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Robalzotan

Index Robalzotan

Robalzotan (NAD-299, AZD-7371) is a selective antagonist at the 5-HT1A receptor. [1]

14 relations: Animal testing on rodents, Antidepressant, AstraZeneca, Autoreceptor, Binding selectivity, Citalopram, Ebalzotan, Irritable bowel syndrome, Receptor (biochemistry), Receptor antagonist, Selective serotonin reuptake inhibitor, Serotonin, UH-301, 5-HT1A receptor.

Animal testing on rodents

Rodents are commonly used in animal testing, particularly mice and rats, but also guinea pigs, hamsters, gerbils and others.

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Antidepressant

Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.

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AstraZeneca

AstraZeneca plc is an Anglo–Swedish multinational pharmaceutical and biopharmaceutical company.

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Autoreceptor

An autoreceptor is a type of receptor located in the membranes of presynaptic nerve cells.

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Binding selectivity

Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

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Citalopram

Citalopram (brand names: Celexa, Cipramil and others) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class.

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Ebalzotan

Ebalzotan (NAE-086) is a selective 5-HT1A receptor agonist.

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Irritable bowel syndrome

Irritable bowel syndrome (IBS) is a group of symptoms—including abdominal pain and changes in the pattern of bowel movements without any evidence of underlying damage.

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Selective serotonin reuptake inhibitor

Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.

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Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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UH-301

UH-301 is a drug and research chemical widely used in scientific studies.

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5-HT1A receptor

The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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Redirects here:

C18H23FN2O2, Robalzotane.

References

[1] https://en.wikipedia.org/wiki/Robalzotan

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