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36 relations: Alpha helix, Anterior pituitary, Antigen, Beta sheet, Biological target, BNIPL, CD44, CD74, Cell-mediated immunity, COP9 constitutive photomorphogenic homolog subunit 5, CXCR4, Cytosol, DHICA, Disulfide, Dopachrome, Extracellular signal–regulated kinases, Gene, Glucocorticoid, Inflammation, Injury, Innate immune system, Integrin, Lymphokine, Macrophage, N-terminus, Non-receptor tyrosine kinase, Phenylpyruvate tautomerase, Phosphorylation, Proinflammatory cytokine, Protein, Protein trimer, Protein–protein interaction, Reductase, Rotational symmetry, White blood cell, 40S ribosomal protein S19.
Alpha helix
The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.
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Anterior pituitary
A major organ of the endocrine system, the anterior pituitary (also called the adenohypophysis or pars anterior), is the glandular, anterior lobe that together with the posterior lobe (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis).
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Antigen
In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.
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Beta sheet
The β-sheet (also β-pleated sheet) is a common motif of regular secondary structure in proteins.
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Biological target
A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.
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BNIPL
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein is a protein that in humans is encoded by the BNIPL gene.
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CD44
The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration.
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CD74
HLA class II histocompatibility antigen gamma chain also known as HLA-DR antigens-associated invariant chain or CD74 (Cluster of Differentiation 74), is a protein that in humans is encoded by the CD74 gene.
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Cell-mediated immunity
Cell-mediated immunity is an immune response that does not involve antibodies, but rather involves the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen.
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COP9 constitutive photomorphogenic homolog subunit 5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), also known as COPS5 or Csn5, is a gene conserved from humans to Saccharomyces cerevisiae.
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CXCR4
C-X-C chemokine receptor type 4 (CXCR-4) also known as fusin or CD184 (cluster of differentiation 184) is a protein that in humans is encoded by the CXCR4 gene.
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Cytosol
The cytosol, also known as intracellular fluid (ICF) or cytoplasmic matrix, is the liquid found inside cells.
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DHICA
DHICA (5,6-dihydroxyindole-2-carboxylic acid) is an intermediate in the biosynthesis of melanin.
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Disulfide
In chemistry, a disulfide refers to a functional group with the structure R−S−S−R′.
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Dopachrome
Dopachrome is a cyclization product of L-DOPA and is an intermediate in the biosynthesis of melanin.
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Extracellular signal–regulated kinases
In molecular biology, extracellular signal–regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Glucocorticoid
Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.
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Inflammation
Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.
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Injury
Injury, also known as physical trauma, is damage to the body caused by external force.
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Innate immune system
The innate immune system, also known as the non-specific immune system or in-born immunity system, is an important subsystem of the overall immune system that comprises the cells and mechanisms involved in the defense of the host from infection by other organisms.
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Integrin
Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.
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Lymphokine
Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte.
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Macrophage
Macrophages (big eaters, from Greek μακρός (makrós).
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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Non-receptor tyrosine kinase
Non-receptor tyrosine kinases (nRTKs) are cytosolic enzymes that are responsible for catalysing the transfer of a phosphate group from a nucleoside triphosphate donor, such as ATP, to tyrosine residues in proteins.
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Phenylpyruvate tautomerase
In enzymology, phenylpyruvate tautomerase or Macrophage migration inhibitory factor is an enzyme that catalyzes the chemical reaction Phenylpyruvate tautomerase has also been found to exhibit the same keto-enol tautomerism for 4-Hydroxyphenylpyruvic acid, which is structurally similar to phenylpyruvate but contains an additional hydroxyl moiety in the para position of the aromatic ring.
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Phosphorylation
In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.
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Proinflammatory cytokine
A proinflammatory cytokine or more simply an inflammatory cytokine is a type of signaling molecule (a cytokine) that is excreted from immune cells like helper T cells (Th) and macrophages, and certain other cell types that promote inflammation.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein trimer
In biochemistry, a protein trimer is a macromolecular complex formed by three, usually non-covalently bound, macromolecules like proteins or nucleic acids.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Reductase
A reductase is an enzyme that catalyzes a reduction reaction.
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Rotational symmetry
Rotational symmetry, also known as radial symmetry in biology, is the property a shape has when it looks the same after some rotation by a partial turn.
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White blood cell
White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
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40S ribosomal protein S19
40S ribosomal protein S19 is a protein that in humans is encoded by the RPS19 gene.
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Redirects here:
MIF (gene), MMIF, Macrophage migration inhibition factor, Macrophage migration-inhibitory factors, Mmif.
References
[1] https://en.wikipedia.org/wiki/Macrophage_migration_inhibitory_factor
