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Neuraminidase

Index Neuraminidase

Neuraminidase enzymes are glycoside hydrolase enzymes that cleave the glycosidic linkages of neuraminic acids. [1]

27 relations: Bacterial neuraminidase, Enzyme, Epitope, FLAG-tag, Glycoside hydrolase, Glycosidic bond, Human genome, Influenza, Influenza A virus subtype H1N1, Laninamivir, NEU1, NEU2, NEU3, NEU4, Neuraminic acid, Neuraminidase inhibitor, Oseltamivir, Peramivir, Protein, Recombinant virus, Sialic acid, Sialidase, Staphylothermus, UniProt, Viral neuraminidase, Yeast, Zanamivir.

Bacterial neuraminidase

Bacterial neuraminidase is type of neuraminidase and a virulence factor for many bacteria including Bacteroides fragilis and Pseudomonas aeruginosa.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Epitope

An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells.

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FLAG-tag

FLAG-tag, or FLAG octapeptide, or FLAG epitope, is a polypeptide protein tag that can be added to a protein using recombinant DNA technology, having the sequence motif DYKDDDDK (where D.

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Glycoside hydrolase

Glycoside hydrolases (also called glycosidases or glycosyl hydrolases) catalyze the hydrolysis of glycosidic bonds in complex sugars.

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Glycosidic bond

In chemistry, a glycosidic bond or glycosidic linkage is a type of covalent bond that joins a carbohydrate (sugar) molecule to another group, which may or may not be another carbohydrate.

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Human genome

The human genome is the complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria.

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Influenza

Influenza, commonly known as "the flu", is an infectious disease caused by an influenza virus.

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Influenza A virus subtype H1N1

Influenza A (H1N1) virus is the subtype of influenza A virus that was the most common cause of human influenza (flu) in 2009, and is associated with the 1918 outbreak known as the Spanish Flu.

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Laninamivir

Laninamivir (CS-8958) is a neuraminidase inhibitor which is being researched for the treatment and prophylaxis of Influenzavirus A and Influenzavirus B. It is currently in Phase III clinical trials.

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NEU1

Sialidase 1 (lysosomal sialidase), also known as NEU1 is a mammalian lysosomal neuraminidase enzyme which in humans is encoded by the NEU1 gene.

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NEU2

Sialidase-2 is an enzyme that in humans is encoded by the NEU2 gene.

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NEU3

Sialidase-3 is an enzyme that in humans is encoded by the NEU3 gene.

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NEU4

Sialidase-4 is an enzyme that in humans is encoded by the NEU4 gene.

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Neuraminic acid

Neuraminic acid (5-amino-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid) is a 9-carbon monosaccharide (a nonose), a derivative of a ketononose.

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Neuraminidase inhibitor

Neuraminidase inhibitors (NAIs) are a class of drugs which block the neuraminidase enzyme.

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Oseltamivir

Oseltamivir, sold under the brand name Tamiflu, is an antiviral medication used to treat and prevent influenza A and influenza B (flu).

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Peramivir

Peramivir (trade name Rapivab) is an antiviral drug developed by BioCryst Pharmaceuticals for the treatment of influenza.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Recombinant virus

A recombinant virus is a virus produced by recombining pieces of DNA using recombinant DNA technology.

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Sialic acid

Sialic acid is a generic term for the N- or O-substituted derivatives of neuraminic acid, a monosaccharide with a nine-carbon backbone.

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Sialidase

Sialidases hydrolyse alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.

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Staphylothermus

In taxonomy, Staphylothermus is a genus of the Desulfurococcaceae.

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UniProt

UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects.

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Viral neuraminidase

Viral neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the host cell.

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Yeast

Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom.

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Zanamivir

Zanamivir is a medication used to treat and prevent influenza caused by influenza A and B viruses.

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Redirects here:

Acetylneuraminyl hydrolase, EC 3.2.1.18, Exo-a-sialidase, Neuraminadase, Neuraminidases, Nuraminidase.

References

[1] https://en.wikipedia.org/wiki/Neuraminidase

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