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105 relations: Absence seizure, Action potential, Adams–Stokes syndrome, Agranulocytosis, Allele, Antacid, Antiarrhythmic agent, Anticonvulsant, Aplastic anemia, Ataxia, Atrial tachycardia, Atrioventricular block, Atrophy, Benzodiazepine, Bone marrow suppression, Breastfeeding, Carbamazepine, Carcinogen, Cardiac glycoside, Cerebellum, Cerebral cortex, Competition and Markets Authority, CYP2C9, CYP3A4, Cytochrome P450, Developing country, Digoxin toxicity, Diplopia, Dreyfus Corporation, Epileptic seizure, Ethanol, Exudate, Fetal alcohol spectrum disorder, Fetal hydantoin syndrome, Focal seizure, Folate deficiency, Food and Drug Administration, Freiburg im Breisgau, Gamma-glutamyl hydrolase, Generalised tonic-clonic seizure, Germany, Gingival enlargement, H. Houston Merritt, Health system, Heart arrhythmia, Heinrich Biltz, Hirsutism, HLA-B, HLA-B75, Hydantoin, ..., Hypertrichosis, Hypocalcaemia, Hypophosphatemia, Hypotension, Intravenous therapy, Ireland, Itch, Jack Dreyfus, Leukopenia, Liver, Major depressive disorder, Megaloblastic anemia, Microcephaly, Multiple sclerosis, National Health Service, National Institutes of Health, Neuropathic pain, Nystagmus, Parke-Davis, Peripheral neuropathy, Pfizer, Pharmacodynamics, Phenobarbital, Post-tetanic potentiation, Potassium bromide, Pregnancy category, Purple glove syndrome, Randomized controlled trial, Richard Nixon, Sedation, Selective immunoglobulin A deficiency, Self-harm, Sinoatrial block, Sinus bradycardia, Sodium channel, Somnolence, Status epilepticus, Stevens–Johnson syndrome, Systemic lupus erythematosus, Temporal lobe, Teratology, Therapeutic index, Thrombocytopenia, Toxic epidermal necrolysis, Tracy Putnam, Trade name, Tremor, Trigeminal neuralgia, Trimethoprim, United States dollar, Ventricular tachycardia, Vitamin D, Vitamin D deficiency, Warfarin, WHO Model List of Essential Medicines. Expand index (55 more) »
Absence seizure
Absence seizures are one of several kinds of generalized seizures.
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Action potential
In physiology, an action potential occurs when the membrane potential of a specific axon location rapidly rises and falls: this depolarisation then causes adjacent locations to similarly depolarise.
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Adams–Stokes syndrome
Stokes–Adams syndrome (alternative eponyms include Adams–Stokes syndrome, Gerbezius–Morgagni–Adams–Stokes syndrome and Gerbec–Morgagni–Adams–Stokes syndrome) is a periodic fainting spell in which there is a periodic onset and offset of blockage of heart due to disorder of heart rhythm that may last for seconds, hours, days, or even weeks before the conduction returns.
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Agranulocytosis
Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous leukopenia (lowered white blood cell count), most commonly of neutrophils causing a neutropenia in the circulating blood.
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Allele
An allele is a variant form of a given gene.
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Antacid
An antacid is a substance which neutralizes stomach acidity and is used to relieve heartburn, indigestion or an upset stomach.
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Antiarrhythmic agent
Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a group of pharmaceuticals that are used to suppress abnormal rhythms of the heart (cardiac arrhythmias), such as atrial fibrillation, atrial flutter, ventricular tachycardia, and ventricular fibrillation.
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Anticonvulsant
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.
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Aplastic anemia
Aplastic anaemia is a rare disease in which the bone marrow and the hematopoietic stem cells that reside there are damaged.
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Ataxia
Ataxia is a neurological sign consisting of lack of voluntary coordination of muscle movements that includes gait abnormality.
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Atrial tachycardia
Atrial tachycardia is a type of heart rhythm problem in which the heart's electrical impulse comes from an ectopic pacemaker (that is, an abnormally located cardiac pacemaker) in the upper chambers (atria) of the heart, rather than from the sinoatrial node, the normal origin of the heart's electrical activity.
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Atrioventricular block
Atrioventricular block (AV block) is a type of heart block in which the conduction between the atria and ventricles of the heart is impaired.
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Atrophy
Atrophy is the partial or complete wasting away of a part of the body.
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Benzodiazepine
Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.
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Bone marrow suppression
Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).
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Breastfeeding
Breastfeeding, also known as nursing, is the feeding of babies and young children with milk from a woman's breast.
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Carbamazepine
Carbamazepine (CBZ), sold under the tradename Tegretol, among others, is a medication used primarily in the treatment of epilepsy and neuropathic pain.
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Carcinogen
A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis, the formation of cancer.
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Cardiac glycoside
Cardiac glycosides are a class of organic compounds that increase the output force of the heart and decrease its rate of contractions by acting on the cellular sodium-potassium ATPase pump.
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Cerebellum
The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates.
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Cerebral cortex
The cerebral cortex is the largest region of the cerebrum in the mammalian brain and plays a key role in memory, attention, perception, cognition, awareness, thought, language, and consciousness.
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Competition and Markets Authority
The Competition and Markets Authority (CMA) is a non-ministerial government department in the United Kingdom, responsible for strengthening business competition and preventing and reducing anti-competitive activities.
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CYP2C9
Cytochrome P450 2C9 (abbreviated CYP2C9) is an enzyme that in humans is encoded by the CYP2C9 gene.
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CYP3A4
Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.
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Cytochrome P450
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
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Developing country
A developing country (or a low and middle income country (LMIC), less developed country, less economically developed country (LEDC), underdeveloped country) is a country with a less developed industrial base and a low Human Development Index (HDI) relative to other countries.
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Digoxin toxicity
Digoxin toxicity, also known as digoxin poisoning, is a type of poisoning that occurs in people who take too much of the medication digoxin or eat plants such as foxglove that contain a similar substance.
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Diplopia
Diplopia, commonly known as double vision, is the simultaneous perception of two images of a single object that may be displaced horizontally, vertically, diagonally (i.e., both vertically and horizontally), or rotationally in relation to each other.
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Dreyfus Corporation
Dreyfus, established in 1951 and headquartered in New York City, is an American investment manager of investment products and strategies.
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Epileptic seizure
An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.
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Ethanol
Ethanol, also called alcohol, ethyl alcohol, grain alcohol, and drinking alcohol, is a chemical compound, a simple alcohol with the chemical formula.
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Exudate
An exudate is a fluid emitted by an organism through pores or a wound, a process known as exuding.
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Fetal alcohol spectrum disorder
Fetal alcohol spectrum disorders (FASDs) are a group of conditions that can occur in a person whose mother drank alcohol during pregnancy.
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Fetal hydantoin syndrome
Fetal hydantoin syndrome, also called fetal dilantin syndrome is a group of defects caused to the developing fetus by exposure to teratogenic effects of phenytoin or carbamazepine.
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Focal seizure
Focal seizures (also called partial seizures and localized seizures) are seizures which affect initially only one hemisphere of the brain.
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Folate deficiency
Folate deficiency is a low level of folic acid and derivatives in the body.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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Freiburg im Breisgau
Freiburg im Breisgau (Alemannic: Friburg im Brisgau; Fribourg-en-Brisgau) is a city in Baden-Württemberg, Germany, with a population of about 220,000.
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Gamma-glutamyl hydrolase
Gamma-glutamyl hydrolase is an enzyme that catalyses the following chemical reaction: This lysosomal or secreted, thiol-dependent peptidase, most active at acidic pH.
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Generalised tonic-clonic seizure
A generalized tonic–clonic seizure (formerly known as a grand mal seizure) is a type of generalized seizure that affects the entire brain.
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Germany
Germany (Deutschland), officially the Federal Republic of Germany (Bundesrepublik Deutschland), is a sovereign state in central-western Europe.
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Gingival enlargement
Gingival enlargement, (also termed gingival overgrowth, hypertrophic gingivitis, gingival hyperplasia, or gingival hypertrophy, and sometimes abbreviated to GO), is an increase in the size of the gingiva (gums).
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H. Houston Merritt
Hiram Houston Merritt (January 2, 1902, Wilmington, North Carolina – January 9, 1979 in Boston, Massachusetts) was one of the pre-eminent academic neurologists of his day.
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Health system
A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.
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Heart arrhythmia
Heart arrhythmia (also known as arrhythmia, dysrhythmia, or irregular heartbeat) is a group of conditions in which the heartbeat is irregular, too fast, or too slow.
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Heinrich Biltz
Heinrich Biltz (May 26, 1865 in Berlin – October 29, 1943 in Breslau) was a German chemist and professor.
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Hirsutism
Hirsutism is excessive body hair in men and women on parts of the body where hair is normally absent or minimal, such as on the chin or chest in particular, or the face or body in general.
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HLA-B
HLA-B (major histocompatibility complex, class I, B) is a human gene that provides instructions for making a protein that plays a critical role in the immune system.
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HLA-B75
HLA-B75 (B75) is an HLA-B serotype.
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Hydantoin
Hydantoin, or glycolylurea, is a heterocyclic organic compound with the formula CH2C(O)NHC(O)NH.
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Hypertrichosis
Hypertrichosis is an abnormal amount of hair growth over the body.
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Hypocalcaemia
Hypocalcaemia, also spelled hypocalcemia, is low calcium levels in the blood serum.
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Hypophosphatemia
Hypophosphatemia is an electrolyte disturbance in which there is an abnormally low level of phosphate in the blood.
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Hypotension
Hypotension is low blood pressure, especially in the arteries of the systemic circulation.
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Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
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Ireland
Ireland (Éire; Ulster-Scots: Airlann) is an island in the North Atlantic.
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Itch
Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch.
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Jack Dreyfus
John J. "Jack" Dreyfus, Sr. (August 28, 1913 – March 27, 2009) was an American financial expert and the founder of the Dreyfus Funds.
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Leukopenia
Leukopenia is a decrease in the number of white blood cells (leukocytes) found in the blood, which places individuals at increased risk of infection.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Major depressive disorder
Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.
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Megaloblastic anemia
Megaloblastic anemia (or megaloblastic anaemia) is an anemia (of macrocytic classification) that results from inhibition of DNA synthesis during red blood cell production.
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Microcephaly
Microcephaly is a medical condition in which the brain does not develop properly resulting in a smaller than normal head.
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Multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
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National Health Service
The National Health Service (NHS) is the name used for each of the public health services in the United Kingdom – the National Health Service in England, NHS Scotland, NHS Wales, and Health and Social Care in Northern Ireland – as well as a term to describe them collectively.
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National Institutes of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.
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Neuropathic pain
Neuropathic pain is pain caused by damage or disease affecting the somatosensory nervous system.
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Nystagmus
Nystagmus is a condition of involuntary (or voluntary, in rare cases) eye movement, acquired in infancy or later in life, that may result in reduced or limited vision.
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Parke-Davis
Parke-Davis is a subsidiary of the pharmaceutical company Pfizer.
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Peripheral neuropathy
Peripheral neuropathy (PN) is damage to or disease affecting nerves, which may impair sensation, movement, gland or organ function, or other aspects of health, depending on the type of nerve affected.
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Pfizer
Pfizer Inc. is an American pharmaceutical conglomerate headquartered in New York City, with its research headquarters in Groton, Connecticut.
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Pharmacodynamics
Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).
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Phenobarbital
Phenobarbital, also known as phenobarbitone or phenobarb, is a medication recommended by the World Health Organization for the treatment of certain types of epilepsy in developing countries.
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Post-tetanic potentiation
Post-Tetanic Potentiation (PTP) is a form of synaptic plasticity which is short-lived and results in increased frequency of miniature excitatory postsynaptic potentials (mEPSPs) or currents (EPSCs) with no effect on amplitude in the spontaneous postsynaptic potential.
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Potassium bromide
Potassium bromide (KBr) is a salt, widely used as an anticonvulsant and a sedative in the late 19th and early 20th centuries, with over-the-counter use extending to 1975 in the US.
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Pregnancy category
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy.
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Purple glove syndrome
Purple glove syndrome (PGS) is a poorly understood skin disease in which the extremities become swollen, discoloured and painful.
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Randomized controlled trial
A randomized controlled trial (or randomized control trial; RCT) is a type of scientific (often medical) experiment which aims to reduce bias when testing a new treatment.
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Richard Nixon
Richard Milhous Nixon (January 9, 1913 – April 22, 1994) was an American politician who served as the 37th President of the United States, serving from 1969 until 1974, when he resigned from office, the only U.S. president to do so.
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Sedation
Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.
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Selective immunoglobulin A deficiency
Selective immunoglobulin A (IgA) deficiency (SIgAD) is a genetic immunodeficiency, a type of hypogammaglobulinemia.
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Self-harm
Self-harm, also known as self-injury, is defined as the intentional, direct injuring of body tissue, done without suicidal intentions.
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Sinoatrial block
The initial impulse in a heart is usually formed in the Sinoatrial (SA) node and carried through the atria, down the internodal atrial pathways, and to the Atrioventricular (AV) node.
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Sinus bradycardia
Sinus bradycardia is a sinus rhythm with a rate that is lower than normal.
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Sodium channel
Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
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Somnolence
Somnolence (alternatively "sleepiness" or "drowsiness") is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).
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Status epilepticus
Status epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them.
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Stevens–Johnson syndrome
Stevens–Johnson syndrome (SJS) is a type of severe skin reaction.
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Systemic lupus erythematosus
Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.
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Temporal lobe
The temporal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals.
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Teratology
Teratology is the study of abnormalities of physiological development.
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Therapeutic index
The therapeutic index (TI; also referred to as therapeutic ratio) is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxicity.
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Thrombocytopenia
Thrombocytopenia is a condition characterized by abnormally low levels of thrombocytes, also known as platelets, in the blood.
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Toxic epidermal necrolysis
Toxic epidermal necrolysis (TEN) is a type of severe skin reaction.
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Tracy Putnam
Tracy Jackson Putnam (1894–1975) was the co-discoverer, together with H. Houston Merritt, of Dilantin for controlling epilepsy.
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Trade name
A trade name, trading name, or business name is a pseudonym frequently used by companies to operate under a name different from their registered, legal name.
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Tremor
A tremor is an involuntary, somewhat rhythmic, muscle contraction and relaxation involving oscillations or twitching movements of one or more body parts.
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Trigeminal neuralgia
Trigeminal neuralgia (TN or TGN) is a chronic pain disorder that affects the trigeminal nerve.
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Trimethoprim
Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections.
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United States dollar
The United States dollar (sign: $; code: USD; also abbreviated US$ and referred to as the dollar, U.S. dollar, or American dollar) is the official currency of the United States and its insular territories per the United States Constitution since 1792.
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Ventricular tachycardia
Ventricular tachycardia (V-tach or VT) is a type of regular and fast heart rate that arises from improper electrical activity in the ventricles of the heart.
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Vitamin D
Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and multiple other biological effects.
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Vitamin D deficiency
Vitamin D deficiency, or hypovitaminosis D, most commonly results from inadequate sunlight exposure (in particular sunlight with adequate ultraviolet B rays).
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Warfarin
Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant (blood thinner).
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WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
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Redirects here:
ATC code N03AB02, ATCvet code QN03AB02, Aleviatin, Antisacer, Auranile, Causoin, Citrullamon, Citrulliamon, Comitoina, Convul, Danten, Dantinal, Dantoinal, Dantoinal klinos, Dantoine, Denyl, Dephenylhydantoin, Di-Hydan, Di-Lan, Di-Phetine, Didan TDC 250, Difenilhidantoina, Difenin, Difetoin, Difhydan, Dihycon, Dilabid, Dilantin, Dilantin acid, Dilantin-125, Dilantine, Dillantin, Dintoin, Dintoina, Diphantoin, Diphedal, Diphedan, Diphenat, Diphenin, Diphenine, Dipheninum, Diphentoin, Diphentyn, Diphenylan, Diphenylhydantoin, Diphenylhydantoin sodium salt, Ditoinate, Ekko, Elepsindon, Enkelfel, Epamin, Epanutin, Epasmir 5, Epdantoin Simple, Epdantoine simple, Epelin, Epifenyl, Epihydan, Epilan, Epilan D, Epilan-D, Epilantin, Epinat, Epised, Eptal, Eptoin, Fenantoin, Fenidantoin s, Fentoin, Fenylepsin, Fenytoin Dak, Fenytoine, Gerot-epilan-D, Hidantal, Hidantilo, Hidantina, Hidantina senosian, Hidantina vitoria, Hidantomin, Hindatal, Hydantal, Hydantin, Hydantoin antenatal infection, Hydantoinal, Hydantol, Ictalis simple, Idantoil, Idantoin, Iphenylhydantoin, Kessodanten, Labopal, Lehydan, Lepitoin, Lepsin, Mesantoin, Minetoin, Neos-Hidantoina, Neosidantoina, Novantoina, Novophenytoin, Om hidantoina simple, Om-Hydantoine, Oxylan, Phanantin, Phanatine, Phenatoine, Phenhydan, Phenhydanin, Phenitoin, Phentoin, Phentytoin, Phenytek, Phenytex, Phenytoin sodium, Phenytoin-Gerot, Phenytonin, Prompt Phenytoin Sodium, Ritmenal, Saceril, Sanepil, Silantin, Sinergina, Sodanthon, Sodantoin, Sodanton, Solantin, Solantoin, Solantyl, Sylantoic, TOIN, Tacosal, Thilophenyl, Toin unicelles, Zentronal, Zentropil.
References
[1] https://en.wikipedia.org/wiki/Phenytoin
