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68 relations: ABCC4, Absorption (pharmacology), ACE inhibitor, Acute decompensated heart failure, Amiloride, Biological half-life, Bumetanide, Calcium, Carbonic anhydrase inhibitor, Cerebral edema, Chondrocalcinosis, Chronic kidney disease, Cirrhosis, Collecting duct system, Creatinine, Dehydration, Diuretic, Dizziness, Dyslipidemia, Ear, Edema, Electrolyte, Etacrynic acid, Furosemide, Gastrointestinal tract, Glomerulus, Gout, Hearing loss, Heart failure, Hypercalcaemia, Hypertension, Hyperuricemia, Hypokalemia, Hypomagnesemia, Hyponatremia, Kidney, Kidney failure, Loop of Henle, Macula densa, Magnesium, Mannitol, Medicine, Metabolic alkalosis, Na-K-Cl cotransporter, Nephrotic syndrome, Nonsteroidal anti-inflammatory drug, Organic anion transporter 1, Orthostatic hypotension, Osmotic pressure, Ototoxicity, ..., Prostaglandin, Proximal tubule, Pulmonary edema, Rash, Renal function, Renal medulla, Renin, Renin–angiotensin system, ROMK, Sodium-chloride symporter, Sulfonamide (medicine), Syncope (medicine), Thiazide, Tinnitus, Torasemide, Tubuloglomerular feedback, Urine, Vertigo. Expand index (18 more) »
ABCC4
ATP-binding cassette sub-family C member 4 (ABCC4), also known as the multidrug resistance-associated protein 4 (MRP4) or multi-specific organic anion transporter B (MOAT-B), is a protein that in humans is encoded by the ABCC4 gene.
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Absorption (pharmacology)
In pharmacology (and more specifically pharmacokinetics), absorption is the movement of a drug from the site of administration to bloodstream.
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ACE inhibitor
An angiotensin-converting-enzyme inhibitor (ACE inhibitor) is a pharmaceutical drug used primarily for the treatment of hypertension (elevated blood pressure) and congestive heart failure.
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Acute decompensated heart failure
Acute decompensated heart failure (ADHF) is a sudden worsening of the signs and symptoms of heart failure, which typically includes difficulty breathing (dyspnea), leg or feet swelling, and fatigue.
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Amiloride
Amiloride, sold under the trade name Midamor among others, is a medication typically used with other medications to treat high blood pressure or swelling due to heart failure or cirrhosis of the liver.
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Biological half-life
The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.
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Bumetanide
Bumetanide (trade names Bumex or Burinex) is a loop diuretic of the sulfamyl category, most often used to treat heart failure.
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Calcium
Calcium is a chemical element with symbol Ca and atomic number 20.
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Carbonic anhydrase inhibitor
Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase.
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Cerebral edema
Cerebral edema is excess accumulation of fluid in the intracellular or extracellular spaces of the brain.
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Chondrocalcinosis
Chondrocalcinosis is calcification in hyaline and/or fibrocartilage.
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Chronic kidney disease
Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney function over a period of months or years.
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Cirrhosis
Cirrhosis is a condition in which the liver does not function properly due to long-term damage.
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Collecting duct system
The collecting duct system of the kidney consists of a series of tubules and ducts that physically connect nephrons to a minor calyx or directly to the renal pelvis.
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Creatinine
Creatinine (or; from flesh) is a breakdown product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass).
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Dehydration
In physiology, dehydration is a deficit of total body water, with an accompanying disruption of metabolic processes.
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Diuretic
A diuretic is any substance that promotes diuresis, the increased production of urine.
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Dizziness
Dizziness is an impairment in spatial perception and stability.
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Dyslipidemia
Dyslipidemia is an abnormal amount of lipids (e.g. triglycerides, cholesterol and/or fat phospholipids) in the blood.
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Ear
The ear is the organ of hearing and, in mammals, balance.
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Edema
Edema, also spelled oedema or œdema, is an abnormal accumulation of fluid in the interstitium, located beneath the skin and in the cavities of the body, which can cause severe pain.
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Electrolyte
An electrolyte is a substance that produces an electrically conducting solution when dissolved in a polar solvent, such as water.
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Etacrynic acid
Etacrynic acid (INN) or ethacrynic acid (USAN), trade name Edecrin, is a loop diuretic used to treat high blood pressure and the swelling caused by diseases like congestive heart failure, liver failure, and kidney failure.
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Furosemide
Furosemide, sold under the brand name Lasix among others, is a medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease.
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Gastrointestinal tract
The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.
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Glomerulus
Glomerulus is a common term used in anatomy to describe globular structures of entwined vessels, fibers, or neurons.
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Gout
Gout is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint.
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Hearing loss
Hearing loss, also known as hearing impairment, is a partial or total inability to hear.
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Heart failure
Heart failure (HF), often referred to as congestive heart failure (CHF), is when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.
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Hypercalcaemia
Hypercalcaemia, also spelled hypercalcemia, is a high calcium (Ca2+) level in the blood serum.
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Hypertension
Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.
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Hyperuricemia
Hyperuricemia is an abnormally high level of uric acid in the blood.
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Hypokalemia
Hypokalemia, also spelled hypokalaemia, is a low level of potassium (K+) in the blood serum.
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Hypomagnesemia
Hypomagnesemia, also spelled hypomagnesaemia, is an electrolyte disturbance in which there is a low level of magnesium in the blood.
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Hyponatremia
Hyponatremia is a low sodium level in the blood.
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Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
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Kidney failure
Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys no longer work.
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Loop of Henle
In the kidney, the loop of Henle (or Henle's loop, Henle loop, nephron loop or its Latin counterpart ansa nephroni) is the portion of a nephron that leads from the proximal convoluted tubule to the distal convoluted tubule.
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Macula densa
In the kidney, the macula densa is an area of closely packed specialized cells lining the wall of the distal tubule, at the point where the thick ascending limb meets the distal convoluted tubule.
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Magnesium
Magnesium is a chemical element with symbol Mg and atomic number 12.
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Mannitol
Mannitol is a type of sugar alcohol which is also used as a medication.
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Medicine
Medicine is the science and practice of the diagnosis, treatment, and prevention of disease.
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Metabolic alkalosis
Metabolic alkalosis is a metabolic condition in which the pH of tissue is elevated beyond the normal range (7.35–7.45).
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Na-K-Cl cotransporter
The Na-K-Cl cotransporter (NKCC) is a protein that aids in the active transport of sodium, potassium, and chloride into cells.
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Nephrotic syndrome
Nephrotic syndrome is a collection of symptoms due to kidney damage.
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Nonsteroidal anti-inflammatory drug
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a drug class that reduce pain, decrease fever, prevent blood clots and, in higher doses, decrease inflammation.
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Organic anion transporter 1
The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene.
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Orthostatic hypotension
Orthostatic hypotension, also known as postural hypotension, occurs when a person's blood pressure falls when suddenly standing up from a lying or sitting position.
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Osmotic pressure
Osmotic pressure is the minimum pressure which needs to be applied to a solution to prevent the inward flow of its pure solvent across a semipermeable membrane.
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Ototoxicity
Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug.
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Prostaglandin
The prostaglandins (PG) are a group of physiologically active lipid compounds having diverse hormone-like effects in animals.
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Proximal tubule
The proximal tubule is the portion of the duct system of the nephron of the kidney which leads from Bowman's capsule to the loop of Henle.
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Pulmonary edema
Pulmonary edema is fluid accumulation in the tissue and air spaces of the lungs.
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Rash
A rash is a change of the human skin which affects its color, appearance, or texture.
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Renal function
Renal function, in nephrology, is an indication of the kidney's condition and its role in renal physiology.
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Renal medulla
The renal medulla is the innermost part of the kidney.
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Renin
Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin–angiotensin–aldosterone system (RAAS)—also known as the renin–angiotensin–aldosterone axis—that mediates the volume of extracellular fluid (blood plasma, lymph and interstitial fluid), and arterial vasoconstriction.
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Renin–angiotensin system
The renin–angiotensin system (RAS) or the renin–angiotensin–aldosterone system (RAAS) is a hormone system that regulates blood pressure and fluid balance.
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ROMK
The renal outer medullary potassium channel (ROMK) is an ATP-dependent potassium channel (Kir1.1) that transports potassium out of cells.
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Sodium-chloride symporter
The sodium-chloride symporter (also known as Na+-Cl− cotransporter, NCC or NCCT, or as the thiazide-sensitive Na+-Cl− cotransporter or TSC) is a cotransporter in the kidney which has the function of reabsorbing sodium and chloride ions from the tubular fluid into the cells of the distal convoluted tubule of the nephron.
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Sulfonamide (medicine)
Sulfonamide (also called sulphonamide, sulfa drugs or sulpha drugs) is the basis of several groups of drugs.
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Syncope (medicine)
Syncope, also known as fainting, is a loss of consciousness and muscle strength characterized by a fast onset, short duration, and spontaneous recovery.
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Thiazide
Thiazide is a type of molecule and a class of diuretics often used to treat hypertension (high blood pressure) and edema (such as that caused by heart failure, liver failure, or kidney failure).
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Tinnitus
Tinnitus is the hearing of sound when no external sound is present.
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Torasemide
Torasemide or torsemide is a pyridine-sulfonyl urea type loop diuretic mainly used in the management of edema associated with congestive heart failure.
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Tubuloglomerular feedback
In the physiology of the kidney, tubuloglomerular feedback (TGF) is a feedback system inside the kidneys.
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Urine
Urine is a liquid by-product of metabolism in humans and in many animals.
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Vertigo
Vertigo is a symptom where a person feels as if they or the objects around them are moving when they are not.
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References
[1] https://en.wikipedia.org/wiki/Loop_diuretic
