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Innate immune system

Index Innate immune system

The innate immune system, also known as the non-specific immune system or in-born immunity system, is an important subsystem of the overall immune system that comprises the cells and mechanisms involved in the defense of the host from infection by other organisms. [1]

207 relations: Active transport, Acute (medicine), Acute-phase protein, Adaptive immune system, Allergy, Anaphylaxis, Animal, Antigen presentation, Antimicrobial, Antimicrobial peptides, Apoptosis, Arthralgia, Arthropod, Asthma, Bacillus anthracis, Bacteria, Bacteriophage, Bacteroides, Basophil, Beta-Lysine, Bile acid, Biochemical cascade, Biofilm, Bird, Blood vessel, Blood–brain barrier, Bradykinin, Burkholderia cenocepacia, Candida (fungus), Capillary, Caspase, CD1D, Cecropin, Cell membrane, Cell nucleus, Chemical messenger, Chemokine, Chemotaxis, Cholinergic anti-inflammatory pathway, CHRNA7, Coagulation, Coelom, Common cold, Complement system, Conserved sequence, Cough, Crab, CRC Press, Cryptococcus, Cysteine protease, ..., Cystic fibrosis, Cytokine, Cytolysis, Defensin, Dendrite, Dendritic cell, Desquamation, Diffusion, Digestive enzyme, DNA, Dorland's medical reference works, Elicitor, Endothelium, Entamoeba histolytica, Enzyme, Eosinophil, Erythema, Fever, Fish, Fungus, Gastric acid, Gastrointestinal tract, Giardia lamblia, Gram-positive bacteria, Granulocyte, Gut flora, Hematopoietic stem cell, Hemolymph, Heparin, Hepatocyte, Herbivore, Histamine, Histiocyte, Histoplasma, HMGB1, Human eye, Human nose, Human skin, Hydrogen peroxide, Hypersensitive response, Hypochlorite, Immune complex, Immune system, Immunity (medical), Inflammation, Inflammatory reflex, Influenza, Influenza A virus, Innate lymphoid cell, Insect, Interferon, Interleukin-1 family, Invertebrate, Jasmonic acid, Kupffer cell, Lactoferrin, Langerhans cell, Legionella, Leishmania, Leukotriene, Lipopolysaccharide, Listeria monocytogenes, Liver, Lung, Lysis, Lysosome, Lysozyme, Macrophage, Major histocompatibility complex, Mast cell, Measles, Metabolism, Methyl jasmonate, Methylation, Monocyte, Mucus, Multicellular organism, Mumps, Mutualism (biology), Myalgia, Mycobacterium, Mycobacterium tuberculosis, Natural killer cell, Natural killer T cell, Neisseria, Neoplasm, Nervous system, Neuron, Neutrophil, NK-92, Nociceptor, NOD-like receptor, Non-peptidic antigen, Opportunistic infection, Opsonin, Osmosis, Oxidizing agent, P-glycoprotein, Parasitism, Pathogen, Pathogen-associated molecular pattern, Pattern recognition receptor, Peristalsis, Peritoneal cavity, Phagocyte, Phagocytosis, Phagosome, Pharynx, Plant, Plant defense against herbivory, Plant pathology, Plasmodium malariae, Programmed cell death, Prokaryote, Prophenoloxidase, Prostaglandin, Proteolysis, Protozoa, Pseudomonas aeruginosa, Pulmonary surfactant, Pyroptosis, R gene, Reactive oxygen species, Respiratory burst, Respiratory tract, Restriction enzyme, Restriction modification system, Rheumatoid arthritis, Rhinorrhea, Rhinovirus, Rickettsia, RNA, RNA interference, Salicylic acid, Salmonella, Salmonella enterica subsp. enterica, Serotonin, Skin, Sore throat, Staphylococcus, Staphylococcus aureus, Stomach, Streptococcus, Streptococcus pyogenes, Systemic acquired resistance, T-cell receptor, Thiocyanate, Toll-like receptor, Toxicity, Transferrin, Transglutaminase, Tumor necrosis factor superfamily, V(D)J recombination, Vasodilation, Virus, White blood cell, Worm. Expand index (157 more) »

Active transport

Active transport is the movement of molecules across a membrane from a region of their lower concentration to a region of their higher concentration—in the direction against the concentration gradient.

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Acute (medicine)

In medicine, describing a disease as acute denotes that it is of short duration and, as a corollary of that, of recent onset.

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Acute-phase protein

Acute-phase proteins (APPs) are a class of proteins whose plasma concentrations increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation.

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Adaptive immune system

The adaptive immune system, also known as the acquired immune system or, more rarely, as the specific immune system, is a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate pathogens or prevent their growth.

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Allergy

Allergies, also known as allergic diseases, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.

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Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

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Animal

Animals are multicellular eukaryotic organisms that form the biological kingdom Animalia.

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Antigen presentation

Antigen presentation describes a vital immune process which is essential for T cell immune response triggering.

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Antimicrobial

An antimicrobial is an agent that kills microorganisms or stops their growth.

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Antimicrobial peptides

Antimicrobial peptides (AMPs), also called host defense peptides (HDPs) are part of the innate immune response found among all classes of life.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Arthralgia

Arthralgia (from Greek arthro-, joint + -algos, pain) literally means joint pain; it is a symptom of injury, infection, illnesses (in particular arthritis) or an allergic reaction to medication.

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Arthropod

An arthropod (from Greek ἄρθρον arthron, "joint" and πούς pous, "foot") is an invertebrate animal having an exoskeleton (external skeleton), a segmented body, and paired jointed appendages.

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Asthma

Asthma is a common long-term inflammatory disease of the airways of the lungs.

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Bacillus anthracis

Bacillus anthracis is the etiologic agent of anthrax—a common disease of livestock and, occasionally, of humans—and the only obligate pathogen within the genus Bacillus.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Bacteriophage

A bacteriophage, also known informally as a phage, is a virus that infects and replicates within Bacteria and Archaea.

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Bacteroides

Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria.

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Basophil

Basophils are a type of white blood cells.

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Beta-Lysine

β-Lysine (3,6-diaminohexanoic acid) is an amino acid produced by platelets during coagulation and is directly antibacterial by causing lysis of many Gram positive bacteria by acting as a cationic detergent.

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Bile acid

Bile acids are steroid acids found predominantly in the bile of mammals and other vertebrates.

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Biochemical cascade

A biochemical cascade, also known as a signaling cascade or signaling pathway, is a series of chemical reactions which are initiated by a stimulus (first messenger) acting on a receptor that is transduced to the cell interior through second messengers (which amplify the initial signal) and ultimately to effector molecules, resulting in a cell response to the initial stimulus.

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Biofilm

A biofilm comprises any group of microorganisms in which cells stick to each other and often also to a surface.

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Bird

Birds, also known as Aves, are a group of endothermic vertebrates, characterised by feathers, toothless beaked jaws, the laying of hard-shelled eggs, a high metabolic rate, a four-chambered heart, and a strong yet lightweight skeleton.

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Blood vessel

The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.

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Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).

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Bradykinin

Bradykinin is an inflammatory mediator.

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Burkholderia cenocepacia

Burkholderia cenocepacia, also known as Helycobacter, is a species of Gram-negative bacteria that is common in the environment, can form a biofilm with itself, is resistant to many antibiotics and may cause disease in plants.

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Candida (fungus)

Candida is a genus of yeasts and is the most common cause of fungal infections worldwide.

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Capillary

A capillary is a small blood vessel from 5 to 10 micrometres (µm) in diameter, and having a wall one endothelial cell thick.

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Caspase

Caspases (cysteine-aspartic proteases, cysteine aspartases or cysteine-dependent aspartate-directed proteases) are a family of protease enzymes playing essential roles in programmed cell death (including apoptosis, pyroptosis and necroptosis) and inflammation.

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CD1D

CD1D is the human gene that encodes the protein CD1d, a member of the CD1 (cluster of differentiation 1) family of glycoproteins expressed on the surface of various human antigen-presenting cells.

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Cecropin

Cecropins are antimicrobial peptides.

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Cell nucleus

In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.

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Chemical messenger

A chemical messenger is any compound that serves to transmit a message.

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Chemokine

Chemokines (Greek -kinos, movement) are a family of small cytokines, or signaling proteins secreted by cells.

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Chemotaxis

Chemotaxis (from chemo- + taxis) is the movement of an organism in response to a chemical stimulus.

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Cholinergic anti-inflammatory pathway

The cholinergic anti-inflammatory pathway regulates the innate immune response to injury, pathogens, and tissue ischemia.

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CHRNA7

Neuronal acetylcholine receptor subunit alpha-7, also known as nAChRα7, is a protein that in humans is encoded by the CHRNA7 gene.

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Coagulation

Coagulation (also known as clotting) is the process by which blood changes from a liquid to a gel, forming a blood clot.

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Coelom

The coelom is the main body cavity in most animals and is positioned inside the body to surround and contain the digestive tract and other organs.

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Common cold

The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory tract that primarily affects the nose.

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Complement system

The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.

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Conserved sequence

In evolutionary biology, conserved sequences are similar or identical sequences in nucleic acids (DNA and RNA) or proteins across species (orthologous sequences) or within a genome (paralogous sequences).

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Cough

A cough is a sudden and often repetitively occurring, protective reflex, which helps to clear the large breathing passages from fluids, irritants, foreign particles and microbes.

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Crab

Crabs are decapod crustaceans of the infraorder Brachyura, which typically have a very short projecting "tail" (abdomen) (translit.

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CRC Press

The CRC Press, LLC is a publishing group based in the United States that specializes in producing technical books.

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Cryptococcus

Cryptococcus (Greek for "hidden sphere") is a genus of fungi, which grow in culture as yeasts.

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Cysteine protease

Cysteine proteases, also known as thiol proteases, are enzymes that degrade proteins.

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Cystic fibrosis

Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.

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Cytokine

Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.

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Cytolysis

Cytolysis, or osmotic lysis, occurs when a cell bursts due to an osmotic imbalance that has caused excess water to diffuse into the cell.

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Defensin

Defensins are small cysteine-rich cationic proteins found in both vertebrates and invertebrates.

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Dendrite

Dendrites (from Greek δένδρον déndron, "tree"), also dendrons, are branched protoplasmic extensions of a nerve cell that propagate the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project.

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Dendritic cell

Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.

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Desquamation

Desquamation, also called skin peeling, is the shedding of the outermost membrane or layer of a tissue, such as the skin.

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Diffusion

Diffusion is the net movement of molecules or atoms from a region of high concentration (or high chemical potential) to a region of low concentration (or low chemical potential) as a result of random motion of the molecules or atoms.

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Digestive enzyme

Digestive enzymes are a group of enzymes that break down polymeric macromolecules into their smaller building blocks, in order to facilitate their absorption by the body.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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Dorland's medical reference works

Dorland's is the brand name of a family of medical reference works (including dictionaries, spellers and word books, and spell-check software) in various media spanning printed books, CD-ROMs, and online content.

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Elicitor

Elicitors in plant biology are extrinsic or foreign molecules often associated with plant pests, diseases or synergistic organisms.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Entamoeba histolytica

Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Eosinophil

Eosinophils sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply. These cells are eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes: Normally transparent, it is this affinity that causes them to appear brick-red after staining with eosin, a red dye, using the Romanowsky method. The staining is concentrated in small granules within the cellular cytoplasm, which contain many chemical mediators, such as eosinophil peroxidase, ribonuclease (RNase), deoxyribonucleases (DNase), lipase, plasminogen, and major basic protein. These mediators are released by a process called degranulation following activation of the eosinophil, and are toxic to both parasite and host tissues. In normal individuals, eosinophils make up about 1–3% of white blood cells, and are about 12–17 micrometres in size with bilobed nuclei. While they are released into the bloodstream as neutrophils are, eosinophils reside in tissue They are found in the medulla and the junction between the cortex and medulla of the thymus, and, in the lower gastrointestinal tract, ovary, uterus, spleen, and lymph nodes, but not in the lung, skin, esophagus, or some other internal organs under normal conditions. The presence of eosinophils in these latter organs is associated with disease. For instance, patients with eosinophilic asthma have high levels of eosinophils that lead to inflammation and tissue damage, making it more difficult for patients to breathe. Eosinophils persist in the circulation for 8–12 hours, and can survive in tissue for an additional 8–12 days in the absence of stimulation. Pioneering work in the 1980s elucidated that eosinophils were unique granulocytes, having the capacity to survive for extended periods of time after their maturation as demonstrated by ex-vivo culture experiments.

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Erythema

Erythema (from the Greek erythros, meaning red) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries.

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Fever

Fever, also known as pyrexia and febrile response, is defined as having a temperature above the normal range due to an increase in the body's temperature set-point.

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Fish

Fish are gill-bearing aquatic craniate animals that lack limbs with digits.

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Fungus

A fungus (plural: fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.

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Gastric acid

Gastric acid, gastric juice or stomach acid, is a digestive fluid formed in the stomach and is composed of hydrochloric acid (HCl), potassium chloride (KCl) and sodium chloride (NaCl).

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Gastrointestinal tract

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

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Giardia lamblia

Giardia lamblia, also known as Giardia intestinalis, is a flagellated parasite that colonizes and reproduces in the small intestine, causing giardiasis.

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Gram-positive bacteria

Gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their cell wall.

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Granulocyte

Granulocytes are a category of white blood cells characterized by the presence of granules in their cytoplasm.

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Gut flora

Gut flora, or gut microbiota, or gastrointestinal microbiota, is the complex community of microorganisms that live in the digestive tracts of humans and other animals, including insects.

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Hematopoietic stem cell

Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells.

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Hemolymph

Hemolymph, or haemolymph, is a fluid, analogous to the blood in vertebrates, that circulates in the interior of the arthropod body remaining in direct contact with the animal's tissues.

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Heparin

Heparin, also known as unfractionated heparin (UFH), is medication which is used as an anticoagulant (blood thinner).

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Hepatocyte

A hepatocyte is a cell of the main parenchymal tissue of the liver.

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Herbivore

A herbivore is an animal anatomically and physiologically adapted to eating plant material, for example foliage, for the main component of its diet.

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Histamine

Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.

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Histiocyte

A histiocyte is an animal cell that is part of the mononuclear phagocyte system (also known as the reticuloendothelial system or lymphoreticular system).

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Histoplasma

Histoplasma is a genus of dimorphic fungi commonly found in bird and bat fecal material.

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HMGB1

High mobility group box 1 protein, also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a protein that in humans is encoded by the HMGB1 gene.

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Human eye

The human eye is an organ which reacts to light and pressure.

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Human nose

The human nose is the protruding part of the face that bears the nostrils.

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Human skin

The human skin is the outer covering of the body.

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Hydrogen peroxide

Hydrogen peroxide is a chemical compound with the formula.

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Hypersensitive response

The hypersensitive response (HR) is a mechanism, used by plants, to prevent the spread of infection by microbial pathogens.

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Hypochlorite

In chemistry, hypochlorite is an ion with the chemical formula ClO−.

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Immune complex

An immune complex, sometimes called an antigen-antibody complex, is a molecule formed from the integral binding of an antibody to a soluble antigen.

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Immune system

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.

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Immunity (medical)

In biology, immunity is the balanced state of multicellular organisms having adequate biological defenses to fight infection, disease, or other unwanted biological invasion, while having adequate tolerance to avoid allergy, and autoimmune diseases.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Inflammatory reflex

The inflammatory reflex is a neural circuit that regulates the immune response to injury and invasion.

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Influenza

Influenza, commonly known as "the flu", is an infectious disease caused by an influenza virus.

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Influenza A virus

Influenza A virus causes influenza in birds and some mammals, and is the only species of influenza virus A genus of the Orthomyxoviridae family of viruses.

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Innate lymphoid cell

Innate lymphoid cells (ILCs) are a group of innate immune cells that are derived from common lymphoid progenitor (CLP) and belong to the lymphoid lineage.

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Insect

Insects or Insecta (from Latin insectum) are hexapod invertebrates and the largest group within the arthropod phylum.

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Interferon

Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several pathogens, such as viruses, bacteria, parasites, and also tumor cells.

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Interleukin-1 family

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines that plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults.

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Invertebrate

Invertebrates are animals that neither possess nor develop a vertebral column (commonly known as a backbone or spine), derived from the notochord.

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Jasmonic acid

Jasmonic acid (JA) is an organic compound found in several plants including jasmine.

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Kupffer cell

Kupffer cells, also known as stellate macrophages and Kupffer-Browicz cells, are specialized macrophages located in the liver, lining the walls of the sinusoids.

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Lactoferrin

Lactoferrin (LF), also known as lactotransferrin (LTF), is a multifunctional protein of the transferrin family.

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Langerhans cell

Langerhans cells are dendritic cells (antigen-presenting immune cells) of the skin, and contain organelles called Birbeck granules.

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Legionella

The genus Legionella is a pathogenic group of Gram-negative bacteria that includes the species L. pneumophila, causing legionellosis (all illnesses caused by Legionella) including a pneumonia-type illness called Legionnaires' disease and a mild flu-like illness called Pontiac fever.

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Leishmania

Leishmania is a genus of trypanosomes that are responsible for the disease leishmaniasis.

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Leukotriene

Leukotrienes are a family of eicosanoid inflammatory mediators produced in leukocytes by the oxidation of arachidonic acid (AA) and the essential fatty acid eicosapentaenoic acid (EPA) by the enzyme arachidonate 5-lipoxygenase.

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Lipopolysaccharide

Lipopolysaccharides (LPS), also known as lipoglycans and endotoxins, are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria.

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Listeria monocytogenes

Listeria monocytogenes is the species of pathogenic bacteria that causes the infection listeriosis.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Lung

The lungs are the primary organs of the respiratory system in humans and many other animals including a few fish and some snails.

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Lysis

Lysis (Greek λύσις lýsis, "a loosing" from λύειν lýein, "to unbind") refers to the breaking down of the membrane of a cell, often by viral, enzymic, or osmotic (that is, "lytic") mechanisms that compromise its integrity.

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Lysosome

A lysosome is a membrane-bound organelle found in nearly all animal cells.

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Lysozyme

Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase is an antimicrobial enzyme produced by animals that forms part of the innate immune system.

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Macrophage

Macrophages (big eaters, from Greek μακρός (makrós).

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Major histocompatibility complex

The major histocompatibility complex (MHC) is a set of cell surface proteins essential for the acquired immune system to recognize foreign molecules in vertebrates, which in turn determines histocompatibility.

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Mast cell

A mast cell (also known as a mastocyte or a labrocyte) is a type of white blood cell.

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Measles

Measles is a highly contagious infectious disease caused by the measles virus.

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Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

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Methyl jasmonate

No description.

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Methylation

In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group.

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Monocyte

Monocytes are a type of leukocyte, or white blood cell.

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Mucus

Mucus is a slippery aqueous secretion produced by, and covering, mucous membranes.

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Multicellular organism

Multicellular organisms are organisms that consist of more than one cell, in contrast to unicellular organisms.

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Mumps

Mumps is a viral disease caused by the mumps virus.

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Mutualism (biology)

Mutualism or interspecific cooperation is the way two organisms of different species exist in a relationship in which each individual benefits from the activity of the other.

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Myalgia

Myalgia, or muscle pain, is a symptom of many diseases and disorders.

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Mycobacterium

Mycobacterium is a genus of Actinobacteria, given its own family, the Mycobacteriaceae.

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Mycobacterium tuberculosis

Mycobacterium tuberculosis is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis.

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Natural killer cell

Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.

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Natural killer T cell

Natural killer T (NKT) cells are a heterogeneous group of T cells that share properties of both T cells and natural killer cells.

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Neisseria

Neisseria is a large genus of bacteria that colonize the mucosal surfaces of many animals.

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Neoplasm

Neoplasia is a type of abnormal and excessive growth of tissue.

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Nervous system

The nervous system is the part of an animal that coordinates its actions by transmitting signals to and from different parts of its body.

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Neuron

A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.

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Neutrophil

Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.

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NK-92

NK-92 is a continuously growing cell line that has features and characteristics of natural killer (NK) cells that every person has circulating in the blood.

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Nociceptor

A nociceptor is a sensory neuron that responds to damaging or potentially damaging stimuli by sending “possible threat” signals to the spinal cord and the brain.

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NOD-like receptor

The nucleotide-binding oligomerization domain-like receptors, in short NOD-like receptors (NLRs), are intracellular sensors of PAMPs that enter the cell via phagocytosis or pores and DAMPs that are associated with cell stress.

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Non-peptidic antigen

Non-peptidic antigens are low-molecular-weight compounds that stimulate human Vγ9/Vδ2 T cells.

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Opportunistic infection

An opportunistic infection is an infection caused by pathogens (bacteria, viruses, fungi, or protozoa) that take advantage of an opportunity not normally available, such as a host with a weakened immune system, an altered microbiota (such as a disrupted gut microbiota), or breached integumentary barriers.

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Opsonin

An opsonin (from the Greek opsōneîn, to prepare for eating) is any molecule that enhances phagocytosis by marking an antigen for an immune response or marking dead cells for recycling (i.e., causes the phagocyte to "relish" the marked cell).

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Osmosis

Osmosis is the spontaneous net movement of solvent molecules through a selectively permeable membrane into a region of higher solute concentration, in the direction that tends to equalize the solute concentrations on the two sides.

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Oxidizing agent

In chemistry, an oxidizing agent (oxidant, oxidizer) is a substance that has the ability to oxidize other substances — in other words to cause them to lose electrons.

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P-glycoprotein

P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) or cluster of differentiation 243 (CD243) is an important protein of the cell membrane that pumps many foreign substances out of cells.

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Parasitism

In evolutionary biology, parasitism is a relationship between species, where one organism, the parasite, lives on or in another organism, the host, causing it some harm, and is adapted structurally to this way of life.

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Pathogen

In biology, a pathogen (πάθος pathos "suffering, passion" and -γενής -genēs "producer of") or a '''germ''' in the oldest and broadest sense is anything that can produce disease; the term came into use in the 1880s.

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Pathogen-associated molecular pattern

Pathogen-associated molecular patterns, or PAMPs, are molecules associated with groups of pathogens, that are recognized by cells of the innate immune system.

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Pattern recognition receptor

Pattern recognition receptors (PRRs) play a crucial role in the proper function of the innate immune system.

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Peristalsis

Peristalsis is a radially symmetrical contraction and relaxation of muscles that propagates in a wave down a tube, in an anterograde direction.

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Peritoneal cavity

The peritoneal cavity is a potential space between the parietal peritoneum (the peritoneum that surrounds the abdominal wall) and visceral peritoneum (the peritoneum that surrounds the internal organs).

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Phagocyte

Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells.

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Phagocytosis

In cell biology, phagocytosis is the process by which a cell—often a phagocyte or a protist—engulfs a solid particle to form an internal compartment known as a phagosome.

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Phagosome

In cell biology, a phagosome is a vesicle formed around a particle engulfed by a phagocyte via phagocytosis.

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Pharynx

The pharynx (plural: pharynges) is the part of the throat that is behind the mouth and nasal cavity and above the esophagus and the larynx, or the tubes going down to the stomach and the lungs.

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Plant

Plants are mainly multicellular, predominantly photosynthetic eukaryotes of the kingdom Plantae.

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Plant defense against herbivory

Plant defense against herbivory or host-plant resistance (HPR) describes a range of adaptations evolved by plants which improve their survival and reproduction by reducing the impact of herbivores.

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Plant pathology

Plant pathology (also phytopathology) is the scientific study of diseases in plants caused by pathogens (infectious organisms) and environmental conditions (physiological factors).

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Plasmodium malariae

Plasmodium malariae is a parasitic protozoa that causes malaria in humans.

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Programmed cell death

Programmed cell death (or PCD) is the death of a cell in any form, mediated by an intracellular program.

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Prokaryote

A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.

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Prophenoloxidase

Prophenoloxidase (proPO) is a modified form of the complement response found in some invertebrates, including insects, crabs and worms.

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Prostaglandin

The prostaglandins (PG) are a group of physiologically active lipid compounds having diverse hormone-like effects in animals.

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Proteolysis

Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.

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Protozoa

Protozoa (also protozoan, plural protozoans) is an informal term for single-celled eukaryotes, either free-living or parasitic, which feed on organic matter such as other microorganisms or organic tissues and debris.

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Pseudomonas aeruginosa

Pseudomonas aeruginosa is a common Gram-negative, rod-shaped bacterium that can cause disease in plants and animals, including humans.

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Pulmonary surfactant

Pulmonary surfactant is a surface-active lipoprotein complex (phospholipoprotein) formed by type II alveolar cells.

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Pyroptosis

Pyroptosis is a highly inflammatory form of programmed cell death that occurs most frequently upon infection with intracellular pathogens and is likely to form part of the antimicrobial response.

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R gene

Resistance genes (R-Genes) are genes in plant genomes that convey plant disease resistance against pathogens by producing R proteins.

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Reactive oxygen species

Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen.

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Respiratory burst

Respiratory burst (sometimes called oxidative burst) is the rapid release of reactive oxygen species (superoxide radical and hydrogen peroxide) from different types of cells.

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Respiratory tract

In humans, the respiratory tract is the part of the anatomy of the respiratory system involved with the process of respiration.

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Restriction enzyme

A restriction enzyme or restriction endonuclease is an enzyme that cleaves DNA into fragments at or near specific recognition sites within the molecule known as restriction sites.

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Restriction modification system

The restriction modification system (RM system) is found in bacteria and other prokaryotic organisms, and provides a defense against foreign DNA, such as that borne by bacteriophages.

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Rheumatoid arthritis

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.

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Rhinorrhea

Rhinorrhea or rhinorrhoea is a condition where the nasal cavity is filled with a significant amount of mucus fluid.

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Rhinovirus

The rhinovirus (from the Greek ῥίς rhis "nose", ῥινός rhinos "of the nose", and the Latin vīrus) is the most common viral infectious agent in humans and is the predominant cause of the common cold.

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Rickettsia

Rickettsia is a genus of nonmotile, Gram-negative, nonspore-forming, highly pleomorphic bacteria that can be present as cocci (0.1 μm in diameter), rods (1–4 μm long), or thread-like (10 μm long).

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RNA

Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.

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RNA interference

RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation, by neutralizing targeted mRNA molecules.

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Salicylic acid

Salicylic acid (from Latin salix, willow tree) is a lipophilic monohydroxybenzoic acid, a type of phenolic acid, and a beta hydroxy acid (BHA).

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Salmonella

Salmonella is a genus of rod-shaped (bacillus) Gram-negative bacteria of the family Enterobacteriaceae.

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Salmonella enterica subsp. enterica

Salmonella enterica subsp.

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Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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Skin

Skin is the soft outer tissue covering vertebrates.

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Sore throat

Sore throat, also known as throat pain, is pain or irritation of the throat.

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Staphylococcus

Staphylococcus (from the σταφυλή, staphylē, "grape" and κόκκος, kókkos, "granule") is a genus of Gram-positive bacteria.

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Staphylococcus aureus

Staphylococcus aureus is a Gram-positive, round-shaped bacterium that is a member of the Firmicutes, and it is a member of the normal flora of the body, frequently found in the nose, respiratory tract, and on the skin.

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Stomach

The stomach (from ancient Greek στόμαχος, stomachos, stoma means mouth) is a muscular, hollow organ in the gastrointestinal tract of humans and many other animals, including several invertebrates.

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Streptococcus

Streptococcus (term coined by Viennese surgeon Albert Theodor Billroth (1829-1894) from strepto- "twisted" + Modern Latin coccus "spherical bacterium," from Greek kokkos meaning "berry") is a genus of coccus (spherical) Gram-positive bacteria belonging to the phylum Firmicutes and the order Lactobacillales (lactic acid bacteria).

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Streptococcus pyogenes

Streptococcus pyogenes is a species of Gram-positive bacteria.

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Systemic acquired resistance

The systemic acquired resistance (SAR) is a "whole-plant" resistance response that occurs following an earlier localized exposure to a pathogen.

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T-cell receptor

The T-cell receptor, or TCR, is a molecule found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules.

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Thiocyanate

Thiocyanate (also known as rhodanide) is the anion −. It is the conjugate base of thiocyanic acid.

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Toll-like receptor

Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system.

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Toxicity

Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.

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Transferrin

Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron (Fe) in biological fluids.

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Transglutaminase

A transglutaminase is an enzyme that catalyzes the formation of an isopeptide bond between a free amine group (e.g., protein- or peptide-bound lysine) and the acyl group at the end of the side chain of protein- or peptide-bound glutamine.

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Tumor necrosis factor superfamily

The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers.

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V(D)J recombination

V(D)J recombination is the unique mechanism of genetic recombination that occurs only in developing lymphocytes during the early stages of T and B cell maturation.

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Vasodilation

Vasodilation is the widening of blood vessels.

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Virus

A virus is a small infectious agent that replicates only inside the living cells of other organisms.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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Worm

Worms are many different distantly related animals that typically have a long cylindrical tube-like body and no limbs.

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Redirects here:

Cell-free immunity, Genetic immunity, Inherent immunity, Innate immune response, Innate immunity, Innate immunology, Innate responses, Native immunity, Natural immunity, Non specific immunity, Non-specific immunity, Nonspecific immunity, Passive immune system, Plant innate immunity, Skin barrier.

References

[1] https://en.wikipedia.org/wiki/Innate_immune_system

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