulatory_network

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