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Trestolone

Index Trestolone

Trestolone, also known as 7α-methyl-19-nortestosterone (MENT), is an experimental androgen/anabolic steroid (AAS) and progestogen medication which has been under development for potential use as a form of hormonal birth control for men and in androgen replacement therapy for low testosterone levels in men but has never been marketed for medical use. [1]

86 relations: Agonist, Aldosterone, Anabolic steroid, Anabolism, Androgen, Androgen ester, Androgen prohormone, Androgen receptor, Androgen replacement therapy, Antigonadotropin, Aromatase, Azoospermia, Bioavailability, Biological half-life, Biological target, Bone density, Derivative (chemistry), Dihydrotestosterone, Dimethandrolone, Dimethyltrienolone, Erectile dysfunction, Estradiol (medication), Estrane, Estrogen (medication), Experimental drug, Fatigue, Follicle-stimulating hormone, Gel, Gonadotropin, Hair follicle, Hormonal contraception, Hydrocortisone, Hypoactive sexual desire disorder, Hypoestrogenism, Hypogonadism, Intramuscular injection, Libido, Ligand (biochemistry), Luteinizing hormone, Male contraceptive, Metabolite, Methyl group, Mibolerone, Nandrolone, Non-governmental organization, Nonprofit organization, Oligospermia, Oral administration, Organic compound, Osteoporosis, ..., Pharmacokinetics, Pituitary gland, Population Council, Potency (pharmacology), Prodrug, Progesterone, Progesterone (medication), Progesterone receptor, Progestin, Progestogen, Prostate, Reproductive health, Route of administration, Secondary sex characteristic, Sexual dysfunction, Side effect, Skeletal muscle, Skin, Spermatogenesis, Spermatozoon, Steroid, Subcutaneous implant, Substrate (chemistry), Symptom, Testicle, Testosterone, Testosterone (medication), Tibolone, Tissue (biology), Topical medication, Trademark distinctiveness, Transdermal patch, Trestolone acetate, 5α-Reductase, 7α-Methyl-19-norandrostenedione, 7α-Methylestradiol. Expand index (36 more) »

Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Aldosterone

Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.

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Anabolic steroid

Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.

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Anabolism

Anabolism (from ἁνά, "upward" and βάλλειν, "to throw") is the set of metabolic pathways that construct molecules from smaller units.

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Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.

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Androgen ester

An androgen or anabolic steroid ester is an ester of an androgen/anabolic steroid (AAS) such as the natural testosterone or dihydrotestosterone (DHT) or the synthetic nandrolone (19-nortestosterone).

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Androgen prohormone

An androgen prohormone, or proandrogen, is a prohormone (or prodrug) of an anabolic-androgenic steroid (AAS).

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Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

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Androgen replacement therapy

Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a class of hormone replacement therapy in which androgens, often testosterone, are replaced.

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Antigonadotropin

An antigonadotropin is a drug which suppresses the activity and/or downstream effects of one or both of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

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Aromatase

Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens.

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Azoospermia

Azoospermia is the medical condition of a man whose semen contains no sperm.

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Bioavailability

In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.

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Biological half-life

The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.

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Biological target

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.

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Bone density

Bone density, or bone mineral density (BMD), is the amount of bone mineral in bone tissue.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Dihydrotestosterone

Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.

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Dimethandrolone

Dimethandrolone (DMA), also known by its developmental code name CDB-1321, is an experimental androgen/anabolic steroid (AAS) and progestogen medication which is under investigation for potential clinical use.

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Dimethyltrienolone

Dimethyltrienolone (developmental code name RU-2420) is a synthetic, orally active, and extremely potent anabolic–androgenic steroid (AAS) and 17α-alkylated 19-nortestosterone (nandrolone) derivative which was never marketed for medical use.

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Erectile dysfunction

Erectile dysfunction (ED), also known as impotence, is a type of sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity.

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Estradiol (medication)

Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.

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Estrane

Estrane is a C18 steroid derivative, with a gonane core.

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Estrogen (medication)

An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Experimental drug

An experimental drug is a medicinal product (a drug or vaccine) that has not yet received approval from governmental regulatory authorities for routine use in human or veterinary medicine.

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Fatigue

Fatigue is a subjective feeling of tiredness that has a gradual onset.

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Follicle-stimulating hormone

Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone.

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Gel

A gel is a solid jelly-like material that can have properties ranging from soft and weak to hard and tough.

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Gonadotropin

Gonadotropins are glycoprotein polypeptide hormones secreted by gonadotrope cells of the anterior pituitary of vertebrates.

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Hair follicle

The hair follicle is a dynamic organ found in mammalian skin.

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Hormonal contraception

Hormonal contraception refers to birth control methods that act on the endocrine system.

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Hydrocortisone

Hydrocortisone, sold under a number of brand names, is the name for the hormone cortisol when supplied as a medication.

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Hypoactive sexual desire disorder

Hypoactive sexual desire disorder (HSDD) or inhibited sexual desire (ISD) is considered a sexual dysfunction and is characterized as a lack or absence of sexual fantasies and desire for sexual activity, as judged by a clinician.

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Hypoestrogenism

Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen, the primary sex hormone in women.

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Hypogonadism

Hypogonadism means diminished functional activity of the gonads—the testes or the ovaries —that may result in diminished sex hormone biosynthesis.

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Intramuscular injection

Intramuscular (also IM or im) injection is the injection of a substance directly into muscle.

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Libido

Libido, colloquially known as sex drive, is a person's overall sexual drive or desire for sexual activity.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Luteinizing hormone

Luteinizing hormone (LH, also known as lutropin and sometimes lutrophin) is a hormone produced by gonadotropic cells in the anterior pituitary gland.

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Male contraceptive

Male contraceptives, also known as male birth control are methods of preventing pregnancy that primarily involve the male physiology.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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Methyl group

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.

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Mibolerone

Mibolerone, also known as dimethylnortestosterone (DMNT) and sold under the brand names Cheque Drops and Matenon, is a synthetic, orally active, and extremely potent anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was marketed by Upjohn for use as a veterinary drug.

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Nandrolone

Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).

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Non-governmental organization

Non-governmental organizations, nongovernmental organizations, or nongovernment organizations, commonly referred to as NGOs, are usually non-profit and sometimes international organizations independent of governments and international governmental organizations (though often funded by governments) that are active in humanitarian, educational, health care, public policy, social, human rights, environmental, and other areas to effect changes according to their objectives.

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Nonprofit organization

A non-profit organization (NPO), also known as a non-business entity or non-profit institution, is dedicated to furthering a particular social cause or advocating for a shared point of view.

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Oligospermia

Terms oligospermia and oligozoospermia refer to semen with a low concentration of sperm and is a common finding in male infertility.

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Oral administration

| name.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Osteoporosis

Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone.

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Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.

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Pituitary gland

An explanation of the development of the pituitary gland (Hypophysis cerebri) & the congenital anomalies. In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland about the size of a pea and weighing in humans.

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Population Council

The Population Council is an international, nonprofit, non-governmental organization.

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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Prodrug

A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.

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Progesterone

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.

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Progesterone (medication)

Progesterone is a medication and naturally occurring steroid hormone.

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Progesterone receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.

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Progestin

A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Progestogen

Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).

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Prostate

The prostate (from Ancient Greek προστάτης, prostates, literally "one who stands before", "protector", "guardian") is a compound tubuloalveolar exocrine gland of the male reproductive system in most mammals.

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Reproductive health

Within the framework of the World Health Organization's (WHO) definition of health as a state of complete physical, mental and social well-being, and not merely the absence of disease or infirmity, reproductive health, or sexual health/hygiene, addresses the reproductive processes, functions and system at all stages of life.

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Route of administration

A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body.

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Secondary sex characteristic

Secondary sex characteristics are features that appear during puberty in humans, and at sexual maturity in other animals.

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Sexual dysfunction

Sexual dysfunction (or sexual malfunction or sexual disorder) is difficulty experienced by an individual or a couple during any stage of a normal sexual activity, including physical pleasure, desire, preference, arousal or orgasm.

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Side effect

In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.

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Skeletal muscle

Skeletal muscle is one of three major muscle types, the others being cardiac muscle and smooth muscle.

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Skin

Skin is the soft outer tissue covering vertebrates.

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Spermatogenesis

Spermatogenesis is the process by which haploid spermatozoa develop from germ cells in the seminiferous tubules of the testis.

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Spermatozoon

A spermatozoon (pronounced, alternate spelling spermatozoön; plural spermatozoa; from σπέρμα "seed" and ζῷον "living being") is a motile sperm cell, or moving form of the haploid cell that is the male gamete.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Subcutaneous implant

In medicine, a subcutaneous implant, or subcutaneous pellet, is an implant that is delivered under the skin into the subcutaneous tissue by surgery or injection and is used to deliver a drug for a long period of time.

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Substrate (chemistry)

In chemistry, a substrate is typically the chemical species being observed in a chemical reaction, which reacts with a reagent to generate a product.

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Symptom

A symptom (from Greek σύμπτωμα, "accident, misfortune, that which befalls", from συμπίπτω, "I befall", from συν- "together, with" and πίπτω, "I fall") is a departure from normal function or feeling which is noticed by a patient, reflecting the presence of an unusual state, or of a disease.

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Testicle

The testicle or testis is the male reproductive gland in all animals, including humans.

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Testosterone

Testosterone is the primary male sex hormone and an anabolic steroid.

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Testosterone (medication)

Testosterone is a medication and naturally occurring steroid hormone.

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Tibolone

Tibolone, sold under the brand names Livial and Tibofem among others, is a medication which is used in menopausal hormone therapy and in the treatment of postmenopausal osteoporosis and endometriosis.

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Tissue (biology)

In biology, tissue is a cellular organizational level between cells and a complete organ.

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Topical medication

A topical medication is a medication that is applied to a particular place on or in the body.

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Trademark distinctiveness

Trademark distinctiveness is an important concept in the law governing trademarks and service marks.

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Transdermal patch

A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream.

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Trestolone acetate

Trestolone acetate (developmental code names CDB-903, NSC-69948, U-15614; also known as 7α-methyl-19-nortestosterone 17β-acetate and 7α-methylestr-4-en-17β-ol-3-one 17β-acetate) is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed.

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5α-Reductase

5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.

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7α-Methyl-19-norandrostenedione

7α-Methyl-19-norandrostenedione (MENT dione), or 7α-methyl-19-norandrost-4-ene-3,17-dione, also known as trestione, as well as 7α-methylestr-4-ene-3,17-dione, is a synthetic anabolic-androgenic steroid (AAS) and a derivative of 19-nortestosterone (nandrolone).

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7α-Methylestradiol

7α-Methylestradiol (7α-Me-E2), also known as 7α-methylestra-1,3,5(10)-triene-3,17β-diol, is a synthetic estrogen and an active metabolite of the androgen/anabolic steroid trestolone.

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Redirects here:

7-MENT, 7MENT, 7α-Methyl-19-nortestosterone, MENT Ac, RU 27333, RU-27333, RU27333, Trestolone Ac.

References

[1] https://en.wikipedia.org/wiki/Trestolone

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