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Indeloxazine

Index Indeloxazine

Indeloxazine (INN) (Elen, Noin) is an antidepressant and cerebral activator that was marketed in Japan and South Korea by Yamanouchi Pharmaceutical Co., Ltd for the treatment of psychiatric symptoms associated with cerebrovascular diseases, namely depression resulting from stroke, emotional disturbance, and avolition. [1]

22 relations: Acetylcholine, Anticonvulsant, Antidepressant, Astellas Pharma, Avolition, Cerebral activator, Cerebrovascular disease, Depression (mood), Emotional dysregulation, Forebrain, International nonproprietary name, Japan, Mental disorder, Model organism, Neuroprotection, NMDA receptor antagonist, Nootropic, Norepinephrine reuptake inhibitor, Serotonin releasing agent, South Korea, Stroke, 5-HT4 receptor.

Acetylcholine

Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals, including humans, as a neurotransmitter—a chemical message released by nerve cells to send signals to other cells.

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Anticonvulsant

Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.

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Antidepressant

Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.

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Astellas Pharma

is a Japanese pharmaceutical company, formed on 1 April 2005 from the merger of and.

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Avolition

Avolition, as a symptom of various forms of psychopathology, is the decrease in the motivation to initiate and perform self-directed purposeful activities.

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Cerebral activator

A cerebral activator, or cerebral metabolic enhancer, is a type of drug that "activates" the central nervous system in the context of cerebrovascular diseases such as stroke and dementia.

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Cerebrovascular disease

Cerebrovascular disease includes a variety of medical conditions that affect the blood vessels of the brain and the cerebral circulation.

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Depression (mood)

Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, tendencies, feelings, and sense of well-being.

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Emotional dysregulation

Emotional dysregulation (ED) is a term used in the mental health community to refer to an emotional response that is poorly modulated, and does not fall within the conventionally accepted range of emotive response.

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Forebrain

In the anatomy of the brain of vertebrates, the forebrain or prosencephalon is the rostral-most (forward-most) portion of the brain.

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International nonproprietary name

The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.

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Japan

Japan (日本; Nippon or Nihon; formally 日本国 or Nihon-koku, lit. "State of Japan") is a sovereign island country in East Asia.

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Mental disorder

A mental disorder, also called a mental illness or psychiatric disorder, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning.

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Model organism

A model organism is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the organism model will provide insight into the workings of other organisms.

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Neuroprotection

Neuroprotection refers to the relative preservation of neuronal structure and/or function.

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NMDA receptor antagonist

NMDA receptor antagonists are a class of anesthetics that work to antagonize, or inhibit the action of, the ''N''-Methyl-D-aspartate receptor (NMDAR).

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Nootropic

Nootropics, also known as smart drugs and cognitive enhancers, are drugs, supplements, and other substances that purport to improve cognitive function, particularly executive functions, memory, creativity, or motivation, in healthy individuals.

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Norepinephrine reuptake inhibitor

A norepinephrine reuptake inhibitor (NRI, NERI) or adrenergic reuptake inhibitor (ARI), is a type of drug that acts as a reuptake inhibitor for the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline) by blocking the action of the norepinephrine transporter (NET).

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Serotonin releasing agent

A serotonin releasing agent (SRA) is a type of drug that induces the release of serotonin into the neuronal synaptic cleft.

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South Korea

South Korea, officially the Republic of Korea (대한민국; Hanja: 大韓民國; Daehan Minguk,; lit. "The Great Country of the Han People"), is a country in East Asia, constituting the southern part of the Korean Peninsula and lying east to the Asian mainland.

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Stroke

A stroke is a medical condition in which poor blood flow to the brain results in cell death.

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5-HT4 receptor

5-Hydroxytryptamine receptor 4 is a protein that in humans is encoded by the HTR4 gene.

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References

[1] https://en.wikipedia.org/wiki/Indeloxazine

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