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134 relations: Acetylcholine receptor, Acrivastine, Adelaide, Adrenaline, Adrenergic receptor, Adverse drug reaction, Alimemazine, Allergen, Allergy, Anaphylaxis, Angioedema, Antazoline, Antibody, Anticholinergic, Antigen, Antihistamine, Antipsychotic, Anxiety, Astemizole, Atopic dermatitis, Australian Medicines Handbook, Azelastine, Basophil, Benzodiazepine, Bepotastine, Bilastine, Blood–brain barrier, Bradycardia, Bromazine, Brompheniramine, Bronchoconstriction, Bupropion, Carbinoxamine, Central nervous system, Cetirizine, Chlorcyclizine, Chloropyramine, Chlorphenamine, Clemastine, Conjunctivitis, Constipation, Contact dermatitis, Cyclizine, Cyproheptadine, Daniel Bovet, Degranulation, Desloratadine, Dexbrompheniramine, Dexchlorpheniramine, Diarrhea, ..., Dimenhydrinate, Dimetindene, Diphenhydramine, Doxylamine, Ebastine, Efficacy, Enantiomer, Epinephrine autoinjector, Ernest Fourneau, Ethanolamine, Ethylenediamine, Euphoria, Fexofenadine, Flushing (physiology), Guinea pig, Hagerstown, Maryland, Hallucination, Headache, Heart arrhythmia, Histamine, Histamine H1 receptor, Histamine receptor, Hives, Human eye, Human nose, Human skin, Hydroxyzine, Hypotension, Immunoglobulin E, Insomnia, Inverse agonist, Isomer, Itch, Ketotifen, Levocabastine, Levocetirizine, Lippincott Williams & Wilkins, Loratadine, Mast cell, Meclizine, Medication, Mepyramine, Metabolite, Methapyrilene, Mizolastine, Nausea, Nobel Prize in Physiology or Medicine, Olopatadine, Orphenadrine, Over-the-counter drug, Palpitations, Paris, Pasteur Institute, Phenindamine, Pheniramine, Phenothiazine, Phenyltoloxamine, Piperoxan, Promethazine, Psychoactive drug, Psychosis, Quifenadine, Receptor antagonist, Rhinitis, Rhinorrhea, Rupatadine, Skin, Substituted piperazine, Terfenadine, Tetracyclic antidepressant, Thenyldiamine, Thonzylamine, Tinnitus, Tricyclic, Tricyclic antidepressant, Tripelennamine, Triprolidine, United States, Vascular permeability, Vasodilation, Weight gain, Zwitterion, 5-HT receptor, 8-Chlorotheophylline. Expand index (84 more) »
Acetylcholine receptor
An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.
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Acrivastine
Acrivastine is a medication used for the treatment of allergies and hay fever.
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Adelaide
Adelaide is the capital city of the state of South Australia, and the fifth-most populous city of Australia.
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Adrenaline
Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.
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Adrenergic receptor
The adrenergic receptors (or adrenoceptors) are a class of G protein-coupled receptors that are targets of the catecholamines, especially norepinephrine (noradrenaline) and epinephrine (adrenaline).
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Adverse drug reaction
An adverse drug reaction (ADR) is an injury caused by taking a medication.
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Alimemazine
Alimemazine (INN), also known as trimeprazine,; brand names Nedeltran, Panectyl, Repeltin, Therafene, Theraligene, Theralen, Theralene, Vallergan, Vanectyl, and Temaril), commonly provided as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting as an antihistamine). It also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness. Although it is structurally related to drugs such as chlorpromazine, it is not used as an antipsychotic. In the Russian Federation, it is marketed under the brand name Teraligen for the treatment of anxiety disorders (including GAD), organic mood disorders, sleep disturbances, personality disorders accompanied by asthenia and depression, somatoform autonomic dysfunction and various neuroses. Alimemazine is not approved for use in humans in the United States. The combination of alimemazine and prednisolone (commonly sold under the brand name Temaril-P) is licensed as an antipruritic and antitussive in dogs.
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Allergen
An allergen is a type of antigen that produces an abnormally vigorous immune response in which the immune system fights off a perceived threat that would otherwise be harmless to the body.
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Allergy
Allergies, also known as allergic diseases, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.
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Anaphylaxis
Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.
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Angioedema
Angioedema is an area of swelling of the lower layer of skin and tissue just under the skin or mucous membranes.
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Antazoline
Antazoline is a 1st generation antihistamine with anticholinergic properties used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis.
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Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
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Anticholinergic
An anticholinergic agent is a substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system.
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Antigen
In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.
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Antihistamine
Antihistamines are drugs which treat allergic rhinitis and other allergies.
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Antipsychotic
Antipsychotics, also known as neuroleptics or major tranquilizers, are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder.
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Anxiety
Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behaviour such as pacing back and forth, somatic complaints, and rumination.
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Astemizole
Astemizole (marketed under the brand name Hismanal, developmental code R43512) was a second-generation antihistamine drug that has a long duration of action.
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Atopic dermatitis
Atopic dermatitis (AD), also known as atopic eczema, is a type of inflammation of the skin (dermatitis).
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Australian Medicines Handbook
Australian Medicines Handbook (AMH) is a peer-reviewed medicines prescribing guide for Australian health professionals.
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Azelastine
Azelastine is a potent, second-generation, selective, histamine antagonist (histamine-H1-receptor antagonist) used as a first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis).
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Basophil
Basophils are a type of white blood cells.
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Benzodiazepine
Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.
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Bepotastine
Bepotastine (Talion, Bepreve) is a 2nd generation antihistamine.
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Bilastine
Bilastine, sold under the brand name Bilaxten among others, is a second-generation antihistamine medication which is used in the treatment of allergic rhinoconjunctivitis and urticaria (hives).
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Blood–brain barrier
The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).
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Bradycardia
Bradycardia is a condition wherein an individual has a very slow heart rate, typically defined as a resting heart rate of under 60 beats per minute (BPM) in adults.
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Bromazine
Bromazine (trade names Ambodryl, Ambrodil and others), also known as bromodiphenhydramine, is an antihistamine and anticholinergic.
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Brompheniramine
Brompheniramine (Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane), commonly marketed as its salt brompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class.
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Bronchoconstriction
Bronchoconstriction is the constriction of the airways in the lungs due to the tightening of surrounding smooth muscle, with consequent coughing, wheezing, and shortness of breath.
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Bupropion
Bupropion, sold under the brand names Wellbutrin and Zyban among others, is a medication primarily used as an antidepressant and smoking cessation aid.
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Carbinoxamine
Carbinoxamine (Clistin, Palgic, Rondec, Rhinopront) is a antihistamine and anticholinergic agent.
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Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
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Cetirizine
Cetirizine, prominently marketed under the brand name Zyrtec among others, is a potent second-generation antihistamine used in the treatment of hay fever, allergies, angioedema, and urticaria.
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Chlorcyclizine
Chlorcyclizine (Di-Paralene, Mantadil, Pruresidine, Trihistan) is a first-generation antihistamine of the diphenylmethylpiperazine group marketed in the United States and certain other countries.
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Chloropyramine
Chloropyramine is a classical ("old", or first-generation) antihistamine drug approved in some Eastern European countries (like Russia) for the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions.
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Chlorphenamine
Chlorphenamine (also known as chlorpheniramine, CP, or CPM) is a first-generation antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria.
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Clemastine
Clemastine, also known as meclastin, is an antihistamine and anticholinergic.
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Conjunctivitis
Conjunctivitis, also known as pink eye, is inflammation of the outermost layer of the white part of the eye and the inner surface of the eyelid.
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Constipation
Constipation refers to bowel movements that are infrequent or hard to pass.
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Contact dermatitis
Contact dermatitis is a type of inflammation of the skin.
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Cyclizine
Cyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo.
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Cyproheptadine
Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties.
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Daniel Bovet
Daniel Bovet (23 March 1907 – 8 April 1992) was a Swiss-born Italian pharmacologist who won the 1957 Nobel Prize in Physiology or Medicine for his discovery of drugs that block the actions of specific neurotransmitters.
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Degranulation
Degranulation is a cellular process that releases antimicrobial cytotoxic or other molecules from secretory vesicles called granules found inside some cells.
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Desloratadine
Desloratadine (trade name Clarinex in the US and Aerius in Europe and Canada) is a tricyclic H1-antihistamine that is used to treat allergies.
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Dexbrompheniramine
Dexbrompheniramine is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.
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Dexchlorpheniramine
Dexchlorpheniramine (trade name Polaramine) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.
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Diarrhea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose or liquid bowel movements each day.
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Dimenhydrinate
Dimenhydrinate, marketed as Dramamine and Gravol among others, is an over-the-counter medication used to treat motion sickness and nausea.
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Dimetindene
Dimetindene (trade name Fenistil; other name dimethindene maleate) is an antiallergic drug.
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Diphenhydramine
Diphenhydramine is an antihistamine mainly used to treat allergies.
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Doxylamine
Doxylamine is a first-generation antihistamine.
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Ebastine
Ebastine (trade names Evastin, Atmos, Kestine, Ebastel, Aleva, Ebatrol) is a H1 antihistamine with low potential for causing drowsiness.
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Efficacy
Efficacy is the ability to get a job done satisfactorily.
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Enantiomer
In chemistry, an enantiomer, also known as an optical isomer (and archaically termed antipode or optical antipode), is one of two stereoisomers that are mirror images of each other that are non-superposable (not identical), much as one's left and right hands are the same except for being reversed along one axis (the hands cannot be made to appear identical simply by reorientation).
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Epinephrine autoinjector
An epinephrine autoinjector is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology.
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Ernest Fourneau
Ernest Fourneau (4 October 1872 – 5 August 1949) was a French medicinal chemist who played a major role in the discovery of synthetic local anesthetics, as well as in the synthesis of suramin.
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Ethanolamine
Ethanolamine (2-aminoethanol, monoethanolamine, ETA, or MEA) is an organic chemical compound with the formula HOCH2CH2NH2.
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Ethylenediamine
Ethylenediamine (abbreviated as en when a ligand) is the organic compound with the formula C2H4(NH2)2.
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Euphoria
Euphoria is an affective state in which a person experiences pleasure or excitement and intense feelings of well-being and happiness.
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Fexofenadine
Fexofenadine, sold under the trade name Allegra among others is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria.
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Flushing (physiology)
For a person to flush is to become markedly red in the face and often other areas of the skin, from various physiological conditions.
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Guinea pig
The guinea pig or domestic guinea pig (Cavia porcellus), also known as cavy or domestic cavy, is a species of rodent belonging to the family Caviidae and the genus Cavia.
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Hagerstown, Maryland
Hagerstown is a city in Washington County, Maryland, United States.
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Hallucination
A hallucination is a perception in the absence of external stimulus that has qualities of real perception.
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Headache
Headache is the symptom of pain anywhere in the region of the head or neck.
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Heart arrhythmia
Heart arrhythmia (also known as arrhythmia, dysrhythmia, or irregular heartbeat) is a group of conditions in which the heartbeat is irregular, too fast, or too slow.
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Histamine
Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.
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Histamine H1 receptor
The H1 receptor is a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors.
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Histamine receptor
The histamine receptors are a class of G protein–coupled receptors which bind histamine as their primary endogenous ligand.
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Hives
Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps.
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Human eye
The human eye is an organ which reacts to light and pressure.
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Human nose
The human nose is the protruding part of the face that bears the nostrils.
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Human skin
The human skin is the outer covering of the body.
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Hydroxyzine
Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is a first-generation antihistamine.
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Hypotension
Hypotension is low blood pressure, especially in the arteries of the systemic circulation.
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Immunoglobulin E
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals.
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Insomnia
Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.
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Inverse agonist
In the field of pharmacology, an inverse agonist is an agent that binds to the same receptor as an agonist but induces a pharmacological response opposite to that agonist.
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Isomer
An isomer (from Greek ἰσομερής, isomerès; isos.
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Itch
Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch.
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Ketotifen
Ketotifen, sold under the brand name Zaditor among others, is a first-generation noncompetitive H1-antihistamine and mast cell stabilizer.
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Levocabastine
Levocabastine (trade name Livostin) is a selective second-generation H1 receptor antagonists which was discovered at Janssen Pharmaceutica in 1979.
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Levocetirizine
Levocetirizine (as levocetirizine dihydrochloride) is a third-generation, non-sedating antihistamine, developed from the second-generation antihistamine cetirizine.
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Lippincott Williams & Wilkins
Lippincott Williams & Wilkins (LWW) is an imprint of the publishing conglomerate Wolters Kluwer.
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Loratadine
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies.
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Mast cell
A mast cell (also known as a mastocyte or a labrocyte) is a type of white blood cell.
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Meclizine
Meclizine (INN, or meclozine) is an antihistamine of the diphenylmethylpiperazine group considered to be an antiemetic.
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Medication
A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.
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Mepyramine
Mepyramine, also known as pyrilamine, is a first generation antihistamine, targeting the H1 receptor.
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Metabolite
A metabolite is the intermediate end product of metabolism.
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Methapyrilene
Methapyrilene is an antihistamine and anticholinergic of the pyridine chemical class which was developed in the early 1950s.
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Mizolastine
Mizolastine (Mizollen) is a once-daily, non-sedating antihistamine.
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Nausea
Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.
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Nobel Prize in Physiology or Medicine
The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin), administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the fields of life sciences and medicine.
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Olopatadine
Olopatadine is an antihistamine (as well as anticholinergic and mast cell stabilizer), sold as a prescription eye drop manufactured by Alcon in one of three strengths: 0.7% solution or Pazeo in the United States, 0.2% solution or Pataday (also called Patanol S in some countries), and 0.1% or Patanol (also called Opatanol in some countries; Olopat in India).
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Orphenadrine
Orphenadrine (sold under many brand names worldwide Page accessed Feb 5, 2016) is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine.
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Over-the-counter drug
Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a prescription from a healthcare professional, as opposed to prescription drugs, which may be sold only to consumers possessing a valid prescription.
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Palpitations
Palpitations are the perceived abnormality of the heartbeat characterized by awareness of cardiac muscle contractions in the chest: hard, fast and/or irregular beats.
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Paris
Paris is the capital and most populous city of France, with an area of and a population of 2,206,488.
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Pasteur Institute
The Pasteur Institute (Institut Pasteur) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines.
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Phenindamine
Phenindamine (Nolahist, Thephorin) is an antihistamine and anticholinergic closely related to cyproheptadine.
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Pheniramine
Pheniramine (INN, trade name Avil, among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.
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Phenothiazine
Phenothiazine, abbreviated PTZ, is an organic compound that has the formula S(C6H4)2NH and is related to the thiazine-class of heterocyclic compounds.
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Phenyltoloxamine
Phenyltoloxamine is an antihistamine with sedative and analgesic effects.
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Piperoxan
Piperoxan, also known as benodaine, is a drug which was the very first antihistamine to be discovered.
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Promethazine
Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family.
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Psychoactive drug
A psychoactive drug, psychopharmaceutical, or psychotropic is a chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior.
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Psychosis
Psychosis is an abnormal condition of the mind that results in difficulties telling what is real and what is not.
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Quifenadine
Quifenadine (хифенадин, trade name: Phencarol, Фенкарол) is a 2nd generation antihistamine drug, marketed mainly in post-Soviet countries.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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Rhinitis
Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose.
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Rhinorrhea
Rhinorrhea or rhinorrhoea is a condition where the nasal cavity is filled with a significant amount of mucus fluid.
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Rupatadine
Rupatadine is a second generation antihistamine and PAF antagonist used to treat allergies.
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Skin
Skin is the soft outer tissue covering vertebrates.
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Substituted piperazine
Substituted piperazines are a class of chemical compounds.
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Terfenadine
Terfenadine is an antihistamine formerly used for the treatment of allergic conditions.
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Tetracyclic antidepressant
Tetracyclic antidepressants (TeCAs) are a class of antidepressants that were first introduced starting in the 1970s.
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Thenyldiamine
Thenyldiamine is an antihistamine and anticholinergic.
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Thonzylamine
Thonzylamine (or neohetramine) is an antihistamine and anticholinergic used as an antipruritic.
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Tinnitus
Tinnitus is the hearing of sound when no external sound is present.
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Tricyclic
Tricyclics are chemical compounds that contain three interconnected rings of atoms.
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Tricyclic antidepressant
Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants.
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Tripelennamine
Tripelennamine, sold under the brand name Pyribenzamine by Novartis, is a drug that is used as an antipruritic and first-generation antihistamine.
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Triprolidine
Triprolidine is an over-the-counter antihistamine with anticholinergic properties.
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United States
The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.
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Vascular permeability
Vascular permeability, often in the form of capillary permeability or microvascular permeability, characterizes the capacity of a blood vessel wall to allow for the flow of small molecules (drugs, nutrients, water, ions) or even whole cells (lymphocytes on their way to the site of inflammation) in and out of the vessel.
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Vasodilation
Vasodilation is the widening of blood vessels.
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Weight gain
Weight gain is an increase in body weight.
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Zwitterion
In chemistry, a zwitterion, formerly called a dipolar ion, is a molecule with two or more functional groups, of which at least one has a positive and one has a negative electrical charge and the net charge of the entire molecule is zero.
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5-HT receptor
5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems.
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8-Chlorotheophylline
8-Chlorotheophylline, also known as 1,3-dimethyl-8-chloroxanthine, is a stimulant drug of the xanthine chemical class, with physiological effects similar to caffeine.
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1st generation antihistamine, 1st-generation antihistamine, 2nd generation antihistamine, 2nd-generation antihistamine, 3rd generation antihistamine, 3rd-generation antihistamine, Atypical antihistamine, Classical antihistamine, First generation antihistamine, First-generation antihistamine, H1 antagonists, H1 antihistamine, H1 antihistamines, H1 blocker, H1-receptor antagonist, H1-receptor antagonists, Histamine H1 antagonist, Histamine h1 antagonists, Second generation antihistamine, Second-generation antihistamine, Third generation antihistamine, Third-generation antihistamine, Typical antihistamine.
References
[1] https://en.wikipedia.org/wiki/H1_antagonist
