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Muscarinic acetylcholine receptor M1

Index Muscarinic acetylcholine receptor M1

The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by the CHRM1 gene. [1]

57 relations: Acanthamoeba, Acetylcholine, Adrenal medulla, Aggression, Amitriptyline, Atropine, Autonomic ganglion, Benzatropine, Biperiden, Bronchoconstriction, C-terminus, Carbachol, Catecholamine, Central nervous system, Cevimeline, Chlorpromazine, Cholera toxin, Clomipramine, Clozapine, Cyclic adenosine monophosphate, Dicycloverine, Diphenhydramine, Excitatory postsynaptic potential, Exocrine gland, Gastric acid, Gene, Gi alpha subunit, Gq alpha subunit, Gs alpha subunit, Hyoscyamine, Imipramine, Inositol trisphosphate, Ipratropium bromide, Mamba, Mating, Mirtazapine, Muscarine, Muscarinic acetylcholine receptor, Muscarinic toxin 7, Naegleria fowleri, Olanzapine, Olfaction, Oxotremorine, Oxybutynin, Pertussis toxin, Phospholipase, Pilocarpine, Pirenzepine, Potassium, Quetiapine, ..., Salivary gland, Stomach, Telenzepine, Tolterodine, Vedaclidine, Xanomeline, 77-LH-28-1. Expand index (7 more) »

Acanthamoeba

Acanthamoeba is a genus of amoebae, a single-celled eukaryote commonly recovered from soil, fresh water and other habitats.

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Acetylcholine

Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals, including humans, as a neurotransmitter—a chemical message released by nerve cells to send signals to other cells.

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Adrenal medulla

The adrenal medulla (medulla glandulae suprarenalis) is part of the adrenal gland.

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Aggression

Aggression is overt, often harmful, social interaction with the intention of inflicting damage or other unpleasantness upon another individual.

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Amitriptyline

Amitriptyline, sold under the brand name Elavil among others, is a medicine primarily used to treat a number of mental illnesses.

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Atropine

Atropine is a medication to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate and to decrease saliva production during surgery.

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Autonomic ganglion

An autonomic ganglion is a cluster of nerve cell bodies (a ganglion) in the autonomic nervous system.

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Benzatropine

Benzatropine, also known as benztropine, is an anticholinergic marketed under the trade name Cogentin which is used in the treatment of Parkinson's disease, Parkinsonism, and dystonia.

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Biperiden

Biperiden, sold under the brandname Akineton among others, is a medication used to treat Parkinson disease and certain drug-induced movement disorders.

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Bronchoconstriction

Bronchoconstriction is the constriction of the airways in the lungs due to the tightening of surrounding smooth muscle, with consequent coughing, wheezing, and shortness of breath.

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C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

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Carbachol

Carbachol (Carbastat, Carboptic, Isopto Carbachol, Miostat), also known as carbamylcholine, is a cholinomimetic drug that binds and activates acetylcholine receptors.

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Catecholamine

A catecholamine (CA) is a monoamine, an organic compound that has a catechol (benzene with two hydroxyl side groups at carbons 1 and 2) and a side-chain amine.

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Cevimeline

Cevimeline (trade name Evoxac) is a parasympathomimetic and muscarinic agonist, with particular effect on M1 and M3 receptors.

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Chlorpromazine

Chlorpromazine (CPZ), marketed under the trade names Thorazine and Largactil among others, is an antipsychotic medication.

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Cholera toxin

Cholera toxin (also known as choleragen and sometimes abbreviated to CTX, Ctx or CT) is protein complex secreted by the bacterium Vibrio cholerae.

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Clomipramine

Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA).

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Clozapine

Clozapine, sold under the brand name Clozaril among others, is an atypical antipsychotic medication.

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Cyclic adenosine monophosphate

Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger important in many biological processes.

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Dicycloverine

Dicycloverine, also known as dicyclomine, is a prescription medication that relieves muscle spasms in the gastrointestinal tract through an apparent mechanism of nonselective smooth muscle relaxation, and that presents a range of anticholinergic side effects.

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Diphenhydramine

Diphenhydramine is an antihistamine mainly used to treat allergies.

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Excitatory postsynaptic potential

In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential.

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Exocrine gland

Exocrine glands are glands that produce and secrete substances onto an epithelial surface by way of a duct.

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Gastric acid

Gastric acid, gastric juice or stomach acid, is a digestive fluid formed in the stomach and is composed of hydrochloric acid (HCl), potassium chloride (KCl) and sodium chloride (NaCl).

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Gi alpha subunit

Gi alpha subunit (Gαi, or Gi/G0 or Gi protein) is a heterotrimeric G protein subunit that inhibits the production of cAMP from ATP.

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Gq alpha subunit

Gq protein (Gαq, or Gq/11) is a heterotrimeric G protein subunit that activates phospholipase C (PLC).

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Gs alpha subunit

The Gs alpha subunit (Gαs, Gsα, or Gs protein) is a heterotrimeric G protein subunit that activates the cAMP-dependent pathway by activating adenylyl cyclase.

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Hyoscyamine

Hyoscyamine (also known as daturine) is a tropane alkaloid.

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Imipramine

Imipramine, sold under the brand name Tofranil among others, is a tricyclic antidepressant (TCA) which is used mainly in the treatment of depression.

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Inositol trisphosphate

Inositol trisphosphate or inositol 1,4,5-trisphosphate (also commonly known as triphosphoinositol; abbreviated InsP3 or Ins3P or IP3), together with diacylglycerol (DAG), is a secondary messenger molecule used in signal transduction and lipid signaling in biological cells.

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Ipratropium bromide

Ipratropium bromide, sold under the trade name Atrovent among others, is a medication which opens up the medium and large airways in the lungs.

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Mamba

Mambas are fast-moving venomous snakes of the genus Dendroaspis (which literally means "tree asp") in the family Elapidae.

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Mating

In biology, mating (or mateing in British English) is the pairing of either opposite-sex or hermaphroditic organisms, usually for the purposes of sexual reproduction.

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Mirtazapine

Mirtazapine, sold under the brand name Remeron among others, is an atypical antidepressant which is used primarily in the treatment of depression.

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Muscarine

Muscarine, L-(+)-muscarine, or muscarin is a natural product found in certain mushrooms, particularly in Inocybe and Clitocybe species, such as the deadly C. dealbata.

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Muscarinic acetylcholine receptor

Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain neurons and other cells.

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Muscarinic toxin 7

Muscarinic toxin 7 (MT7) is one member of a family of small peptides of 65 amino acid residues derived from the venom of African mamba snakes (Dendroaspis angusticeps), which mainly target M1-subtype of muscarinic receptor.

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Naegleria fowleri

Naegleria fowleri, colloquially known as the "brain-eating amoeba", is a species of the genus Naegleria, belonging to the phylum Percolozoa.

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Olanzapine

Olanzapine (originally branded Zyprexa) is an antipsychotic medication used to treat schizophrenia and bipolar disorder.

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Olfaction

Olfaction is a chemoreception that forms the sense of smell.

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Oxotremorine

Oxotremorine (i.e. oxo M) is a parasympathomimetic drug that acts as a selective muscarinic acetylcholine receptor agonist.

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Oxybutynin

Oxybutynin (brand names Ditropan, Lyrinel XL, Lenditro (ZA), Driptane (RU), Uripan (Middle East)) is an anticholinergic medication used to relieve urinary and bladder difficulties, including frequent urination and inability to control urination (urge incontinence), by decreasing muscle spasms of the bladder.

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Pertussis toxin

Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough.

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Phospholipase

A phospholipase is an enzyme that hydrolyzes phospholipids into fatty acids and other lipophilic substances.

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Pilocarpine

Pilocarpine is a medication used to treat increased pressure inside the eye and dry mouth.

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Pirenzepine

Pirenzepine (Gastrozepin), an M1 selective antagonist, is used in the treatment of peptic ulcers, as it reduces gastric acid secretion and reduces muscle spasm.

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Potassium

Potassium is a chemical element with symbol K (from Neo-Latin kalium) and atomic number 19.

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Quetiapine

Quetiapine, marketed as Seroquel among other names, is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.

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Salivary gland

The salivary glands in mammals are exocrine glands that produce saliva through a system of ducts.

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Stomach

The stomach (from ancient Greek στόμαχος, stomachos, stoma means mouth) is a muscular, hollow organ in the gastrointestinal tract of humans and many other animals, including several invertebrates.

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Telenzepine

Telenzepine is a thienobenzodiazepine acting as selective M1 antimuscarinic.

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Tolterodine

Tolterodine (trade names Detrol, Detrusitol) is an antimuscarinic drug that is used for symptomatic treatment of urinary incontinence.

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Vedaclidine

Vedaclidine (INN, codenamed LY-297,802, NNC 11-1053) is a novel analgesic drug which acts as a mixed agonist–antagonist at muscarinic acetylcholine receptors, being a potent and selective agonist for the M1 and M4 subtypes, yet an antagonist at the M2, M3 and M5 subtypes.

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Xanomeline

Xanomeline (LY-246,708; Lumeron, Memcor) is a muscarinic acetylcholine receptor agonist with reasonable selectivity for the M1 and M4 subtypes, though it is also known to act as a M5 receptor antagonist.

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77-LH-28-1

77-LH-28-1 is a selective agonist of muscarinic acetylcholine receptor subtype 1 (M1) discovered in 2008.

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Redirects here:

CHRM1, CHRM1 (gene), M1 muscarinic receptor, M1 receptor, M1 receptors, Muscarinic acetylcholine receptor m1, Receptor, muscarinic m1.

References

[1] https://en.wikipedia.org/wiki/Muscarinic_acetylcholine_receptor_M1

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