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93 relations: Addiction, Agence Nationale de Sécurité du Médicament et des Produits de Santé, Alcohol (drug), Alcohol withdrawal syndrome, Alcoholism, Alphapharm, Anxiety, Anxiolytic, Auditory hallucination, Benzodiazepine, Benzodiazepine withdrawal syndrome, Bradycardia, Brain, Brain stimulation reward, Central nervous system, Cerebral palsy, Charcot–Marie–Tooth disease, Chloroform, Coma, Confusion, Craving (withdrawal), Crystal, Death, Delirium, Delusion, Depersonalization, Depressant, Dizziness, Drug overdose, Drug withdrawal, Dysautonomia, Epileptic seizure, Euphoria, Fever, GABA receptor agonist, GABAB receptor, GHB receptor, Hallucination, Hypertension, Hyperthermia, Hypertonia, Hyporeflexia, Hypothermia, Hypoventilation, Insomnia, Intrathecal administration, Intrathecal pump, Itch, Le Dernier Verre, Mallinckrodt, ..., Mania, Medication, Methanol, Molecular mass, Multiple sclerosis, Muscle relaxant, Naltrexone, Nausea, Neuroleptic malignant syndrome, Neurotransmitter, Novartis, Olivier Ameisen, Oral administration, Orientation (mental), Parkinson's disease, Percutaneous, Peripheral neuropathy, Phenibut, Pregabalin, Psychomotor agitation, Psychosis, Racemic mixture, Rebound effect, Sedation, Sedative, Solubility, Somnolence, Sorbitol, Spastic diplegia, Spasticity, Spinal cord, Stroke, Substance abuse, Suicide attempt, Sun Pharmaceutical, Tachycardia, Tactile hallucination, Thought disorder, Tremor, University of Amsterdam, Voltage-gated calcium channel, Vomiting, Weakness. Expand index (43 more) »
Addiction
Addiction is a brain disorder characterized by compulsive engagement in rewarding stimuli despite adverse consequences.
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Agence Nationale de Sécurité du Médicament et des Produits de Santé
Agence Nationale de Sécurité du Médicament et des Produits de Santé (ANSM) superseded the tasks and duties of Agence Française de Sécurité Sanitaire des Produits de Santé (AFSSAPS) on 1 May 2012.
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Alcohol (drug)
Alcohol, also known by its chemical name ethanol, is a psychoactive substance or drug that is the active ingredient in alcoholic beverages such as beer, wine, and distilled spirits (hard liquor).
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Alcohol withdrawal syndrome
Alcohol withdrawal syndrome is a set of symptoms that can occur following a reduction in alcohol use after a period of excessive use.
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Alcoholism
Alcoholism, also known as alcohol use disorder (AUD), is a broad term for any drinking of alcohol that results in mental or physical health problems.
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Alphapharm
Alphapharm is a generic drug manufacturing company based in Australia.
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Anxiety
Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behaviour such as pacing back and forth, somatic complaints, and rumination.
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Anxiolytic
An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.
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Auditory hallucination
A paracusia, or auditory hallucination, is a form of hallucination that involves perceiving sounds without auditory stimulus.
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Benzodiazepine
Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.
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Benzodiazepine withdrawal syndrome
Benzodiazepine withdrawal syndrome—often abbreviated to benzo withdrawal—is the cluster of symptoms that emerge when a person who has taken benzodiazepines, either medically or recreationally, and has developed a physical dependence undergoes dosage reduction or discontinuation.
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Bradycardia
Bradycardia is a condition wherein an individual has a very slow heart rate, typically defined as a resting heart rate of under 60 beats per minute (BPM) in adults.
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Brain
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.
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Brain stimulation reward
Brain stimulation reward (BSR) is a pleasurable phenomenon elicited via direct stimulation of specific brain regions, originally discovered by James Olds and Peter Milner.
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Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
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Cerebral palsy
Cerebral palsy (CP) is a group of permanent movement disorders that appear in early childhood.
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Charcot–Marie–Tooth disease
Charcot–Marie–Tooth disease (CMT) is one of the hereditary motor and sensory neuropathies, a group of varied inherited disorders of the peripheral nervous system characterized by progressive loss of muscle tissue and touch sensation across various parts of the body.
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Chloroform
Chloroform, or trichloromethane, is an organic compound with formula CHCl3.
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Coma
Coma is a state of unconsciousness in which a person cannot be awaken; fails to respond normally to painful stimuli, light, or sound; lacks a normal wake-sleep cycle; and does not initiate voluntary actions.
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Confusion
Confusion (from Latin confusĭo, -ōnis, from confundere: "to pour together;" "to mingle together;" "to confuse") is the state of being bewildered or unclear in one’s mind about something.
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Craving (withdrawal)
When going through withdrawal, craving is a psychological urge to administer a discontinued medication or recreational drug.
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Crystal
A crystal or crystalline solid is a solid material whose constituents (such as atoms, molecules, or ions) are arranged in a highly ordered microscopic structure, forming a crystal lattice that extends in all directions.
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Death
Death is the cessation of all biological functions that sustain a living organism.
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Delirium
Delirium, also known as acute confusional state, is an organically caused decline from a previously baseline level of mental function.
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Delusion
A delusion is a mistaken belief that is held with strong conviction even in the presence of superior evidence to the contrary.
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Depersonalization
Depersonalization can consist of a detachment within the self, regarding one's mind or body, or being a detached observer of oneself.
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Depressant
A depressant, or central depressant, is a drug that lowers neurotransmission levels, which is to depress or reduce arousal or stimulation, in various areas of the brain.
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Dizziness
Dizziness is an impairment in spatial perception and stability.
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Drug overdose
The term drug overdose (or simply overdose or OD) describes the ingestion or application of a drug or other substance in quantities greater than are recommended or generally practiced.
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Drug withdrawal
Drug withdrawal is the group of symptoms that occur upon the abrupt discontinuation or decrease in intake of medications or recreational drugs.
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Dysautonomia
Dysautonomia or autonomic dysfunction is a condition in which the autonomic nervous system (ANS) does not work properly.
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Epileptic seizure
An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.
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Euphoria
Euphoria is an affective state in which a person experiences pleasure or excitement and intense feelings of well-being and happiness.
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Fever
Fever, also known as pyrexia and febrile response, is defined as having a temperature above the normal range due to an increase in the body's temperature set-point.
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GABA receptor agonist
A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects.
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GABAB receptor
GABAB receptors (GABABR) are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA) that are linked via G-proteins to potassium channels.
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GHB receptor
The γ-hydroxybutyrate (GHB) receptor (GHBR), originally identified as GPR172A, is a G protein-coupled receptor (GPCR) that binds the neurotransmitter and psychoactive drug γ-hydroxybutyric acid (GHB).
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Hallucination
A hallucination is a perception in the absence of external stimulus that has qualities of real perception.
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Hypertension
Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.
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Hyperthermia
Hyperthermia is elevated body temperature due to failed thermoregulation that occurs when a body produces or absorbs more heat than it dissipates.
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Hypertonia
Hypertonia is a term sometimes used synonymously with spasticity and rigidity in the literature surrounding damage to the central nervous system, namely upper motor neuron lesions.
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Hyporeflexia
Hyporeflexia refers to below normal or absent reflexes (areflexia).
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Hypothermia
Hypothermia is reduced body temperature that happens when a body dissipates more heat than it absorbs.
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Hypoventilation
Hypoventilation (also known as respiratory depression) occurs when ventilation is inadequate (hypo meaning "below") to perform needed gas exchange.
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Insomnia
Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.
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Intrathecal administration
Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF) and is useful in spinal anaesthesia, chemotherapy, or pain management applications.
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Intrathecal pump
An intrathecal pump is a medical device used to deliver medications directly into the space between the spinal cord and the protective sheath surrounding the spinal cord.
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Itch
Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch.
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Le Dernier Verre
Le Dernier Verre (French for "The Last Glass") is a best-selling book by French cardiologist Olivier Ameisen that was published in 2008 and describes the author's experience of curing himself of alcoholism using the muscle relaxant, baclofen.
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Mallinckrodt
Mallinckrodt Pharmaceuticals, based in Staines-upon-Thames, England, with its U.S. headquarters in St. Louis, Missouri, produces specialty pharmaceutical products, including generic drugs and imaging agents.
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Mania
Mania, also known as manic syndrome, is a state of abnormally elevated arousal, affect, and energy level, or "a state of heightened overall activation with enhanced affective expression together with lability of affect." Although mania is often conceived as a "mirror image" to depression, the heightened mood can be either euphoric or irritable; indeed, as the mania intensifies, irritability can be more pronounced and result in violence, or anxiety.
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Medication
A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.
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Methanol
Methanol, also known as methyl alcohol among others, is a chemical with the formula CH3OH (a methyl group linked to a hydroxyl group, often abbreviated MeOH).
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Molecular mass
Relative Molecular mass or molecular weight is the mass of a molecule.
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Multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
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Muscle relaxant
A muscle relaxant is a drug that affects skeletal muscle function and decreases the muscle tone.
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Naltrexone
Naltrexone, sold under the brand names ReVia and Vivitrol among others, is a medication primarily used to manage alcohol or opioid dependence.
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Nausea
Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.
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Neuroleptic malignant syndrome
Neuroleptic malignant syndrome (NMS) is a life-threatening reaction that occasionally occurs in response to neuroleptic or antipsychotic medication.
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Neurotransmitter
Neurotransmitters are endogenous chemicals that enable neurotransmission.
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Novartis
Novartis International AG is a Swiss multinational pharmaceutical company based in Basel, Switzerland.
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Olivier Ameisen
Olivier Ameisen (June 25, 1953 – July 18, 2013) was a French-American cardiologist who wrote a best-selling book about curing alcoholism using the drug baclofen.
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Oral administration
| name.
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Orientation (mental)
Orientation is a function of the mind involving awareness of three dimensions: time, place and person.
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Parkinson's disease
Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.
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Percutaneous
In surgery, a percutaneous procedure is any medical procedure or method where access to inner organs or other tissue is done via needle-puncture of the skin, rather than by using an "open" approach where inner organs or tissue are exposed (typically with the use of a scalpel).
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Peripheral neuropathy
Peripheral neuropathy (PN) is damage to or disease affecting nerves, which may impair sensation, movement, gland or organ function, or other aspects of health, depending on the type of nerve affected.
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Phenibut
Phenibut, sold under the brand names Anvifen, Fenibut, and Noofen among others, is a central nervous system depressant with anxiolytic and sedative effects which is used in the treatment of anxiety, insomnia, and for a variety of other indications.
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Pregabalin
Pregabalin, marketed under the brand name Lyrica among others, is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder.
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Psychomotor agitation
Psychomotor agitation is a set of signs and symptoms that stem from mental tension and anxiety.
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Psychosis
Psychosis is an abnormal condition of the mind that results in difficulties telling what is real and what is not.
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Racemic mixture
In chemistry, a racemic mixture, or racemate, is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule.
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Rebound effect
The rebound effect, or rebound phenomenon, is the emergence or re-emergence of symptoms that were either absent or controlled while taking a medication, but appear when that same medication is discontinued, or reduced in dosage.
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Sedation
Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.
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Sedative
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.
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Solubility
Solubility is the property of a solid, liquid or gaseous chemical substance called solute to dissolve in a solid, liquid or gaseous solvent.
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Somnolence
Somnolence (alternatively "sleepiness" or "drowsiness") is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).
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Sorbitol
Sorbitol, less commonly known as glucitol, is a sugar alcohol with a sweet taste which the human body metabolizes slowly.
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Spastic diplegia
Spastic diplegia, historically known as Little's Disease, is a form of cerebral palsy (CP) that is a chronic neuromuscular condition of hypertonia and spasticity—manifested as an especially high and constant "tightness" or "stiffness"—in the muscles of the lower extremities of the human body, usually those of the legs, hips and pelvis.
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Spasticity
Spasticity is a feature of altered skeletal muscle performance with a combination of paralysis, increased tendon reflex activity, and hypertonia.
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Spinal cord
The spinal cord is a long, thin, tubular bundle of nervous tissue and support cells that extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column.
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Stroke
A stroke is a medical condition in which poor blood flow to the brain results in cell death.
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Substance abuse
Substance abuse, also known as drug abuse, is a patterned use of a drug in which the user consumes the substance in amounts or with methods which are harmful to themselves or others, and is a form of substance-related disorder.
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Suicide attempt
A suicide attempt is an attempt where a person tries to commit suicide but survives.
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Sun Pharmaceutical
Sun Pharmaceutical Industries Limited is an Indian multinational pharmaceutical company headquartered in Mumbai, Maharashtra that manufactures and sells pharmaceutical formulations and active pharmaceutical ingredients (APIs) primarily in India and the United States.
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Tachycardia
Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.
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Tactile hallucination
Tactile hallucination is the false perception of tactile sensory input that creates a hallucinatory sensation of physical contact with an imaginary object.
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Thought disorder
Thought disorder (TD) or formal thought disorder (FTD) refers to disorganized thinking as evidenced by disorganized speech.
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Tremor
A tremor is an involuntary, somewhat rhythmic, muscle contraction and relaxation involving oscillations or twitching movements of one or more body parts.
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University of Amsterdam
The University of Amsterdam (abbreviated as UvA, Universiteit van Amsterdam) is a public university located in Amsterdam, Netherlands.
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Voltage-gated calcium channel
Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the calcium ion Ca2+.
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Vomiting
Vomiting, also known as emesis, puking, barfing, throwing up, among other terms, is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.
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Weakness
Weakness or asthenia is a symptom of a number of different conditions.
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Redirects here:
ATC code M03BX01, ATCvet code QM03BX01, Apo-Baclofen, Baclon, Baklofen, C10H12ClNO2, Gablofen, Kemstro, Lioresal, Lioresal Intrathecal, Novo-Baclofen, Nu-Baclofen, Pms-Baclofen.
References
[1] https://en.wikipedia.org/wiki/Baclofen
