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Bovine pancreatic ribonuclease

Index Bovine pancreatic ribonuclease

Bovine pancreatic ribonuclease, also often referred to as bovine pancreatic ribonuclease A or simply RNase A, is a pancreatic ribonuclease enzyme that cleaves single-stranded RNA. [1]

48 relations: Absorbance, Allosteric regulation, Alpha helix, Anfinsen's dogma, Antigen, Armour and Company, Base pair, Beta hairpin, Beta sheet, Biomolecular structure, C-peptide, Chemical synthesis, Christian B. Anfinsen, Circular dichroism, Crystallography, Dissociation constant, Electron paramagnetic resonance, Enzyme, Enzyme catalysis, Histidine, Ion, Isomer, Loop entropy, Morpheein, Nobel Prize in Chemistry, Nuclear magnetic resonance, Oxidative folding, Pancreatic ribonuclease, Peptide bond, Proline, Protease, Protein, Protein family, Protein folding, Protein purification, Proteolysis, Pyrimidine, Raman spectroscopy, Reaction mechanism, Relative permittivity, Ribonuclease, Ribonuclease inhibitor, RNA, Robert Bruce Merrifield, Stanford Moore, Subtilisin, Thermodynamic free energy, William Howard Stein.

Absorbance

In chemistry, absorbance or decadic absorbance is the common logarithm of the ratio of incident to transmitted radiant power through a material, and spectral absorbance or spectral decadic absorbance is the common logarithm of the ratio of incident to transmitted spectral radiant power through a material.

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Allosteric regulation

In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule at a site other than the enzyme's active site.

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Alpha helix

The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.

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Anfinsen's dogma

Anfinsen's dogma (also known as the thermodynamic hypothesis) is a postulate in molecular biology that states that, at least for a small globular protein in its standard physiological environment, the native structure is determined only by the protein's amino acid sequence.

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Antigen

In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.

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Armour and Company

Armour & Company was an American company that used to be one of the five leading firms in the meat packing industry.

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Base pair

A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.

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Beta hairpin

The beta hairpin (sometimes also called beta-ribbon or beta-beta unit) is a simple protein structural motif involving two beta strands that look like a hairpin.

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Beta sheet

The β-sheet (also β-pleated sheet) is a common motif of regular secondary structure in proteins.

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Biomolecular structure

Biomolecular structure is the intricate folded, three-dimensional shape that is formed by a molecule of protein, DNA, or RNA, and that is important to its function.

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C-peptide

The connecting peptide, or C-peptide, is a short 31-amino-acid polypeptide that connects insulin's A-chain to its B-chain in the proinsulin molecule.

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Chemical synthesis

Chemical synthesis is a purposeful execution of chemical reactions to obtain a product, or several products.

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Christian B. Anfinsen

Christian Boehmer Anfinsen Jr. (March 26, 1916 – May 14, 1995) was an American biochemist.

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Circular dichroism

Circular dichroism (CD) is dichroism involving circularly polarized light, i.e., the differential absorption of left- and right-handed light.

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Crystallography

Crystallography is the experimental science of determining the arrangement of atoms in crystalline solids (see crystal structure).

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Dissociation constant

In chemistry, biochemistry, and pharmacology, a dissociation constant (K_d) is a specific type of equilibrium constant that measures the propensity of a larger object to separate (dissociate) reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into its component ions.

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Electron paramagnetic resonance

Electron paramagnetic resonance (EPR) or electron spin resonance (ESR) spectroscopy is a method for studying materials with unpaired electrons.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Enzyme catalysis

Enzyme catalysis is the increase in the rate of a chemical reaction by the active site of a protein.

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Histidine

Histidine (symbol His or H) is an α-amino acid that is used in the biosynthesis of proteins.

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Ion

An ion is an atom or molecule that has a non-zero net electrical charge (its total number of electrons is not equal to its total number of protons).

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Isomer

An isomer (from Greek ἰσομερής, isomerès; isos.

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Loop entropy

Loop entropy is the entropy lost upon bringing together two residues of a polymer within a prescribed distance.

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Morpheein

Morpheeins are proteins that can form two or more different homo-oligomers (morpheein forms), but must come apart and change shape to convert between forms.

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Nobel Prize in Chemistry

The Nobel Prize in Chemistry (Nobelpriset i kemi) is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry.

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Nuclear magnetic resonance

Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a magnetic field absorb and re-emit electromagnetic radiation.

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Oxidative folding

Oxidative protein folding is a process that is responsible for the formation of disulfide bonds between cysteine residues in proteins.

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Pancreatic ribonuclease

Pancreatic ribonucleases (RNase, RNase I, RNase A, pancreatic RNase, ribonuclease I, endoribonuclease I, ribonucleic phosphatase, alkaline ribonuclease, ribonuclease, gene S glycoproteins, Ceratitis capitata alkaline ribonuclease, SLSG glycoproteins, gene S locus-specific glycoproteins, S-genotype-assocd. glycoproteins, ribonucleate 3'-pyrimidino-oligonucleotidohydrolase) are pyrimidine-specific endonucleases found in high quantity in the pancreas of certain mammals and of some reptiles.

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Peptide bond

A peptide bond is a covalent chemical bond linking two consecutive amino acid monomers along a peptide or protein chain.

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Proline

Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins.

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Protease

A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein family

A protein family is a group of evolutionarily-related proteins.

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Protein folding

Protein folding is the physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner.

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Protein purification

Protein purification is a series of processes intended to isolate one or a few proteins from a complex mixture, usually cells, tissues or whole organisms.

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Proteolysis

Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.

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Pyrimidine

Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine.

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Raman spectroscopy

Raman spectroscopy (named after Indian physicist Sir C. V. Raman) is a spectroscopic technique used to observe vibrational, rotational, and other low-frequency modes in a system.

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Reaction mechanism

In chemistry, a reaction mechanism is the step by step sequence of elementary reactions by which overall chemical change occurs.

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Relative permittivity

The relative permittivity of a material is its (absolute) permittivity expressed as a ratio relative to the permittivity of vacuum.

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Ribonuclease

Ribonuclease (commonly abbreviated RNase) is a type of nuclease that catalyzes the degradation of RNA into smaller components.

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Ribonuclease inhibitor

Ribonuclease inhibitor (RI) is a large (~450 residues, ~49 kDa), acidic (pI ~4.7), leucine-rich repeat protein that forms extremely tight complexes with certain ribonucleases.

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RNA

Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.

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Robert Bruce Merrifield

Robert Bruce Merrifield (July 15, 1921 – May 14, 2006) was an American biochemist who won the Nobel Prize in Chemistry in 1984 for the invention of solid phase peptide synthesis.

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Stanford Moore

Stanford Moore (September 4, 1913 – August 23, 1982) was an American biochemist.

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Subtilisin

Subtilisin is a non-specific protease (a protein-digesting enzyme) initially obtained from Bacillus subtilis.

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Thermodynamic free energy

The thermodynamic free energy is the amount of work that a thermodynamic system can perform.

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William Howard Stein

William Howard Stein (June 25, 1911 – February 2, 1980) was an American biochemist.

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Redirects here:

Bovine ribonuclease pancreatic, RNase S, Ribonuclease S, Rnase S.

References

[1] https://en.wikipedia.org/wiki/Bovine_pancreatic_ribonuclease

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