17 relations: Desipramine, Dopamine, Dopaminergic, DSP-4, Lesch–Nyhan syndrome, Monoamine transporter, MPTP, Neurotoxin, Norepinephrine, Norsalsolinol, Organic compound, Parkinson's disease, Parkinsonism, Rotenone, Substantia nigra, Superoxide, 5,7-Dihydroxytryptamine.
Desipramine (also known as desmethylimipramine) is a tricyclic antidepressant (TCA).
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Dopamine is an organic chemical of the catecholamine and phenethylamine families that plays a number of important roles in the human brain and body, as well as elsewhere in biology.
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Dopaminergic means "related to dopamine" (literally, "working on dopamine"), dopamine being a common neurotransmitter.
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For the Super NES enhancement chip see List of Super NES enhancement chips DSP-4, or N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine, is a neurotoxin selective for noradrenergic neurons, capable of crossing the blood–brain barrier.
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Lesch–Nyhan syndrome (LNS), also known as Nyhan's syndrome and juvenile gout, is a rare inherited disorder caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT), produced by mutations in the HPRT gene located on the X chromosome.
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Monoamine transporters (MATs) are protein structures that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters.
MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a neurotoxin precursor to MPP+, which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain.
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Neurotoxins are substances that are poisonous or destructive to nerve tissue.
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Norepinephrine, also called noradrenaline, is an organic chemical in the catecholamine family that functions in the human brain and body as a hormone and neurotransmitter.
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Norsalsolinol is a chemical compound that is produced naturally in the body through metabolism of dopamine.
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An organic compound is any member of a large class of gaseous, liquid, or solid chemical compounds whose molecules contain carbon.
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Parkinson's disease (PD, also known as idiopathic or primary parkinsonism, hypokinetic rigid syndrome (HRS), or paralysis agitans) is a degenerative disorder of the central nervous system mainly affecting the motor system.
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Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia, rigidity, and postural instability.
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Rotenone is an odorless, colorless, crystalline ketonic chemical compound used as a broad-spectrum insecticide, piscicide, and pesticide.
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The substantia nigra is a brain structure located in the mesencephalon (midbrain) that plays an important role in reward, addiction, and movement.
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A superoxide, also known by the obsolete name hyperoxide, is a compound that contains the superoxide anion with the chemical formula.
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5,7-Dihydroxytryptamine (5,7-DHT) is a purported neurotoxin used in scientific research to decrease concentrations of serotonin in the brain.