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P2Y receptor

P2Y receptors are a family of purinergic G protein-coupled receptors, stimulated by nucleotides such as ATP, ADP, UTP, UDP and UDP-glucose. [1]

32 relations: Adenosine diphosphate, Adenosine triphosphate, Caucasian race, Clopidogrel, Cystic fibrosis, G protein–coupled receptor, Gi alpha subunit, Gq alpha subunit, Gs alpha subunit, LPAR4, LPAR6, Lysophosphatidic acid, Myocardial infarction, Nucleotide, Orphan receptor, P2RY1, P2RY10, P2RY11, P2RY13, P2RY14, P2RY2, P2RY4, P2RY6, P2RY8, P2Y12, Polymorphism (biology), Purinergic receptor, Thienopyridine, Tissue (biology), Uridine diphosphate, Uridine diphosphate glucose, Uridine triphosphate.

Adenosine diphosphate

Adenosine diphosphate (ADP) (Adenosine pyrophosphate (APP)) is an important organic compound in metabolism and is essential to the flow of energy in living cells.

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Adenosine triphosphate

Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.

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Caucasian race

The Caucasian race (also Caucasoid or occasionally Europid) is a taxon historically used to describe the physical or biological type of some or all of the populations of Europe, North Africa, the Horn of Africa, Western Asia, Central Asia, and South Asia.

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Clopidogrel

Clopidogrel (INN) is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, cerebrovascular disease, and to prevent myocardial infarction (heart attack).

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Cystic fibrosis

Cystic fibrosis (CF), also known as mucoviscidosis, is a genetic disorder that affects mostly the lungs but also the pancreas, liver, kidneys and intestine.

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G protein–coupled receptor

G protein–coupled receptors (GPCRs), also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses.

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Gi alpha subunit

Gi alpha subunit (Gαi, or Gi/G0 or Gi protein) is a heterotrimeric G protein subunit that inhibits the production of cAMP from ATP.

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Gq alpha subunit

Gq protein (Gαq, or Gq/11) is a heterotrimeric G protein subunit that activates phospholipase C (PLC).

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Gs alpha subunit

The Gs alpha subunit (Gαs, Gsα, or Gs protein) is a heterotrimeric G protein subunit that activates the cAMP-dependent pathway by activating adenylyl cyclase.

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LPAR4

Lysophosphatidic acid receptor 4 also known as LPA4 is a protein that in humans is encoded by the LPAR4 gene.

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LPAR6

Lysophosphatidic acid receptor 6 also known as LPA6, P2RY5, and GPR87, is a protein that in humans is encoded by the LPAR6 gene.

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Lysophosphatidic acid

Lysophosphatidic acid (LPA) is a phospholipid derivative that can act as a signaling molecule.

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Myocardial infarction

Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle.

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Nucleotide

Nucleotides are organic molecules that serve as the monomers, or subunits, of nucleic acids like DNA and RNA.

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Orphan receptor

An orphan receptor is an apparent receptor that has a similar structure to other identified receptors but whose endogenous ligand has not yet been identified.

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P2RY1

P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.

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P2RY10

Putative P2Y purinoceptor 10 is a protein that in humans is encoded by the P2RY10 gene.

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P2RY11

P2Y purinoceptor 11 is a protein that in humans is encoded by the P2RY11 gene.

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P2RY13

P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.

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P2RY14

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.

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P2RY2

P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene.

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P2RY4

P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.

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P2RY6

P2Y purinoceptor 6 is a protein that in humans is encoded by the P2RY6 gene.

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P2RY8

P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.

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P2Y12

In the field of purinergic signaling, the P2Y12 protein is found mainly but not exclusively on the surface of blood platelets, and is an important regulator in blood clotting.

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Polymorphism (biology)

Polymorphism in biology is said to occur when two or more clearly different phenotypes exist in the same population of a species—in other words, the occurrence of more than one form or morph.

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Purinergic receptor

Purinergic receptors, also known as purinoceptors, are a family of plasma membrane molecules that are found in almost all mammalian tissues.

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Thienopyridine

Thienopyridines are a class of selective, irreversible ADP receptor/P2Y12 inhibitors used for their anti-platelet activity.

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Tissue (biology)

In biology, tissue is a cellular organizational level intermediate between cells and a complete organ.

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Uridine diphosphate

Uridine diphosphate, abbreviated UDP, is a nucleoside diphosphate.

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Uridine diphosphate glucose

Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar.

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Uridine triphosphate

Uridine-5'-triphosphate (UTP) is a pyrimidine nucleoside triphosphate, consisting of the organic base uracil linked to the 1' carbon of the ribose sugar, and esterified with tri-phosphoric acid at the 5' position.

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Redirects here:

ADP receptor, Adenosine diphosphate receptor, P 2 y, P2Y receptors, P2y receptor.

References

[1] https://en.wikipedia.org/wiki/P2Y_receptor

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