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94 relations: Adenosine, Alfred Werner, Alkyl, Alkylation, Allergy, Amifostine, Ammonia, Apoptosis, Aprepitant, Aquation, Auger therapy, Barnett Rosenberg, Bladder cancer, Bone marrow suppression, Brain tumor, Breast cancer, Cancer, Carboplatin, Carcinoma, Cardiovascular disease, Cervical cancer, Chemical & Engineering News, Chemical Reviews, Chemotherapy, Cis–trans isomerism, Corticosteroid, Developing country, Dexamethasone, Dicycloplatin, Dimethyl sulfoxide, Diuretic, DNA, DNA repair, DNA replication, Electrolysis, Electrolyte imbalance, Escherichia coli, Esophageal cancer, Food and Drug Administration, Germ cell tumor, Granisetron, Guanine, Head and neck cancer, Health system, Hearing loss, Hemolysis, Hemolytic anemia, High-mobility group, HtrA serine peptidase 2, Hydrochloric acid, ..., Intravenous therapy, Journal of Chemical Education, Kidney failure, Lung cancer, Lymphoma, Melanin, Mesothelioma, Metal aquo complex, Michigan State University, Mitosis, National Cancer Institute, National Health Service, Nausea, Nephrotoxicity, Nerve conduction study, Neuroblastoma, Neurotoxicity, Nucleotide, Nucleotide excision repair, Ondansetron, Ototoxicity, Ovarian cancer, Oxaliplatin, Paclitaxel, Platinum-based antineoplastic, Potassium chloride, Potassium iodide, Potassium tetrachloroplatinate, Purine, Radical (chemistry), Rat, Reactive oxygen species, Renal function, Sarcoma, Silver iodide, Silver nitrate, Sodium–hydrogen antiporter 1, Stereoisomerism, Stria vascularis of cochlear duct, Testicular cancer, Trans effect, Trans-dichlorodiammineplatinum(II), Vomiting, WHO Model List of Essential Medicines. Expand index (44 more) »
Adenosine
Adenosine is both a chemical found in many living systems and a medication.
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Alfred Werner
Alfred Werner (12 December 1866 – 15 November 1919) was a Swiss chemist who was a student at ETH Zurich and a professor at the University of Zurich.
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Alkyl
In organic chemistry, an alkyl substituent is an alkane missing one hydrogen.
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Alkylation
Alkylation is the transfer of an alkyl group from one molecule to another.
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Allergy
Allergies, also known as allergic diseases, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.
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Amifostine
Amifostine (Ethiofos) is a cytoprotective adjuvant used in cancer chemotherapy and radiotherapy involving DNA-binding chemotherapeutic agents.
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Ammonia
Ammonia is a compound of nitrogen and hydrogen with the formula NH3.
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Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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Aprepitant
Aprepitant (brand name: Emend (the brand name used in all English-speaking countries)) is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA).
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Aquation
Aquation is the chemical reaction involving "incorporation of one or more integral molecules of water".
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Auger therapy
Auger therapy (AT) is a form of radiation therapy for the treatment of cancer which relies on a large number of low-energy electrons (emitted by the Auger effect) to damage cancer cells, rather than the high-energy radiation used in traditional radiation therapy.
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Barnett Rosenberg
Barnett Rosenberg (16 November 1926 – 8 August 2009) was an American chemist best known for the discovery of the anti-cancer drug cisplatin.
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Bladder cancer
Bladder cancer is any of several types of cancer arising from the tissues of the urinary bladder.
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Bone marrow suppression
Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).
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Brain tumor
A brain tumor occurs when abnormal cells form within the brain.
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Carboplatin
Carboplatin, sold under the trade name Paraplatin among others, is a chemotherapy medication used to treat a number of forms of cancer.
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Carcinoma
Carcinoma is a type of cancer that develops from epithelial cells.
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Cardiovascular disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels.
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Cervical cancer
Cervical cancer is a cancer arising from the cervix.
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Chemical & Engineering News
Chemical & Engineering News (C&EN) is a weekly trade magazine published by the American Chemical Society, providing professional and technical information in the fields of chemistry and chemical engineering.
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Chemical Reviews
Chemical Reviews is peer-reviewed scientific journal published twice per month by the American Chemical Society.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Cis–trans isomerism
Cis–trans isomerism, also known as geometric isomerism or configurational isomerism, is a term used in organic chemistry.
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Corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.
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Developing country
A developing country (or a low and middle income country (LMIC), less developed country, less economically developed country (LEDC), underdeveloped country) is a country with a less developed industrial base and a low Human Development Index (HDI) relative to other countries.
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Dexamethasone
Dexamethasone is a type of corticosteroid medication.
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Dicycloplatin
Dicycloplatin is a chemotherapy medication used to treat a number of cancers which includes the Non-small-cell lung carcinoma and prostate cancer..
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Dimethyl sulfoxide
Dimethyl sulfoxide (DMSO) is an organosulfur compound with the formula (CH3)2SO.
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Diuretic
A diuretic is any substance that promotes diuresis, the increased production of urine.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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DNA repair
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.
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DNA replication
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.
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Electrolysis
In chemistry and manufacturing, electrolysis is a technique that uses a direct electric current (DC) to drive an otherwise non-spontaneous chemical reaction.
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Electrolyte imbalance
Electrolyte imbalance is an abnormality in the concentration of electrolytes in the body.
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Escherichia coli
Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).
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Esophageal cancer
Esophageal cancer is cancer arising from the esophagus—the food pipe that runs between the throat and the stomach.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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Germ cell tumor
A germ cell tumor (GCT) is a neoplasm derived from germ cells.
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Granisetron
Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.
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Guanine
Guanine (or G, Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA).
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Head and neck cancer
Head and neck cancer is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands.
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Health system
A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.
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Hearing loss
Hearing loss, also known as hearing impairment, is a partial or total inability to hear.
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Hemolysis
Hemolysis or haemolysis, also known by several other names, is the rupturing (lysis) of red blood cells (erythrocytes) and the release of their contents (cytoplasm) into surrounding fluid (e.g. blood plasma).
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Hemolytic anemia
Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular, but usually in the spleen).
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High-mobility group
High-Mobility Group or HMG is a group of chromosomal proteins that are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair.
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HtrA serine peptidase 2
Serine protease HTRA2, mitochondrial is an enzyme that in humans is encoded by the HTRA2 gene.
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Hydrochloric acid
Hydrochloric acid is a colorless inorganic chemical system with the formula.
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Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
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Journal of Chemical Education
The Journal of Chemical Education is a monthly peer-reviewed academic journal available in both print and electronic versions.
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Kidney failure
Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys no longer work.
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Lung cancer
Lung cancer, also known as lung carcinoma, is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung.
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Lymphoma
Lymphoma is a group of blood cancers that develop from lymphocytes (a type of white blood cell).
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Melanin
Melanin (from μέλας melas, "black, dark") is a broad term for a group of natural pigments found in most organisms.
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Mesothelioma
Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs (known as the mesothelium).
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Metal aquo complex
Metal aquo complexes are coordination compounds containing metal ions with only water as a ligand.
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Michigan State University
Michigan State University (MSU) is a public research university in East Lansing, Michigan, United States.
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Mitosis
In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.
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National Cancer Institute
The National Cancer Institute (NCI) is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services.
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National Health Service
The National Health Service (NHS) is the name used for each of the public health services in the United Kingdom – the National Health Service in England, NHS Scotland, NHS Wales, and Health and Social Care in Northern Ireland – as well as a term to describe them collectively.
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Nausea
Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.
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Nephrotoxicity
Nephrotoxicity is toxicity in the kidneys.
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Nerve conduction study
A nerve conduction study (NCS) is a medical diagnostic test commonly used to evaluate the function, especially the ability of electrical conduction, of the motor and sensory nerves of the human body.
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Neuroblastoma
Neuroblastoma (NB) is a type of cancer that forms in certain types of nerve tissue. It most frequently starts from one of the adrenal glands, but can also develop in the neck, chest, abdomen, or spine. Symptoms may include bone pain, a lump in the abdomen, neck, or chest, or a painless bluish lump under the skin. Occasionally, neuroblastoma may be due to a mutation inherited from a person's parents. Environmental factors have not been found to be involved. Diagnosis is based on a tissue biopsy. Occasionally it may be found in a baby by ultrasound during pregnancy. At diagnosis, the cancer has usually already spread. The cancer is divided into low-, intermediate-, and high-risk groups based on a child's age, cancer stage, and what the cancer looks like. Treatment and outcomes depends on the risk group a person is in. Treatments may include observation, surgery, radiation, chemotherapy, or stem cell transplantation. Low-risk disease in babies typically has a good outcome with surgery or simply observation. In high-risk disease, chances of long-term survival, however, are less than 40% despite aggressive treatment. Neuroblastoma is the most common cancer in babies and the third-most common cancer in children after leukemia and brain cancer. About one in every 7,000 children is affected at some time. About 90% of cases occur in children less than 5 years old and it is rare in adults. Of cancer deaths in children, about 15% are due to neuroblastoma. The disease was first described in the 1800s.
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Neurotoxicity
Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system.
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Nucleotide
Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.
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Nucleotide excision repair
Nucleotide excision repair is a DNA repair mechanism.
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Ondansetron
Ondansetron, marketed under the brand name Zofran, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery.
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Ototoxicity
Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug.
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Ovarian cancer
Ovarian cancer is a cancer that forms in or on an ovary.
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Oxaliplatin
Oxaliplatin, sold under the brand name Eloxatin, is a cancer medication used to treat colorectal cancer.
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Paclitaxel
Paclitaxel (PTX), sold under the brand name Taxol among others, is a chemotherapy medication used to treat a number of types of cancer.
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Platinum-based antineoplastic
Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer.
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Potassium chloride
Potassium chloride (KCl) is a metal halide salt composed of potassium and chlorine.
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Potassium iodide
Potassium iodide is a chemical compound, medication, and dietary supplement.
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Potassium tetrachloroplatinate
Potassium tetrachloroplatinate(II) is the chemical compound with the formula K2PtCl4.
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Purine
A purine is a heterocyclic aromatic organic compound that consists of a pyrimidine ring fused to an imidazole ring.
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Radical (chemistry)
In chemistry, a radical (more precisely, a free radical) is an atom, molecule, or ion that has an unpaired valence electron.
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Rat
Rats are various medium-sized, long-tailed rodents in the superfamily Muroidea.
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Reactive oxygen species
Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen.
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Renal function
Renal function, in nephrology, is an indication of the kidney's condition and its role in renal physiology.
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Sarcoma
A sarcoma is a cancer that arises from transformed cells of mesenchymal origin.
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Silver iodide
Silver iodide is an inorganic compound with the formula AgI. The compound is a bright yellow solid, but samples almost always contain impurities of metallic silver that give a gray coloration. The silver contamination arises because AgI is highly photosensitive. This property is exploited in silver-based photography. Silver iodide is also used as an antiseptic and in cloud seeding.
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Silver nitrate
Silver nitrate is an inorganic compound with chemical formula.
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Sodium–hydrogen antiporter 1
The sodium-hydrogen antiporter 1 (NHE-1) also known as sodium/hydrogen exchanger 1 or SLC9A1 (SoLute Carrier family 9A1) is an isoform of sodium–hydrogen antiporter that in humans is encoded by the SLC9A1 gene.
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Stereoisomerism
In stereochemistry, stereoisomers are isomeric molecules that have the same molecular formula and sequence of bonded atoms (constitution), but differ in the three-dimensional orientations of their atoms in space.
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Stria vascularis of cochlear duct
The upper portion of the spiral ligament (which forms the outer wall of the cochlear duct) contains numerous capillary loops and small blood vessels, and is termed the stria vascularis.
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Testicular cancer
Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system.
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Trans effect
In inorganic chemistry, the trans effect is the labilization (making more reactive) of ligands that are trans to certain other ligands, which can thus be regarded as trans-directing ligands.
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Trans-dichlorodiammineplatinum(II)
Trans-dichlorodiammineplatinum(II) is the coordination complex with the formula PtCl2(NH3)2.
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Vomiting
Vomiting, also known as emesis, puking, barfing, throwing up, among other terms, is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.
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WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
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Redirects here:
ATC code L01XA01, ATCvet code QL01XA01, Abiplatin, Biocisplatinum, Briplatin, CDDP, Cis Pt II, Cis platin, Cis-DDP, Cis-diamminedichloroplatinum, Cis-diamminedichloroplatinum(II), Cis-platin, Cis-platinum, Cis-platinum(II) chloride diammine, Cismaplat, Cisplatine, Cisplatinol, Cisplatinum, Cisplatyl, Citoplationo, H6cl2n2pt, Lederplatin, Neoplatin, Peyrone's salt, Platamine, Platiblastin, Platidiam, Platinex, Platinol, Platinol-AQ, Platinoxan, PtCl2(NH3)2, Transplatin.
References
[1] https://en.wikipedia.org/wiki/Cisplatin
