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PfSPZ Vaccine

Index PfSPZ Vaccine

PfSPZ Vaccine is a candidate malaria vaccine made of non-replicating irradiated whole sporozoites and developed by Sanaria. [1]

16 relations: Anopheles, Apicomplexan life cycle, Attenuated vaccine, CD8, Cytotoxic T cell, Fast track (FDA), Food and Drug Administration, Gamma delta T cell, Interferon gamma, Malaria, Malaria vaccine, Memory T cell, Plasmodium falciparum, RTS,S, Sanaria, T helper cell.

Anopheles

Anopheles (Greek anofelís: "useless") is a genus of mosquito first described and named by J. W. Meigen in 1818.

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Apicomplexan life cycle

Apicomplexans, a group of intracellular parasites, have life cycle stages evolved to allow them to survive the wide variety of environments they are exposed to during their complex life cycle.

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Attenuated vaccine

An attenuated vaccine is a vaccine created by reducing the virulence of a pathogen, but still keeping it viable (or "live").

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CD8

CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR).

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Cytotoxic T cell

A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways.

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Fast track (FDA)

Fast Track is a designation by the United States Food and Drug Administration (FDA) of an investigational drug for expedited review to facilitate development of drugs which treat a serious or life-threatening condition and fill an unmet medical need.

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Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

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Gamma delta T cell

Gamma delta T cells (γδ T cells) are T cells that have a distinctive T-cell receptor (TCR) on their surface.

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Interferon gamma

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons.

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Malaria

Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type.

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Malaria vaccine

Malaria vaccine is a vaccine that is used to prevent malaria.

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Memory T cell

Memory T cells are a subset of infection- and cancer-fighting T cells (also known as a T lymphocyte) that have previously encountered and responded to their cognate antigen; thus, the term antigen-experienced T cell is often applied.

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Plasmodium falciparum

Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that cause malaria in humans.

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RTS,S

RTS,S/AS01 — trade name Mosquirix — is a recombinant protein-based malaria vaccine.

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Sanaria

No description.

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T helper cell

The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system.

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Redirects here:

PFSPZ, PFSPZ vaccine, PfSPZ, PfSPZ vaccine.

References

[1] https://en.wikipedia.org/wiki/PfSPZ_Vaccine

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