Faster access than browser!
134 relations: Active immunotherapy, Adenosine triphosphate, Amgen, Angiogenesis, Antagonist, Antibody, Antibody-dependent cell-mediated cytotoxicity, Antigen, AP-1 transcription factor, Autism, Autocrine signalling, Avidity, AXL receptor tyrosine kinase, Beta-catenin, Biological activity, Bone remodeling, C-Met inhibitor, Cancer stem cell, CBL (gene), CD117, CDH1 (gene), Cell growth, Cell migration, Cell surface receptor, Clear-cell adenocarcinoma, Colorectal cancer, Complement system, Complement-dependent cytotoxicity, Compugen (Israeli company), Cytokine, Cytotoxicity, Dissociation constant, Disulfide, DLL3, Ectodomain, Ectodysplasin A, Embryogenesis, Endocytosis, Endothelium, Epidermal growth factor receptor, Epithelial–mesenchymal transition, Epithelium, Epitope, ETS transcription factor family, ETS1, Fermentek, Food and Drug Administration, Foretinib, Fungus, Furin, ..., Gastrulation, Gene, Germinal disc, GLMN, GRB2, Growth factor, Haematopoiesis, Head and neck cancer, Hepatocyte, Hepatocyte growth factor, Hypoxia (medical), Hypoxia-inducible factors, Immunotherapy, Interferon, Interleukin, Interleukin 2, K252a, Kinase insert domain receptor, Liver, Macrophage, Melanocyte, Mesenchymal stem cell, Mesenchyme, Metalloproteinase, Metastasis, Mir-199 microRNA precursor, Mitogen, Mitogen-activated protein kinase, Monoclonal antibody, Morphogenesis, Myocyte, Natural killer cell, Nerve, Neuron, Neutrophil, Notch signaling pathway, PAK1, Pfizer, Phagocyte, Phagocytosis, Phenotype, Phosphatase, Phosphoinositide 3-kinase, Platelet-derived growth factor receptor, Progenitor cell, Protease, Proteasome, Protein, Protein kinase B, Protein–protein interaction, Proto-oncogene tyrosine-protein kinase Src, PTEN (gene), PTPRM, RAC1, RANBP9, Ras subfamily, Receptor tyrosine kinase, Renal cell carcinoma, Scattering, Schizophrenia, Semaphorin, SH2 domain, SHC1, Signal transduction, STAT protein, STAT3, Staurosporine, Stem cell, Stomach cancer, SUGEN, Swiss Institute of Bioinformatics, Tivantinib, Tpr-met fusion protein, Transcription factor, Tumor antigen, Tumor suppressor, Tyrosine kinase, Ubiquitin, Ubiquitin ligase, Von Hippel–Lindau tumor suppressor, White blood cell, Wild type, Wnt signaling pathway, Wound healing. Expand index (84 more) »
Active immunotherapy
Active immunotherapy is a type of immunotherapy that aims to stimulate the host's immune system or a specific immune response to a disease or pathogen and is most commonly used in cancer treatments.
New!!: C-Met and Active immunotherapy · See more »
Adenosine triphosphate
Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.
New!!: C-Met and Adenosine triphosphate · See more »
Amgen
Amgen Inc. (formerly Applied Molecular Genetics Inc.) is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California.
New!!: C-Met and Amgen · See more »
Angiogenesis
Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.
New!!: C-Met and Angiogenesis · See more »
Antagonist
An antagonist is a character, group of characters, institution or concept that stands in or represents opposition against which the protagonist(s) must contend.
New!!: C-Met and Antagonist · See more »
Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
New!!: C-Met and Antibody · See more »
Antibody-dependent cell-mediated cytotoxicity
The antibody-dependent cell-mediated cytotoxicity (ADCC), also referred to as antibody-dependent cellular cytotoxicity, is a mechanism of cell-mediated immune defense whereby an effector cell of the immune system actively lyses a target cell, whose membrane-surface antigens have been bound by specific antibodies.
New!!: C-Met and Antibody-dependent cell-mediated cytotoxicity · See more »
Antigen
In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.
New!!: C-Met and Antigen · See more »
AP-1 transcription factor
Activator protein 1 (AP-1) is a transcription factor that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections.
New!!: C-Met and AP-1 transcription factor · See more »
Autism
Autism is a developmental disorder characterized by troubles with social interaction and communication and by restricted and repetitive behavior.
New!!: C-Met and Autism · See more »
Autocrine signalling
Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on that same cell, leading to changes in the cell.
New!!: C-Met and Autocrine signalling · See more »
Avidity
In biochemistry, avidity refers to the accumulated strength of multiple affinities of individual non-covalent binding interactions, such as between a protein receptor and its ligand, and is commonly referred to as functional affinity.
New!!: C-Met and Avidity · See more »
AXL receptor tyrosine kinase
Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene.
New!!: C-Met and AXL receptor tyrosine kinase · See more »
Beta-catenin
Catenin beta-1, also known as β-catenin, is a protein that in humans is encoded by the CTNNB1 gene.
New!!: C-Met and Beta-catenin · See more »
Biological activity
In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter.
New!!: C-Met and Biological activity · See more »
Bone remodeling
Bone remodeling (or bone metabolism) is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).
New!!: C-Met and Bone remodeling · See more »
C-Met inhibitor
c-Met inhibitors are a class of small molecules that inhibit the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter factor (HGF/SF).
New!!: C-Met and C-Met inhibitor · See more »
Cancer stem cell
Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample.
New!!: C-Met and Cancer stem cell · See more »
CBL (gene)
Cbl (named after Casitas B-lineage Lymphoma) is a mammalian gene encoding the protein CBL which is an E3 ubiquitin-protein ligase involved in cell signalling and protein ubiquitination.
New!!: C-Met and CBL (gene) · See more »
CD117
Mast/stem cell growth factor receptor (SCFR), also known as proto-oncogene c-Kit or tyrosine-protein kinase Kit or CD117, is a receptor tyrosine kinase protein that in humans is encoded by the KIT gene.
New!!: C-Met and CD117 · See more »
CDH1 (gene)
Cadherin-1 also known as CAM 120/80 or epithelial cadherin (E-cadherin) or uvomorulin is a protein that in humans is encoded by the CDH1 gene.
New!!: C-Met and CDH1 (gene) · See more »
Cell growth
The term cell growth is used in the contexts of biological cell development and cell division (reproduction).
New!!: C-Met and Cell growth · See more »
Cell migration
Cell migration is a central process in the development and maintenance of multicellular organisms.
New!!: C-Met and Cell migration · See more »
Cell surface receptor
Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the membranes of cells.
New!!: C-Met and Cell surface receptor · See more »
Clear-cell adenocarcinoma
Clear-cell adenocarcinoma is a type of adenocarcinoma that shows clear cells.
New!!: C-Met and Clear-cell adenocarcinoma · See more »
Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
New!!: C-Met and Colorectal cancer · See more »
Complement system
The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.
New!!: C-Met and Complement system · See more »
Complement-dependent cytotoxicity
Complement-dependent cytotoxicity (CDC) is a function of the complement system.
New!!: C-Met and Complement-dependent cytotoxicity · See more »
Compugen (Israeli company)
Compugen Ltd.
New!!: C-Met and Compugen (Israeli company) · See more »
Cytokine
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
New!!: C-Met and Cytokine · See more »
Cytotoxicity
Cytotoxicity is the quality of being toxic to cells.
New!!: C-Met and Cytotoxicity · See more »
Dissociation constant
In chemistry, biochemistry, and pharmacology, a dissociation constant (K_d) is a specific type of equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions.
New!!: C-Met and Dissociation constant · See more »
Disulfide
In chemistry, a disulfide refers to a functional group with the structure R−S−S−R′.
New!!: C-Met and Disulfide · See more »
DLL3
Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene.
New!!: C-Met and DLL3 · See more »
Ectodomain
An ectodomain is the domain of a membrane protein that extends into the extracellular space (the space outside a cell).
New!!: C-Met and Ectodomain · See more »
Ectodysplasin A
Ectodysplasin A (EDA) is a protein that in humans is encoded by the EDA gene.
New!!: C-Met and Ectodysplasin A · See more »
Embryogenesis
Embryogenesis is the process by which the embryo forms and develops.
New!!: C-Met and Embryogenesis · See more »
Endocytosis
Endocytosis is a form of bulk transport in which a cell transports molecules (such as proteins) into the cell (endo- + cytosis) by engulfing them in an energy-using process.
New!!: C-Met and Endocytosis · See more »
Endothelium
Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.
New!!: C-Met and Endothelium · See more »
Epidermal growth factor receptor
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands.
New!!: C-Met and Epidermal growth factor receptor · See more »
Epithelial–mesenchymal transition
The epithelial–mesenchymal transition (EMT) is a process by which epithelial cells lose their cell polarity and cell-cell adhesion, and gain migratory and invasive properties to become mesenchymal stem cells; these are multipotent stromal cells that can differentiate into a variety of cell types.
New!!: C-Met and Epithelial–mesenchymal transition · See more »
Epithelium
Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.
New!!: C-Met and Epithelium · See more »
Epitope
An epitope, also known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, or T cells.
New!!: C-Met and Epitope · See more »
ETS transcription factor family
In the field of molecular biology, the ETS (E26 transformation-specific or E-twenty-six) family is one of the largest families of transcription factors and is unique to animals.
New!!: C-Met and ETS transcription factor family · See more »
ETS1
Protein C-ets-1 is a protein that in humans is encoded by the ETS1 gene.
New!!: C-Met and ETS1 · See more »
Fermentek
Fermentek Ltd. is a biotechnological company in the Atarot industrial zone of Jerusalem, Israel.
New!!: C-Met and Fermentek · See more »
Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
New!!: C-Met and Food and Drug Administration · See more »
Foretinib
Foretinib is an experimental drug candidate for the treatment of cancer.
New!!: C-Met and Foretinib · See more »
Fungus
A fungus (plural: fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.
New!!: C-Met and Fungus · See more »
Furin
Furin is a protein that in humans is encoded by the FURIN gene.
New!!: C-Met and Furin · See more »
Gastrulation
Gastrulation is a phase early in the embryonic development of most animals, during which the single-layered blastula is reorganized into a multilayered structure known as the gastrula.
New!!: C-Met and Gastrulation · See more »
Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
New!!: C-Met and Gene · See more »
Germinal disc
Germinal disc may refer to.
New!!: C-Met and Germinal disc · See more »
GLMN
Glomulin is a protein that in humans is encoded by the GLMN gene.
New!!: C-Met and GLMN · See more »
GRB2
Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein involved in signal transduction/cell communication.
New!!: C-Met and GRB2 · See more »
Growth factor
A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.
New!!: C-Met and Growth factor · See more »
Haematopoiesis
Haematopoiesis (from Greek αἷμα, "blood" and ποιεῖν "to make"; also hematopoiesis in American English; sometimes also haemopoiesis or hemopoiesis) is the formation of blood cellular components.
New!!: C-Met and Haematopoiesis · See more »
Head and neck cancer
Head and neck cancer is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands.
New!!: C-Met and Head and neck cancer · See more »
Hepatocyte
A hepatocyte is a cell of the main parenchymal tissue of the liver.
New!!: C-Met and Hepatocyte · See more »
Hepatocyte growth factor
Hepatocyte growth factor (HGF) (or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells, but also acts on haemopoietic progenitor cells and T cells. It has been shown to have a major role in embryonic organ development, specifically in myogenesis, in adult organ regeneration, and in wound healing.
New!!: C-Met and Hepatocyte growth factor · See more »
Hypoxia (medical)
Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level.
New!!: C-Met and Hypoxia (medical) · See more »
Hypoxia-inducible factors
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia.
New!!: C-Met and Hypoxia-inducible factors · See more »
Immunotherapy
Immunotherapy is the "treatment of disease by inducing, enhancing, or suppressing an immune response".
New!!: C-Met and Immunotherapy · See more »
Interferon
Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several pathogens, such as viruses, bacteria, parasites, and also tumor cells.
New!!: C-Met and Interferon · See more »
Interleukin
Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that were first seen to be expressed by white blood cells (leukocytes).
New!!: C-Met and Interleukin · See more »
Interleukin 2
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system.
New!!: C-Met and Interleukin 2 · See more »
K252a
K252a is an alkaloid isolated from Nocardiopisis bacteria.
New!!: C-Met and K252a · See more »
Kinase insert domain receptor
Kinase insert domain receptor (KDR, a type III receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor.
New!!: C-Met and Kinase insert domain receptor · See more »
Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
New!!: C-Met and Liver · See more »
Macrophage
Macrophages (big eaters, from Greek μακρός (makrós).
New!!: C-Met and Macrophage · See more »
Melanocyte
Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart.
New!!: C-Met and Melanocyte · See more »
Mesenchymal stem cell
Mesenchymal stem cells are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells which give rise to marrow adipose tissue).
New!!: C-Met and Mesenchymal stem cell · See more »
Mesenchyme
Mesenchyme, in vertebrate embryology, is a type of connective tissue found mostly during the development of the embryo.
New!!: C-Met and Mesenchyme · See more »
Metalloproteinase
A metalloproteinase, or metalloprotease, is any protease enzyme whose catalytic mechanism involves a metal.
New!!: C-Met and Metalloproteinase · See more »
Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
New!!: C-Met and Metastasis · See more »
Mir-199 microRNA precursor
The miR-199 microRNA precursor is a short non-coding RNA gene involved in gene regulation.
New!!: C-Met and Mir-199 microRNA precursor · See more »
Mitogen
A mitogen is a chemical substance that encourages a cell to commence cell division, triggering mitosis.
New!!: C-Met and Mitogen · See more »
Mitogen-activated protein kinase
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of protein kinase that is specific to the amino acids serine and threonine (i.e., a serine/threonine-specific protein kinase).
New!!: C-Met and Mitogen-activated protein kinase · See more »
Monoclonal antibody
Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.
New!!: C-Met and Monoclonal antibody · See more »
Morphogenesis
Morphogenesis (from the Greek morphê shape and genesis creation, literally, "beginning of the shape") is the biological process that causes an organism to develop its shape.
New!!: C-Met and Morphogenesis · See more »
Myocyte
A myocyte (also known as a muscle cell) is the type of cell found in muscle tissue.
New!!: C-Met and Myocyte · See more »
Natural killer cell
Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.
New!!: C-Met and Natural killer cell · See more »
Nerve
A nerve is an enclosed, cable-like bundle of axons (nerve fibers, the long and slender projections of neurons) in the peripheral nervous system.
New!!: C-Met and Nerve · See more »
Neuron
A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.
New!!: C-Met and Neuron · See more »
Neutrophil
Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.
New!!: C-Met and Neutrophil · See more »
Notch signaling pathway
The Notch signaling pathway is a highly conserved cell signaling system present in most multicellular organisms.
New!!: C-Met and Notch signaling pathway · See more »
PAK1
Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene.
New!!: C-Met and PAK1 · See more »
Pfizer
Pfizer Inc. is an American pharmaceutical conglomerate headquartered in New York City, with its research headquarters in Groton, Connecticut.
New!!: C-Met and Pfizer · See more »
Phagocyte
Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells.
New!!: C-Met and Phagocyte · See more »
Phagocytosis
In cell biology, phagocytosis is the process by which a cell—often a phagocyte or a protist—engulfs a solid particle to form an internal compartment known as a phagosome.
New!!: C-Met and Phagocytosis · See more »
Phenotype
A phenotype is the composite of an organism's observable characteristics or traits, such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest).
New!!: C-Met and Phenotype · See more »
Phosphatase
A phosphatase is an enzyme that uses water to cleave a phosphoric acid monoester into a phosphate ion and an alcohol.
New!!: C-Met and Phosphatase · See more »
Phosphoinositide 3-kinase
Phosphatidylinositol-4,5-bisphosphate 3-kinase (also called phosphatidylinositide 3-kinases, phosphatidylinositol-3-kinases, PI 3-kinases, PI(3)Ks, PI-3Ks or by the HUGO official stem symbol for the gene family, PI3K(s)) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.
New!!: C-Met and Phosphoinositide 3-kinase · See more »
Platelet-derived growth factor receptor
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family.
New!!: C-Met and Platelet-derived growth factor receptor · See more »
Progenitor cell
A progenitor cell is a biological cell that, like a stem cell, has a tendency to differentiate into a specific type of cell, but is already more specific than a stem cell and is pushed to differentiate into its "target" cell.
New!!: C-Met and Progenitor cell · See more »
Protease
A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.
New!!: C-Met and Protease · See more »
Proteasome
Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.
New!!: C-Met and Proteasome · See more »
Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
New!!: C-Met and Protein · See more »
Protein kinase B
Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription and cell migration.
New!!: C-Met and Protein kinase B · See more »
Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
New!!: C-Met and Protein–protein interaction · See more »
Proto-oncogene tyrosine-protein kinase Src
Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src or simply c-Src, is a non-receptor tyrosine kinase protein that in humans is encoded by the SRC gene.
New!!: C-Met and Proto-oncogene tyrosine-protein kinase Src · See more »
PTEN (gene)
Phosphatase and tensin homolog (PTEN) is a protein that, in humans, is encoded by the PTEN gene.
New!!: C-Met and PTEN (gene) · See more »
PTPRM
Receptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene.
New!!: C-Met and PTPRM · See more »
RAC1
Rac1, also known as Ras-related C3 botulinum toxin substrate 1, is a protein found in human cells.
New!!: C-Met and RAC1 · See more »
RANBP9
Ran-binding protein 9 is a protein that in humans is encoded by the RANBP9 gene.
New!!: C-Met and RANBP9 · See more »
Ras subfamily
Ras is a family of related proteins which is expressed in all animal cell lineages and organs.
New!!: C-Met and Ras subfamily · See more »
Receptor tyrosine kinase
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones.
New!!: C-Met and Receptor tyrosine kinase · See more »
Renal cell carcinoma
Renal cell carcinoma (RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine.
New!!: C-Met and Renal cell carcinoma · See more »
Scattering
Scattering is a general physical process where some forms of radiation, such as light, sound, or moving particles, are forced to deviate from a straight trajectory by one or more paths due to localized non-uniformities in the medium through which they pass.
New!!: C-Met and Scattering · See more »
Schizophrenia
Schizophrenia is a mental disorder characterized by abnormal social behavior and failure to understand reality.
New!!: C-Met and Schizophrenia · See more »
Semaphorin
Semaphorins are a class of secreted and membrane proteins that were originally identified as axonal growth cone guidance molecules.
New!!: C-Met and Semaphorin · See more »
SH2 domain
The SH2 (Src Homology 2) domain is a structurally conserved protein domain contained within the Src oncoprotein and in many other intracellular signal-transducing proteins.
New!!: C-Met and SH2 domain · See more »
SHC1
SHC-transforming protein 1 is a protein that in humans is encoded by the SHC1 gene.
New!!: C-Met and SHC1 · See more »
Signal transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.
New!!: C-Met and Signal transduction · See more »
STAT protein
Members of the signal transducer and activator of transcription (STAT) protein family are intracellular transcription factors that mediate many aspects of cellular immunity, proliferation, apoptosis and differentiation.
New!!: C-Met and STAT protein · See more »
STAT3
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene.
New!!: C-Met and STAT3 · See more »
Staurosporine
Staurosporine (antibiotic AM-2282 or STS) is a natural product originally isolated in 1977 from the bacterium Streptomyces staurosporeus.
New!!: C-Met and Staurosporine · See more »
Stem cell
Stem cells are biological cells that can differentiate into other types of cells and can divide to produce more of the same type of stem cells.
New!!: C-Met and Stem cell · See more »
Stomach cancer
Stomach cancer, also known as gastric cancer, is cancer developing from the lining of the stomach.
New!!: C-Met and Stomach cancer · See more »
SUGEN
SUGEN (Sugen) was a drug discovery company focused on development of protein kinase inhibitors.
New!!: C-Met and SUGEN · See more »
Swiss Institute of Bioinformatics
The SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation which federates bioinformatics activities throughout Switzerland.
New!!: C-Met and Swiss Institute of Bioinformatics · See more »
Tivantinib
Tivantinib (ARQ197; by Arqule, Inc.) is an experimental small molecule anti-cancer drug.
New!!: C-Met and Tivantinib · See more »
Tpr-met fusion protein
Tpr-Met fusion protein is an oncogene fusion protein consisting of TPR and MET.
New!!: C-Met and Tpr-met fusion protein · See more »
Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
New!!: C-Met and Transcription factor · See more »
Tumor antigen
Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host.
New!!: C-Met and Tumor antigen · See more »
Tumor suppressor
A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer.
New!!: C-Met and Tumor suppressor · See more »
Tyrosine kinase
A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to a protein in a cell.
New!!: C-Met and Tyrosine kinase · See more »
Ubiquitin
Ubiquitin is a small (8.5 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e. it occurs ''ubiquitously''.
New!!: C-Met and Ubiquitin · See more »
Ubiquitin ligase
A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin, recognizes a protein substrate, and assists or directly catalyzes the transfer of ubiquitin from the E2 to the protein substrate.
New!!: C-Met and Ubiquitin ligase · See more »
Von Hippel–Lindau tumor suppressor
The von Hippel–Lindau tumor suppressor also known as pVHL is a protein that in humans is encoded by the VHL gene.
New!!: C-Met and Von Hippel–Lindau tumor suppressor · See more »
White blood cell
White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
New!!: C-Met and White blood cell · See more »
Wild type
Wild type (WT) refers to the phenotype of the typical form of a species as it occurs in nature.
New!!: C-Met and Wild type · See more »
Wnt signaling pathway
The Wnt signaling pathways are a group of signal transduction pathways made of proteins that pass signals into a cell through cell surface receptors.
New!!: C-Met and Wnt signaling pathway · See more »
Wound healing
Wound healing is an intricate process in which the skin repairs itself after injury.
New!!: C-Met and Wound healing · See more »
Redirects here:
C-MET, HGFR, Hepatocyte growth factor receptor, Hgfr, MET (gene), MET kinase, Met proto-oncogene, Proto-oncogene proteins c-met, RCCP2, Rccp2.
References
[1] https://en.wikipedia.org/wiki/C-Met
