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Kinetoplast

Index Kinetoplast

A kinetoplast is a network of circular DNA (called kDNA) inside a large mitochondrion that contains many copies of the mitochondrial genome. [1]

49 relations: African trypanosomiasis, Ascidiacea, Basal body, Base excision repair, Biological target, Bodo saltans, Catenation, Commensalism, Crithidia fasciculata, Cytoskeleton, DAPI, DNA, DNA damage (naturally occurring), DNA ligase, DNA polymerase, DNA polymerase beta, DNA replication, DNA supercoil, Endonuclease, Excavata, Fish, Flagellum, Fluorescence, Fluorescence in situ hybridization, Genotoxicity, German language, Guide RNA, Helicase, Kinetoplastida, Mail (armour), Mitochondrial DNA, Mitochondrion, Mitosis, Parasitism, Plasmid, Primase, Reactive oxygen species, Snail, Spermatheca, Staining, Termite, Thymidine, Trypanosoma, Trypanosoma brucei, Trypanosoma cruzi, Type II topoisomerase, Umbilical cord, Uridine, Whale.

African trypanosomiasis

African trypanosomiasis, also known as sleeping sickness, is an insect-borne parasitic disease of humans and other animals.

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Ascidiacea

Ascidiacea (commonly known as the ascidians or sea squirts) is a paraphyletic class in the subphylum Tunicata of sac-like marine invertebrate filter feeders.

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Basal body

A basal body (synonymous with basal granule, kinetosome, and in older cytological literature with blepharoplast) is a protein structure found at the base of a eukaryotic undulipodium (cilium or flagellum).

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Base excision repair

In biochemistry and genetics, base excision repair (BER) is a cellular mechanism that repairs damaged DNA throughout the cell cycle.

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Biological target

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.

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Bodo saltans

Members of the species Bodo saltans, also known by the synonym Pleuromonas jaculans, are free-living nonparasitic kinetoplastid flagellated phagotrophic protozoan that feed on bacteria.

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Catenation

In chemistry, catenation is the bonding of atoms of the same element into a series, called a chain.

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Commensalism

Commensalism is a long term biological interaction (symbiosis) in which members of one species gain benefits while those of the other species are neither benefited nor harmed.

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Crithidia fasciculata

Crithidia fasciculata is a species of parasitic excavates.

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Cytoskeleton

A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).

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DAPI

DAPI, or 4′,6-diamidino-2-phenylindole, is a fluorescent stain that binds strongly to adenine–thymine rich regions in DNA.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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DNA damage (naturally occurring)

DNA damage is distinctly different from mutation, although both are types of error in DNA.

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DNA ligase

DNA ligase is a specific type of enzyme, a ligase, that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.

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DNA polymerase

DNA polymerases are enzymes that synthesize DNA molecules from deoxyribonucleotides, the building blocks of DNA.

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DNA polymerase beta

DNA polymerase, beta, also known as POLB, is an enzyme present in eukaryotes.

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DNA replication

In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.

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DNA supercoil

DNA supercoiling refers to the over- or under-winding of a DNA strand, and is an expression of the strain on that strand.

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Endonuclease

Endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain.

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Excavata

Excavata is a major supergroup of unicellular organisms belonging to the domain Eukaryota.

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Fish

Fish are gill-bearing aquatic craniate animals that lack limbs with digits.

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Flagellum

A flagellum (plural: flagella) is a lash-like appendage that protrudes from the cell body of certain bacterial and eukaryotic cells.

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Fluorescence

Fluorescence is the emission of light by a substance that has absorbed light or other electromagnetic radiation.

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Fluorescence in situ hybridization

Fluorescent in situ hybridization (FISH) is a molecular cytogenetic technique that uses fluorescent probes that bind to only those parts of the chromosome with a high degree of sequence complementarity.

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Genotoxicity

In genetics, genotoxicity describes the property of chemical agents that damages the genetic information within a cell causing mutations, which may lead to cancer.

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German language

German (Deutsch) is a West Germanic language that is mainly spoken in Central Europe.

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Guide RNA

Guide RNAs (a.k.a. gRNA) are the RNAs that guide the insertion or deletion of uridine residues into mitochondrial mRNAs in kinetoplastid protists in a process known as RNA editing.

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Helicase

Helicases are a class of enzymes vital to all living organisms.

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Kinetoplastida

Kinetoplastida (or Kinetoplastea, as a class) is a group of flagellated protists belonging to the phylum Euglenozoa, and characterised by the presence of an organelle with a large massed DNA called kinetoplast (hence the name).

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Mail (armour)

Mail or maille (also chain mail(le) or chainmail(le)) is a type of armour consisting of small metal rings linked together in a pattern to form a mesh.

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Mitochondrial DNA

Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, adenosine triphosphate (ATP).

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Mitochondrion

The mitochondrion (plural mitochondria) is a double-membrane-bound organelle found in most eukaryotic organisms.

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Mitosis

In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.

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Parasitism

In evolutionary biology, parasitism is a relationship between species, where one organism, the parasite, lives on or in another organism, the host, causing it some harm, and is adapted structurally to this way of life.

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Plasmid

A plasmid is a small DNA molecule within a cell that is physically separated from a chromosomal DNA and can replicate independently.

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Primase

DNA primase is an enzyme involved in the replication of DNA and is a type of RNA polymerase.

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Reactive oxygen species

Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen.

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Snail

Snail is a common name loosely applied to shelled gastropods.

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Spermatheca

The spermatheca (pronounced plural: spermathecae), also called receptaculum seminis (plural: receptacula seminis), is an organ of the female reproductive tract in insects, e.g. bees, some molluscs, oligochaeta worms and certain other invertebrates and vertebrates.

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Staining

Staining is an auxiliary technique used in microscopy to enhance contrast in the microscopic image.

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Termite

Termites are eusocial insects that are classified at the taxonomic rank of infraorder Isoptera, or as epifamily Termitoidae within the cockroach order Blattodea.

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Thymidine

Thymidine (deoxythymidine; other names deoxyribosylthymine, thymine deoxyriboside) is a pyrimidine deoxynucleoside.

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Trypanosoma

Trypanosoma is a genus of kinetoplastids (class Kinetoplastida), a monophyletic group of unicellular parasitic flagellate protozoa.

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Trypanosoma brucei

Trypanosoma brucei is a species of parasitic kinetoplastid belonging to the genus Trypanosoma.

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Trypanosoma cruzi

Trypanosoma cruzi is a species of parasitic euglenoids.

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Type II topoisomerase

Type II topoisomerases cut both strands of the DNA helix simultaneously in order to manage DNA tangles and supercoils.

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Umbilical cord

In placental mammals, the umbilical cord (also called the navel string, birth cord or funiculus umbilicalis) is a conduit between the developing embryo or fetus and the placenta.

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Uridine

Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, a ribofuranose) via a β-N1-glycosidic bond.

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Whale

Whales are a widely distributed and diverse group of fully aquatic placental marine mammals.

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References

[1] https://en.wikipedia.org/wiki/Kinetoplast

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