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Omadacycline

Index Omadacycline

Omadacycline (formerly known as PTK-0796) is a broad spectrum antibiotic belonging to the aminomethylcycline subclass of tetracycline antibiotics. [1]

22 relations: Broad-spectrum antibiotic, Chlamydia infection, Community-acquired pneumonia, Efflux (microbiology), Food and Drug Administration, Gram-negative bacteria, Gram-positive bacteria, In vitro, In vivo, Legionella, Linezolid, Mark L. Nelson, Methicillin-resistant Staphylococcus aureus, Moxifloxacin, Phases of clinical research, Protein, Ribosomal protein, Skin and skin structure infection, Streptococcus pneumoniae, Tetracycline antibiotics, Urinary tract infection, Vancomycin-resistant Enterococcus.

Broad-spectrum antibiotic

The term broad-spectrum antibiotic can refer to an antibiotic that acts on the two major bacterial groups, gram-positive and gram-negative, or any antibiotic that acts against a wide range of disease-causing bacteria.

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Chlamydia infection

Chlamydia infection, often simply known as chlamydia, is a sexually transmitted infection caused by the bacterium Chlamydia trachomatis.

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Community-acquired pneumonia

Community-acquired pneumonia (CAP) refers to pneumonia (any of several lung diseases) contracted by a person with little contact with the healthcare system.

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Efflux (microbiology)

Active efflux is a mechanism responsible for moving compounds, like neurotransmitters, toxic substances, and antibiotics, out of the cell; this is considered to be a vital part of xenobiotic metabolism.

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Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

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Gram-negative bacteria

Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the gram-staining method of bacterial differentiation.

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Gram-positive bacteria

Gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their cell wall.

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In vitro

In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

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In vivo

Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

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Legionella

The genus Legionella is a pathogenic group of Gram-negative bacteria that includes the species L. pneumophila, causing legionellosis (all illnesses caused by Legionella) including a pneumonia-type illness called Legionnaires' disease and a mild flu-like illness called Pontiac fever.

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Linezolid

Linezolid is an antibiotic used for the treatment of infections caused by Gram-positive bacteria that are resistant to other antibiotics.

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Mark L. Nelson

Mark Nelson, Ph.D., is an American chemist, specializing in the field of antibiotics and tetracyclines.

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Methicillin-resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus (MRSA) refers to a group of gram-positive bacteria that are genetically distinct from other strains of Staphylococcus aureus.

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Moxifloxacin

Moxifloxacin, sold under the brandname Avelox among others, is an antibiotic used to treat a number of bacterial infections.

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Phases of clinical research

The phases of clinical research are the steps in which scientists do experiments with a health intervention in an attempt to find enough evidence for a process which would be useful as a medical treatment.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Ribosomal protein

A ribosomal protein (r-protein or rProtein) is any of the proteins that, in conjunction with rRNA, make up the ribosomal subunits involved in the cellular process of translation.

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Skin and skin structure infection

A skin and skin structure infection (SSSI), also referred to as skin and soft tissue infection (SSTI) or acute bacterial skin and skin structure infection (ABSSSI), is an infection of skin and associated soft tissues (such as loose connective tissue and mucous membranes).

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Streptococcus pneumoniae

Streptococcus pneumoniae, or pneumococcus, is a Gram-positive, alpha-hemolytic (under aerobic conditions) or beta-hemolytic (under anaerobic conditions), facultative anaerobic member of the genus Streptococcus.

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Tetracycline antibiotics

Tetracyclines are broad-spectrum antibiotics whose general usefulness has been reduced with the onset of antibiotic resistance.

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Urinary tract infection

A urinary tract infection (UTI) is an infection that affects part of the urinary tract.

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Vancomycin-resistant Enterococcus

Vancomycin-resistant Enterococcus, or vancomycin-resistant enterococci (VRE), are bacterial strains of the genus Enterococcus that are resistant to the antibiotic vancomycin.

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References

[1] https://en.wikipedia.org/wiki/Omadacycline

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