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Q cycle

The Q cycle (named for CoQ10) describes a series of reactions that describe how the sequential oxidation and reduction of the lipid-loving electron carrier, Coenzyme Q10 (CoQ10), between the ubiquinol and ubiquinone forms, can result in the net pumping of protons across a lipid bilayer (in the case of mitochondria, the inner mitochondrial membrane). [1]

16 relations: Adenosine triphosphate, Coenzyme Q – cytochrome c reductase, Coenzyme Q10, Cytochrome b, Cytochrome c, Cytochrome c oxidase, Heme, Hydrogen bond, Lipid, Mitochondrion, Peter D. Mitchell, Propionate, Proton, Rieske protein, Semiquinone, Ubiquinol.

Adenosine triphosphate

Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.

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Coenzyme Q – cytochrome c reductase

The coenzyme Q: cytochrome c — oxidoreductase, sometimes called the cytochrome bc1 complex, and at other times complex III, is the third complex in the electron transport chain, playing a critical role in biochemical generation of ATP (oxidative phosphorylation).

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Coenzyme Q10

Coenzyme Q10, also known as ubiquinone, ubidecarenone, coenzyme Q, and abbreviated at times to CoQ10, CoQ, or Q10 is a 1,4-benzoquinone, where Q refers to the quinone chemical group, and 10 refers to the number of isoprenyl chemical subunits in its tail.

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Cytochrome b

Cytochrome b is a protein found in the mitochondria of eukaryotic cells.

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Cytochrome c

The cytochrome complex, or cyt c is a small hemeprotein found loosely associated with the inner membrane of the mitochondrion.

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Cytochrome c oxidase

The enzyme cytochrome c oxidase, or Complex IV, is a large transmembrane protein complex found in bacteria and the mitochondrion of eukaryotes.

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Heme

Heme (American English) or haem (British English) is a cofactor consisting of an Fe2+ (ferrous) ion contained in the centre of a large heterocyclic organic ring called a porphyrin, made up of four pyrrolic groups joined together by methine bridges.

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Hydrogen bond

A hydrogen bond is the electrostatic attraction between polar molecules that occurs when a hydrogen (H) atom bound to a highly electronegative atom such as nitrogen (N), oxygen (O) or fluorine (F) experiences attraction to some other nearby highly electronegative atom.

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Lipid

Lipids are a group of naturally occurring molecules that include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E, and K), monoglycerides, diglycerides, triglycerides, phospholipids, and others.

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Mitochondrion

The mitochondrion (plural mitochondria) is a double membrane-bound organelle found in most eukaryotic cells.

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Peter D. Mitchell

Peter Dennis Mitchell, FRS (29 September 1920 – 10 April 1992) was a British biochemist who was awarded the 1978 Nobel Prize for Chemistry for his discovery of the chemiosmotic mechanism of ATP synthesis.

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Propionate

The propionate or propanoate ion is C2H5COO− (the conjugate base of propionic acid).

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Proton

| magnetic_moment.

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Rieske protein

Rieske proteins are iron-sulfur protein (ISP) components of cytochrome ''bc''1 complexes and cytochrome b6f complexes which were first discovered and isolated by John S. Rieske and co-workers in 1964.

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Semiquinone

Semiquinone (or ubisemiquinone) is a free radical resulting from the removal of one hydrogen atom with its electron during the process of dehydrogenation of a hydroquinone to quinone or alternatively the addition of a single H atom to a quinone.

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Ubiquinol

Ubiquinol is an electron-rich (reduced) form of coenzyme Q10.

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References

[1] https://en.wikipedia.org/wiki/Q_cycle

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