Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Androidâ„¢ device!
Download
Faster access than browser!
And Ads-free!

Lemborexant

Lemborexant (INN) (code name E-2006) is a dual antagonist of the orexin OX1 and OX2 receptors which is under development by Eisai for the treatment of insomnia. [1]

15 relations: Almorexant, Clinical trial, Eisai (company), Filorexant, Hypocretin (orexin) receptor 1, Hypocretin (orexin) receptor 2, Insomnia, International Nonproprietary Name, JNJ-42847922, MIN-202, Orexin, Orexin antagonist, Orexin receptor, SB-649,868, Suvorexant.

Almorexant

Almorexant (INN, codenamed ACT-078573) is an orexin antagonist, functioning as a competitive receptor antagonist of the OX1 and OX2 orexin receptors, which was being developed by the pharmaceutical companies Actelion and GSK for the treatment of insomnia.

New!!: Lemborexant and Almorexant · See more »

Clinical trial

Clinical trials are experiments done in clinical research.

New!!: Lemborexant and Clinical trial · See more »

Eisai (company)

is a Japanese pharmaceutical company headquartered in Tokyo, Japan.

New!!: Lemborexant and Eisai (company) · See more »

Filorexant

Filorexant (INN, USAN) (code name MK-6096) is an orexin antagonist which is or was under development by Merck for the treatment of insomnia.

New!!: Lemborexant and Filorexant · See more »

Hypocretin (orexin) receptor 1

Orexin receptor type 1 (Ox1R or OX1), also known as hypocretin receptor type 1, is a protein that in humans is encoded by the HCRTR1 gene.

New!!: Lemborexant and Hypocretin (orexin) receptor 1 · See more »

Hypocretin (orexin) receptor 2

Orexin receptor type 2 (Ox2R or OX2), also known as hypocretin receptor type 2, is a protein that in humans is encoded by the HCRTR2 gene.

New!!: Lemborexant and Hypocretin (orexin) receptor 2 · See more »

Insomnia

Insomnia, or trouble sleeping, is a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired.

New!!: Lemborexant and Insomnia · See more »

International Nonproprietary Name

An International Nonproprietary Name (INN) is an official generic and nonproprietary name given to a pharmaceutical drug or active ingredient.

New!!: Lemborexant and International Nonproprietary Name · See more »

JNJ-42847922

JNJ-42847922 is a selective antagonist of the orexin OX2 receptor which is under investigation by Janssen Research & Development for the treatment of major depressive disorder and insomnia.

New!!: Lemborexant and JNJ-42847922 · See more »

MIN-202

MIN-202 is a selective, small-molecule antagonist of the OX2 receptor which is under development by Minerva Neurosciences in association with Johnson & Johnson's Janssen Pharmaceutica for the treatment of insomnia.

New!!: Lemborexant and MIN-202 · See more »

Orexin

Orexin, also called hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite.

New!!: Lemborexant and Orexin · See more »

Orexin antagonist

An orexin antagonist is a drug that inhibits the effect of orexin by acting as a receptor antagonist of the orexin receptor.

New!!: Lemborexant and Orexin antagonist · See more »

Orexin receptor

The orexin receptor (also referred to as the hypocretin receptor) is a G-protein-coupled receptor that binds the neuropeptide orexin.

New!!: Lemborexant and Orexin receptor · See more »

SB-649,868

SB-649,868 is a dual orexin receptor antagonist in development by GlaxoSmithKline.

New!!: Lemborexant and SB-649,868 · See more »

Suvorexant

Suvorexant (INN, USAN) (trade name Belsomra) is a selective, dual orexin receptor antagonist marketed by Merck & Co. for the treatment of insomnia.

New!!: Lemborexant and Suvorexant · See more »

Redirects here:

E 2006, E-2006, E2006.

References

[1] https://en.wikipedia.org/wiki/Lemborexant

OutgoingIncoming
Hey! We are on Facebook now! »