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10 relations: Follicular cell, G protein–coupled receptor, Graves' disease, Gs alpha subunit, Integral membrane protein, Thyroglobulin, Thyroid hormones, Thyroid peroxidase, Thyroid-stimulating hormone, Triiodothyronine.
Follicular cell
Follicular cells (also called thyroid epithelial cells or thyrocytes) are cells in the thyroid gland that are responsible for the production and secretion of thyroid hormones thyroxine (T4) and triiodothyronine (T3).
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G protein–coupled receptor
G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.
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Graves' disease
Graves' disease, also known as toxic diffuse goiter, is an autoimmune disease that affects the thyroid.
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Gs alpha subunit
The Gs alpha subunit (Gαs, Gsα, or Gs protein) is a heterotrimeric G protein subunit that activates the cAMP-dependent pathway by activating adenylyl cyclase.
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Integral membrane protein
An integral membrane protein (IMP) is a type of membrane protein that is permanently attached to the biological membrane.
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Thyroglobulin
Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by the follicular cells of the thyroid and used entirely within the thyroid gland.
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Thyroid hormones
Thyroid hormones are two hormones produced and released by the thyroid gland, namely triiodothyronine (T3) and thyroxine (T4).
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Thyroid peroxidase
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase, is an enzyme expressed mainly in the thyroid where it is secreted into colloid.
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Thyroid-stimulating hormone
Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, TSH, or hTSH for human TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body.
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Triiodothyronine
Triiodothyronine, also known as T3, is a thyroid hormone.
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HTSHR-I, Htshr-i, LGR3, Lgr3, TSH receptor, TSH receptors, TSHR, TSHR (gene), Thyroid stimulating hormone receptor.
